Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anton Aboukhalil"'
Autor:
Dolrudee Jumlongras, Salil A Lachke, Daniel J O'Connell, Anton Aboukhalil, Xiao Li, Sung E Choe, Joshua W K Ho, Annick Turbe-Doan, Erin A Robertson, Bjorn R Olsen, Martha L Bulyk, Brad A Amendt, Richard L Maas
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38568 (2012)
To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified a regulatory region loca
Externí odkaz:
https://doaj.org/article/08e5f2f2b31c43439d3dcdafd28aa674
Background: Over the past two decades, high false alarm (FA) rates have remained an important yet unresolved concern in the Intensive Care Unit (ICU). High FA rates lead to desensitization of the attending staff to such warnings, with associated slow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c529b8c7b64c4a2aaaf5728e2845e55
https://ora.ox.ac.uk/objects/uuid:e109d5be-62dd-439e-b976-5563c764d110
https://ora.ox.ac.uk/objects/uuid:e109d5be-62dd-439e-b976-5563c764d110
Autor:
Adrian D. Haimovich, Brian W. Busser, Xianmin Zhu, Alan M. Michelson, Yongsok Kim, Neal Jeffries, Martha L. Bulyk, Anton Aboukhalil, Shaad M. Ahmad, Terese Tansey
Publikováno v:
Development (Cambridge, England)
A common theme in developmental biology is the repeated use of the same gene in diverse spatial and temporal domains, a process that generally involves transcriptional regulation mediated by multiple separate enhancers, each with its own arrangement
Autor:
Martha L. Bulyk, Anton Aboukhalil
Publikováno v:
Bioinformatics. 28:1446-1454
Motivation: Sequence analysis algorithms are often applied to sets of DNA, RNA or protein sequences to identify common or distinguishing features. Controlling for sequence length variation is critical to properly score sequence features and identify
Autor:
Irfan Saadi, Arlene V. Drack, Resy Cavallesco, Salil A. Lachke, Richard L. Maas, Anne C.H. Tsai, Yingzi Yue, Emily Hodges, Stephen C. Kneeland, Martha L. Bulyk, Takbum Ohn, Hanan E. Shamseldin, Paul A. Anderson, Richard S. Smith, Gregory J. Hannon, K. Saidas Nair, Simon W. M. John, Suad AlFadhli, Anton Aboukhalil, Amal Al-Hajeri, Abdul Mutalib Behbehani, Fowzan S. Alkuraya, Mihai Cosma, Gareth R. Howell
Publikováno v:
Science. 331:1571-1576
The precise transcriptional regulation of gene expression is essential for vertebrate development, but the role of posttranscriptional regulatory mechanisms is less clear. Cytoplasmic RNA granules (RGs) function in the posttranscriptional control of
Publikováno v:
Annals of the New York Academy of Sciences. 1039:166-175
Dual-state adaptation of motor responses has been known for some time. A more recent development is a form of dual-state adaptation known as "context-specific adaptation," which was explored through the use of saccade gain adaptation. In this model,
Autor:
Polakit Teekakirikul, Ju Chen, David M. McKean, Danos C. Christodoulou, Andrea A. Domenighetti, Jonathan G. Seidman, Kenji Onoue, Daniel S. Herman, Barbara McDonough, Jochen D. Muehlschlegel, Martha L. Bulyk, Hiroko Wakimoto, Joshua M. Gorham, Christine E. Seidman, Steve Depalma, Gyan Srivastava, Philip L. De Jager, David A. Conner, Stephen Chang, Seda Eminaga, Anton Aboukhalil
Publikováno v:
The Journal of clinical investigation, vol 124, iss 3
The transcriptome is subject to multiple changes during pathogenesis, including the use of alternate 5' start-sites that can affect transcription levels and output. Current RNA sequencing techniques can assess mRNA levels, but do not robustly detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab0dba363821f981e64c6db12e739a4
https://escholarship.org/uc/item/48j0z1gx
https://escholarship.org/uc/item/48j0z1gx
Autor:
Ivan Ovcharenko, Xianmin Zhu, Sébastien Michaud, Elizabeth J. Cozart, Neal Jeffries, Di Huang, Alan M. Michelson, Anton Aboukhalil, Shaad M. Ahmad, Martha L. Bulyk, Brian W. Busser
Publikováno v:
Development (Cambridge, England)
The Drosophila heart is composed of two distinct cell types, the contractile cardial cells (CCs) and the surrounding non-muscle pericardial cells (PCs), development of which is regulated by a network of conserved signaling molecules and transcription
Autor:
Martha L. Bulyk, Anastasia Vedenko, Yongsok Kim, Alan M. Michelson, Brian W. Busser, Martin Porsch, Antonina Iagovitina, Preston W. Estep, Xianmin Zhu, Aditi Singhania, Alexandre Palagi, Stephen S. Gisselbrecht, Caitlin E. Gamble, Anton Aboukhalil, Luis A. Barrera
Publikováno v:
Nature methods. 10(8)
Transcriptional enhancers are a primary mechanism by which tissue-specific gene expression is achieved. Despite the importance of these regulatory elements in development, responses to environmental stresses and disease, testing enhancer activity in
Autor:
Joshua W. K. Ho, Sung E. Choe, Dolrudee Jumlongras, Bjorn R. Olsen, Annick Turbe-Doan, Brad A. Amendt, Xiao Li, Richard L. Maas, Erin A. Robertson, Salil A. Lachke, Martha L. Bulyk, Anton Aboukhalil, Daniel J. O’Connell
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38568 (2012)
PLoS
PLoS ONE
PLoS
PLoS ONE
To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified a regulatory region loca