Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Antoine Wallabregue"'
1
Antibody-based Imaging of Bioreductive Prodrug Release in Hypoxia
Autor: Cagla Tosun, Maxim Mallerman, Antoine Wallabregue, Sarah Phillips, Claire Edwards, Stuart Conway, Ester Hammond
Regions of hypoxia occur in most tumors and predict for poor patient prognosis. Hypoxia-activated prodrugs provide an ideal strategy to target the aggressive, hypoxic fraction of a tumor while protecting the normal tissue from toxicity. A key challen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae222ec12cc804a300f5e1332ebe65d
https://doi.org/10.26434/chemrxiv-2023-9n5s0
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2
Two color imaging of different hypoxia levels in cancer cells
Autor: Antoine Wallabregue, Hannah Bolland, Stephen Faulkner, Ester Hammond, Stuart Conway
Hypoxia (low oxygen levels) exists in a wide range of biological contexts, including plants roots, bacterial biofilms, and solid tumors. In all cases, hypoxia elicits responses affecting the biological system that is experiencing low oxygen that impa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::085d7dd52719704ddf6cf1b502d34628
https://doi.org/10.26434/chemrxiv-2022-tqbw0
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3
Synthesis and properties of chiral fluorescent helicene-BODIPY conjugates
Autor: Pau Moneva Lorente, Francesco Zinna, Lorenzo Di Bari, Antoine Wallabregue, Céline Besnard, Jérôme Lacour
Publikováno v: Organic and Biomolecular Chemistry, Vol. 18, No 38 (2020) pp. 7677-7684
A series of chiral fluorescent helicene-BODIPY conjugates was prepared by the regioselective formylation of aza[4]helicene precursors and then an efficient one-pot two-step BODIPY synthesis (13 examples, 28-82%). Fused conjugates exhibit absorption a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cd029036d60deace874056d831a685
http://hdl.handle.net/11568/1067548
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4
Bright Electrochemiluminescence Tunable in the Near-infrared of Chiral Cationic Helicene Chromophores
Autor: Jérôme Lacour, Johann Bosson, Antoine Wallabregue, Catherine Adam, Neso Sojic, Geraldine M. Labrador, Laurent Bouffier, Haidong Li
Publikováno v: J. Phys. Chem. C.
Journal of Physical Chemistry. C, Vol. 121, No 1 (2017) pp. 785-792
Journal of Physical Chemistry C
Journal of Physical Chemistry C, American Chemical Society, 2017, 121 (1), pp.785-792. ⟨10.1021/acs.jpcc.6b11831⟩
Cationic helicenes are ortho-fused polyaromatics which exhibit well-defined and stable helical conformations with original absorption and emission properties in the red to near-infrared spectral ranges. Herein, a selection of cationic [4] and [6]heli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520a938c2ed829f040e3e031289e78ef
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5
Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe
Autor: Antoine Wallabregue, Eric Bakker, Peter S. Sherin, Dimitri Moreau, Jean Gruenberg, Zdenka Jarolimova, Pau Moneva Lorente, Eric Vauthey, Jérôme Lacour
Publikováno v: Journal of the American Chemical Society
J. Am. Chem. Soc.
Journal of the American Chemical Society, Vol. 138, No 6 (2016) pp. 1752-1755
Late endosomes are a major trafficking hub in the cell at the crossroads between endocytosis, autophagy, and degradation in lysosomes. Herein is disclosed the first small molecule allowing their selective imaging and monitoring in the form of a diaza
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a17605c497bebc87e1c6fe6c556f9c3
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7
Efficient annihilation electrochemiluminescence of cationic helicene luminophores
Autor: Haidong Li, Silvia Voci, Neso Sojic, Geraldine M. Labrador, Simon Pascal, Johann Bosson, Romain Duwald, Irene Hernández Delgado, Jérôme Lacour, Catherine Adam, Laurent Bouffier, Antoine Wallabregue
Publikováno v: Chemelectrochem, Vol. 4, No 7 (2017) pp. 1750-1756
ChemElectroChem
ChemElectroChem, Weinheim : Wiley-VCH, 2017, 4 (7), pp.1750-1756. ⟨10.1002/celc.201600906⟩
The electrochemistry and annihilation electrochemiluminescence (ECL) of a series of chiral cationic helicene luminophores containing various substituents were investigated in acetonitrile solvent. The electrochemical characterization evidenced a syst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e538f03251a78269c4b4261e3e1320
https://archive-ouverte.unige.ch/unige:95480
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8
Modular Synthesis of pH-Sensitive Fluorescent Diaza[4]helicenes
Autor: Antoine Wallabregue, Joyram Guin, Céline Besnard, Jérôme Lacour, Eric Vauthey, Petr Sherin
Publikováno v: European Journal of Organic Chemistry. 2014:6431-6438
Configurationally stable diaza[4]helicenes have been prepared in two steps by using a particularly facile N–N bond-cleavage reaction. The synthetic procedure uses hydrazine (NH2NH2) for the introduction of a single nitrogen atom. The strategy is ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::900b3e950260008f5c114120bb58c19e
https://doi.org/10.1002/ejoc.201402863
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10
Functionalized cationic [4]helicenes with unique tuning of absorption, fluorescence and chiroptical properties up to the far-red range
Autor: Christoph Nancoz, Jérôme Lacour, I. Hernández Delgado, Laure Guénée, Jamie L. Lunkley, Simon Pascal, Gilles Muller, Romain Duwald, Eric Vauthey, Roberto C. Tovar, Antoine Wallabregue, Céline Besnard
Publikováno v: Chemical Science
Chemical Science, The Royal Society of Chemistry, 2016, 7 (7), pp.4685-4693. ⟨10.1039/C6SC00614K⟩
Chemical Science, Vol. 7, No 7 (2016) pp. 4685-4693
Chem. Sci.
Unprecedented regioselective post-functionalization of racemic and enantiopure cationic diaza [4]helicenes is afforded. The peripheral auxochrome substituents allow a general tuning of the electrochemical, photophysical and chiroptical properties of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ed1cdf4f48a5fcd3ac84b86dfa0906
https://hal.archives-ouvertes.fr/hal-02999921
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