Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Antoine Taly"'
Autor:
Mélody Caillot, Hadjer Miloudi, Antoine Taly, Nuria Profitós‐Pelejà, Juliana C. Santos, Marcelo L. Ribeiro, Elsa Maitre, Simon Saule, Gaël Roué, Fabrice Jardin, Brigitte Sola
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2546-2564 (2023)
Exportin 1 (XPO1) is the main nuclear export receptor that controls the subcellular trafficking and the functions of major regulatory proteins. XPO1 is overexpressed in various cancers and small inhibitors of nuclear export (SINEs) have been develope
Externí odkaz:
https://doaj.org/article/15e5148ed1e04b5480ee7573912d7a4b
Autor:
Francisco Andrés Peralta, Mélaine Balcon, Adeline Martz, Deniza Biljali, Federico Cevoli, Benoit Arnould, Antoine Taly, Thierry Chataigneau, Thomas Grutter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
PIEZO proteins are large, mechanically-activated trimeric ion channels. Here the authors report a light-gated mouse PIEZO1 channel, mOP1, whereby an azobenzene-based photoswitch covalently localised at the extracellular apex of a transmembrane helix,
Externí odkaz:
https://doaj.org/article/6e2b23ec63e6488caee682f240ae2c00
Autor:
Zineb Soualah, Antoine Taly, Lucille Crespin, Ophélie Saulais, Daniel Henrion, Claire Legendre, Hélène Tricoire-Leignel, Christian Legros, César Mattei
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Fipronil (FPN) is a worldwide-used neurotoxic insecticide, targeting, and blocking GABAA receptors (GABAARs). Beyond its efficiency on insect GABAARs, FPN causes neurotoxic effects in humans and mammals. Here, we investigated the mode of action of FP
Externí odkaz:
https://doaj.org/article/ceb9ff75ecb04493bc3f8dee993d1132
Publikováno v:
Sciences du Jeu, Vol 16 (2021)
Externí odkaz:
https://doaj.org/article/1d8d04c817ab48f1b45dcc844b12fe66
Publikováno v:
Sciences du Jeu, Vol 16 (2021)
Escape games have become very popular in recent years, with a growing focus on their narrative aspects. While immersion is presented as a salient feature of this game experience, there is a lack of models to analyze the immersion of players in an esc
Externí odkaz:
https://doaj.org/article/eec466d89a0b45bca90819a957dc80c7
Publikováno v:
eLife, Vol 10 (2021)
Pentameric ligand-gated ion channels (pLGICs) mediate chemical signaling through a succession of allosteric transitions that are yet not completely understood as intermediate states remain poorly characterized by structural approaches. In a previous
Externí odkaz:
https://doaj.org/article/47b01ac4ec284c219fa466c9ed105727
Autor:
Damien Lemoine, Sarah Mondoloni, Jérome Tange, Bertrand Lambolez, Philippe Faure, Antoine Taly, Ludovic Tricoire, Alexandre Mourot
Publikováno v:
eLife, Vol 9 (2020)
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacol
Externí odkaz:
https://doaj.org/article/0ca7be8901764454b40d9cd49bbd0bb9
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Many recent publications highlight the large role of the pivotal eukaryotic nuclear export protein exportin-1 (XPO1) in the oncogenesis of several malignancies, and there is emerging evidence that XPO1 inhibition is a key target against canc
Externí odkaz:
https://doaj.org/article/6ccf03c084ff4e41bec3b03f995422b6
Publikováno v:
Data in Brief, Vol 26, Iss , Pp - (2019)
In this work we present a novel set of possible auto-oligomerisation states of yeast protein Fzo1 in the context of membrane docking. The dataset reports atomistic models and trajectories derived from a molecular dynamics study of the yeast mitofusin
Externí odkaz:
https://doaj.org/article/7deee50ec6254ca5af157818b51d2e23
Autor:
Joohee Park, Antoine Taly, Jennifer Bourreau, Frédéric De Nardi, Claire Legendre, Daniel Henrion, Nathalie C. Guérineau, Christian Legros, César Mattei, Hélène Tricoire-Leignel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5106 (2021)
Neonicotinoid insecticides are nicotine-derived molecules which exert acute neurotoxic effects over the insect central nervous system by activating nicotinic acetylcholine receptors (nAChRs). However, these receptors are also present in the mammalian
Externí odkaz:
https://doaj.org/article/99ca2ba9bb954f93804b2d123dc65ed3