Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Anton, Buzdin"'
Autor:
Alexander Modestov, Marianna Zolotovskaia, Maria Suntsova, Galina Zakharova, Aleksander Seryakov, Ivana Jovcevska, Jernej Mlakar, Elena Poddubskaya, Aleksey Moisseev, Grigory Vykhodtsev, Sergey Roumiantsev, Maksim Sorokin, Victor Tkachev, Aleksander Simonov, Anton Buzdin
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Glioblastoma (GBM) is the most aggressive and lethal central nervous system (CNS) tumor. The treatment strategy is mainly surgery and/or radiation therapy, both combined with adjuvant temozolomide (TMZ) chemotherapy. Historically, methyla
Externí odkaz:
https://doaj.org/article/0cbfd8ce25624529b0c97414dc866f4a
Autor:
Rijalda Mekic, Marianna A. Zolotovskaia, Maksim Sorokin, Tharaa Mohammad, Nina Shaban, Ivan Musatov, Victor Tkachev, Alexander Modestov, Alexander Simonov, Denis Kuzmin, Anton Buzdin
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe differential ratio of nonsynonymous to synonymous nucleotide substitutions (dN/dS) is a common measure of the rate of structural evolution in proteincoding genes. In addition, we recently suggested that the proportion of transposable
Externí odkaz:
https://doaj.org/article/70860e63085c4a2fbe2eea7456df5f6b
Autor:
Dmitry Kamashev, Nina Shaban, Galina Zakharova, Alexander Modestov, Мargarita Kamynina, Sergey Baranov, Anton Buzdin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Dual inhibitors of HER2 and EGFR, such as lapatinib, have shown significant efficacy for the therapy of HER2-positive breast cancer. Previous experiments showed that in cell cultures, the efficacy of lapatinib was significantly reduced by exposure to
Externí odkaz:
https://doaj.org/article/3e14a79eb1d44eacb3f92765d89704fa
Autor:
Irina Alekseenko, Lyudmila Zhukova, Liya Kondratyeva, Anton Buzdin, Igor Chernov, Eugene Sverdlov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10454 (2024)
Fifty-two years have passed since President Nixon launched the “War on Cancer”. Despite unparalleled efforts and funds allocated worldwide, the outlined goals were not achieved because cancer treatment approaches such as chemotherapy, radiation t
Externí odkaz:
https://doaj.org/article/2d605e7a99f046dd9fcf74a81e54e0b0
Autor:
Aleksey Drobyshev, Alexander Modestov, Maria Suntsova, Elena Poddubskaya, Alexander Seryakov, Aleksey Moisseev, Maksim Sorokin, Victor Tkachev, Galina Zakharova, Aleksander Simonov, Marianna A. Zolotovskaia, Anton Buzdin
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The TERT gene encodes the reverse transcriptase subunit of telomerase and is normally transcriptionally suppressed in differentiated human cells but reactivated in cancers where its expression is frequently associated with poor survival prognosis. He
Externí odkaz:
https://doaj.org/article/3dc19069f31e4c6d85a36102e9c4f88d
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/52edd5c0a0fd44a888a058db32dbd1b5
Autor:
Annamaria Salvati, Carlo Ferravante, Jessica Lamberti, Teresa Rocco, Elena Alexandrova, Ylenia D’Agostino, Maksim Sorokin, Victor Efimov, Anton Buzdin, Oriana Strianese, Giovanni Nassa, Roberta Tarallo, Alessandro Weisz, Francesca Rizzo, Giorgio Giurato
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-6 (2023)
Abstract The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host transcriptomics profiling provides comprehensive understanding of how the virus interacts w
Externí odkaz:
https://doaj.org/article/91fe694c20ef40d6a40d21a5214d6443
Autor:
Nicolas Borisov, Victor Tkachev, Alexander Simonov, Maxim Sorokin, Ella Kim, Denis Kuzmin, Betul Karademir-Yilmaz, Anton Buzdin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Co-normalization of RNA profiles obtained using different experimental platforms and protocols opens avenue for comprehensive comparison of relevant features like differentially expressed genes associated with disease. Currently, most o
Externí odkaz:
https://doaj.org/article/bc9b1b45fed6475d95b7a77ee28fe063
Autor:
Maxim Sorokin, Marianna Zolotovskaia, Daniil Nikitin, Maria Suntsova, Elena Poddubskaya, Alexander Glusker, Andrew Garazha, Alexey Moisseev, Xinmin Li, Marina Sekacheva, David Naskhletashvili, Alexander Seryakov, Ye Wang, Anton Buzdin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background: Overall survival of advanced colorectal cancer (CRC) patients remains poor, and gene expression analysis could potentially complement detection of clinically relevant mutations to personalize CRC treatments. Methods: We performed
Externí odkaz:
https://doaj.org/article/f0e65dd2612144beba125d5e02bdbed1
Publikováno v:
HemaSphere, Vol 7, p e447749a (2023)
Externí odkaz:
https://doaj.org/article/9493972708844eff91318cd0ee45b16f