Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antoinette Chillemi"'
Autor:
Robert J. Soiffer, Stephen McLaughlin, Renaud Capdeville, Catherine J. Wu, Jerome Ritz, Ephraim P. Hochberg, Donna Neuberg, Daniel J. DeAngelo, Ilene Galinsky, Edwin P. Alyea, Antoinette Chillemi, Richard Stone
Publikováno v:
Leukemia & Lymphoma. 43:2281-2289
PCR for the BCR/ABL fusion transcript provides a highly sensitive and specific method for detecting minimal residual disease in patients with chronic myeloid leukemia (CML). We sought to determine if quantitative PCR measurement of peripheral blood B
Autor:
Elizabeth G. Carideo, Peter W. Marks, Olivier Munoz, Donna Neuberg, Arnold S. Freedman, Peter O'Connell, Joachim L. Schultze, John W. Donovan, Hervé Husson, Antoinette Chillemi
Publikováno v:
Blood. 99:282-289
Follicular lymphomas (FLs) are neoplastic counterparts of normal germinal center (GC) B cells. FLs are characterized by t(14;18) with deregulation of the Bcl-2 (BCL2) gene. The presence of t(14;18) and overexpression of Bcl-2 is necessary, but not su
Autor:
Stephen H. McLaughlin, Jerome Ritz, Xiaofeng Yang, Edwin P. Alyea, Catherine J. Wu, Glenn Dranoff, Kathy S. Wang, Robert J. Soiffer, Christine Canning, Antoinette Chillemi, Philip W. Kantoff
Publikováno v:
Proceedings of the National Academy of Sciences. 98:7492-7497
This report describes a tumor-associated antigen, termed CML66, initially cloned from a chronic myelogenous leukemia (CML) cDNA expression library. CML66 encodes a 583-aa protein with a molecular mass of 66 kDa and no significant homology to other kn
Autor:
Enrica Orsini, Christine Canning, Emmanuel Zorn, Robert J. Soiffer, Catherine J. Wu, Edwin P. Alyea, Jerome Ritz, Antoinette Chillemi, Brady L. Stein
Publikováno v:
Transplantation. 71:1131-1137
Background. In patients with chronic myelocytic leukemia (CML), the breakpoint cluster region and fusion between the BCR and the c-ABL genes (BCR-ABL) oncogen product is a potential tumor-specific antigen. Previous studies have shown that T cells spe
Autor:
Jerome Ritz, Donna Neuberg, Catherine J. Wu, Edwin P. Alyea, Enrica Orsini, Antoinette Chillemi, Robert J. Soiffer
Publikováno v:
Blood. 95:352-359
CDR3 spectratyping was used to analyze the complexity of the T-cell repertoire and to define the mechanisms and kinetics of the reconstitution of T-cell immunity after allogeneic bone marrow transplantation (BMT). This method, which is based on polym
Autor:
Catherine J. Wu, Antoinette Chillemi, Edwin P. Alyea, Enrica Orsini, Donna Neuberg, Robert J. Soiffer, Jerome Ritz
Publikováno v:
Blood. 95:352-359
CDR3 spectratyping was used to analyze the complexity of the T-cell repertoire and to define the mechanisms and kinetics of the reconstitution of T-cell immunity after allogeneic bone marrow transplantation (BMT). This method, which is based on polym
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:2923-2931
The Epstein-Barr virus (EBV) thymidine kinase (TK) was expressed in mammalian 143B TK − cells to investigate its substrate specificity. The herpes simplex virus type 1 (HSV-1) TK was similarly expressed for comparison. Both viral TKs conferred a TK
Publikováno v:
Plasmid. 40:164-168
In large and complex vectors a single restriction enzyme recognition site may be available for introduction of additional DNA requiring the development of linker fragments to create compatible insertion sites. This technology can be time consuming an
Autor:
Catherine J. Wu, Edie Weller, Ephraim P. Hochberg, Roberto Bellucci, Robert L. Schlossman, Robert J. Soiffer, Kenneth C. Anderson, Antoinette Chillemi, Jerome Ritz, Christine Canning, Edwin P. Alyea
Publikováno v:
Blood. 99(12)
Reconstitution of T-cell immunity after bone marrow transplantation (BMT) is often delayed, resulting in a prolonged period of immunodeficiency. Donor lymphocyte infusion (DLI) has been used to enhance graft-versus-leukemia activity after BMT, but th
Autor:
Catherine J. Wu, Kelly E. Hartman, Edwin P. Alyea, Christine Canning, Antoinette Chillemi, Spyros A. Kalams, Donna Neuberg, Jerome Ritz, Ephraim P. Hochberg, Robert J. Soiffer
Publikováno v:
Blood. 98(4)
Following myeloablative therapy, it is unknown to what extent age-dependent thymic involution limits the generation of new T cells with a diverse repertoire. Normal T-cell receptor gene rearrangement in T-cell progenitors results in the generation of