Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anton, Dobrin"'
Autor:
Zeguo Zhao, Mohamad Hamieh, Justin Eyquem, Michel Sadelain, Maria Sjöstrand, Jorge Mansilla-Soto, Sascha Haubner, Judith Feucht, Noémie Paillon, Andres Zucchetti, Zhuoning Li, Pieter Lindenbergh, Michelle Saetersmoen, Mathieu Maurin, Archana Iyer, Anton Dobrin, Andreina Garcia Angus, Matthew Miele, Theodoros Giavridis, Sjoukje van der Stegen, Fella Tamzalit, Morgan Huse, Ronald Hendrickson, Claire Hivroz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/595628448f684db780a076008ffd5232
Autor:
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie Yang, Yingqian Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
Publikováno v:
Nature. 615:315-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c56c418077125d7b588832998727be
https://doi.org/10.1038/s41586-022-05692-z
https://doi.org/10.1038/s41586-022-05692-z
Autor:
Marta Łuksza, Zachary M. Sethna, Luis A. Rojas, Jayon Lihm, Barbara Bravi, Yuval Elhanati, Kevin Soares, Masataka Amisaki, Anton Dobrin, David Hoyos, Pablo Guasp, Abderezak Zebboudj, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Zagaa Odgerel, Joanne Leung, Rajya Kappagantula, Alvin Makohon-Moore, Amber Johns, Anthony Gill, Mathieu Gigoux, Jedd Wolchok, Taha Merghoub, Michel Sadelain, Erin Patterson, Remi Monasson, Thierry Mora, Aleksandra M. Walczak, Simona Cocco, Christine Iacobuzio-Donahue, Benjamin D. Greenbaum, Vinod P. Balachandran
Publikováno v:
Nature. 606:389-395
Cancer immunoediting1is a hallmark of cancer2that predicts that lymphocytes kill more immunogenic cancer cells to cause less immunogenic clones to dominate a population. Although proven in mice1,3, whether immunoediting occurs naturally in human canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b02033b56c443b58e086f5f9943068
https://doi.org/10.1038/s41586-022-04735-9
https://doi.org/10.1038/s41586-022-04735-9
Autor:
Andrew Chow, Fathema Z. Uddin, Levi Mangarin, Hira Rizvi, Anton Dobrin, Sam Tischfield, Alvaro Quintanal-Villalonga, Joseph M. Chan, Nisargbhai Shah, Viola Allaj, Parvathy Manoj, Marissa Mattar, Maximiliano Meneses, Michael Liu, Rebecca Landau, Mariana Ward, Amanda Kulick, Charlene Kwong, Matthew Wierzbicki, Jessica Yavner, Shweta S. Chavan, Abigail Farillas, Aliya Holland, Harsha Sridhar, Metamia Ciampricotti, Daniel Hirschhorn, Allison L Richards, Mark T.A. Donoghue, Glenn Heller, Christopher A. Klebanoff, Matthew D. Hellmann, Elisa de Stanchina, Triparna Sen, Jedd D. Wolchok, Taha Merghoub, Charles M. Rudin
The repertoire of tumor-infiltrating lymphocytes (TILs) can be vast, and many of these TILs are not endowed with tumor reactivity. While a number of reports have shown that tumor-reactive TILs express CD39, few reports have demonstrated that converse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6058641e531bed0ad29de3844283ca1
https://doi.org/10.1101/2022.01.24.477554
https://doi.org/10.1101/2022.01.24.477554
Autor:
Andrew, Chow, Fathema Z, Uddin, Michael, Liu, Anton, Dobrin, Barzin Y, Nabet, Levi, Mangarin, Yonit, Lavin, Hira, Rizvi, Sam E, Tischfield, Alvaro, Quintanal-Villalonga, Joseph M, Chan, Nisargbhai, Shah, Viola, Allaj, Parvathy, Manoj, Marissa, Mattar, Maximiliano, Meneses, Rebecca, Landau, Mariana, Ward, Amanda, Kulick, Charlene, Kwong, Matthew, Wierzbicki, Jessica, Yavner, Jacklynn, Egger, Shweta S, Chavan, Abigail, Farillas, Aliya, Holland, Harsha, Sridhar, Metamia, Ciampricotti, Daniel, Hirschhorn, Xiangnan, Guan, Allison L, Richards, Glenn, Heller, Jorge, Mansilla-Soto, Michel, Sadelain, Christopher A, Klebanoff, Matthew D, Hellmann, Triparna, Sen, Elisa, de Stanchina, Jedd D, Wolchok, Taha, Merghoub, Charles M, Rudin
Publikováno v:
Immunity.
Improved identification of anti-tumor T cells is needed to advance cancer immunotherapies. CD39 expression is a promising surrogate of tumor-reactive CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25c507bc18d4b94dbcacd714ff229233
https://pubmed.ncbi.nlm.nih.gov/36574773
https://pubmed.ncbi.nlm.nih.gov/36574773
Autor:
Andrew Chow, Fathema Z. Uddin, Michael Liu, Anton Dobrin, Barzin Y. Nabet, Levi Mangarin, Yonit Lavin, Hira Rizvi, Sam E. Tischfield, Alvaro Quintanal-Villalonga, Joseph M. Chan, Nisargbhai Shah, Viola Allaj, Parvathy Manoj, Marissa Mattar, Maximiliano Meneses, Rebecca Landau, Mariana Ward, Amanda Kulick, Charlene Kwong, Matthew Wierzbicki, Jessica Yavner, Jacklynn Egger, Shweta S. Chavan, Abigail Farillas, Aliya Holland, Harsha Sridhar, Metamia Ciampricotti, Daniel Hirschhorn, Xiangnan Guan, Allison L. Richards, Glenn Heller, Jorge Mansilla-Soto, Michel Sadelain, Christopher A. Klebanoff, Matthew D. Hellmann, Triparna Sen, Elisa de Stanchina, Jedd D. Wolchok, Taha Merghoub, Charles M. Rudin
Publikováno v:
Immunity. 56:93-106.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14fbac1e6d8e741eb84a96a84b96c94b
https://doi.org/10.1016/j.immuni.2022.12.001
https://doi.org/10.1016/j.immuni.2022.12.001
Autor:
Sascha Haubner, Zeguo Zhao, Ronald C. Hendrickson, Andreina Garcia Angus, Claire Hivroz, Noémie Paillon, Judith Feucht, Mathieu Maurin, Michelle Saetersmoen, Archana Iyer, Michel Sadelain, Andrés Ernesto Zucchetti, Jorge Mansilla-Soto, Mohamad Hamieh, Sjoukje J. C. van der Stegen, Justin Eyquem, Anton Dobrin, Maria L. Sjostrand, Fella Tamzalit, Morgan Huse, Zhuoning Li, Pieter Lindenbergh, Matthew M. Miele, Theodoros Giavridis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundChimeric antigen receptors (CARs) engage antigen independently of HLA and enable sustained T cell proliferation when they are endowed with both activating and costimulatory functions. While remission rates have been noticeably elevated in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6173f2a5378d8995bd987f3ac498d98
https://doaj.org/article/595628448f684db780a076008ffd5232
https://doaj.org/article/595628448f684db780a076008ffd5232
Autor:
Nayan Jain, Zeguo Zhao, Richard Koche, Yosi Gozlan, David Brocks, Tali Raveh-Sadka, Danny Wells, Anton Dobrin, Yuzhe Shi, Michael Lopez, Gertrude Gunset, Michel Sadelain
Publikováno v:
Cancer Research. 82:5583-5583
Retrovirally encoded CD19-specific CARs that incorporate CD28 and CD3z signaling motifs (Rv-1928z) have induced remarkable responses in patients with refractory leukemia and lymphoma. These CARs induce a strong effector differentiation program in T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9af417b7e26d5e6d79baa3ebba1ebe2f
https://doi.org/10.1158/1538-7445.am2022-5583
https://doi.org/10.1158/1538-7445.am2022-5583
Autor:
Michel Sadelain, Jie Sun, Judith Feucht, Annalisa Cabriolu, Josef Leibold, Anton Dobrin, Zeguo Zhao, Yu-Jui Ho, Justin Eyquem, Mohamad Hamieh
Publikováno v:
Nature Medicine. 25:82-88
Chimeric antigen receptors (CARs) are synthetic receptors that target and reprogram T cells to acquire augmented antitumor properties1. CD19-specific CARs that comprise CD28 and CD3ζ signaling motifs2 have induced remarkable responses in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4eab2752596ff1198db83ce3f2beeb
https://doi.org/10.1038/s41591-018-0290-5
https://doi.org/10.1038/s41591-018-0290-5
Autor:
Nayan Jain, Zeguo Zhao, Richard Koche, Yosi Gozlan, David Brocks, Tali Raveh-Sadka, Danny Wells, Anton Dobrin, Yuzhe Shi, Michael Lopez, Gertrude Gunset, Michel Sadelain
Publikováno v:
The Journal of Immunology. 208:122.05-122.05
Retrovirally encoded CD19-specific CARs that incorporate CD28 and CD3z signaling motifs (Rv-1928z) have induced remarkable responses in patients with refractory leukemia and lymphoma. These CARs, however, induce a strong effector differentiation prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f46a91bb8c6e318cd8f3b913670e243
https://doi.org/10.4049/jimmunol.208.supp.122.05
https://doi.org/10.4049/jimmunol.208.supp.122.05