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pro vyhledávání: '"Antoine-Scott Badin"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Currently there is no widely accepted animal model reproducing the full pathological profile of Alzheimer’s disease (AD), since the basic mechanisms of neurodegeneration are still poorly understood. We have proposed that the interaction between the
Externí odkaz:
https://doaj.org/article/232d88d365c44629b1d71d6d1f0bb080
Publikováno v:
Neurophotonics. 4(3)
Optical imaging with voltage-sensitive dyes enables the visualization of extensive yet highly transient coalitions of neurons (assemblies) operating throughout the brain on a subsecond time scale. We suggest that operating at the mesoscale level of b
Publikováno v:
Frontiers in Neural Circuits
‘Neuronal assemblies’ are defined here as coalitions within the brain of millions of neurons extending in space up to 1-2 millimetres, and lasting for hundreds of milliseconds: as such they could potentially link bottom-up, micro-scale with top-d
Autor:
Antoine-Scott Badin, Susan A. Greenfield, Catherine Heffner, Clive W. Coen, Cristina Tormo-Garcia, Paul Morrill, Henry Tu, Sara Garcia-Ratés, Gwenael Pottiez
Publikováno v:
Neuropharmacology. 105
The primary cause of Alzheimer's disease is unlikely to be the much studied markers amyloid beta or tau. Their widespread distribution throughout the brain does not account for the specific identity and deep subcortical location of the primarily vuln
Publikováno v:
Neuropharmacology. 105
Previous studies have suggested that neurodegeneration is an aberrant form of development, mediated by a novel peptide from the C-terminus of acetylcholinesterase (AChE). Using voltage-sensitive dye imaging we have investigated the effects of a synth
Publikováno v:
Neuropharmacology. 73
Acetylcholinesterase (AChE) is now well known to have a secondary, non-enzymatic function independent of cholinergic transmission. In the last decade, the part of the molecule responsible for this action has been identified, i.e. a 14 amino acid pept