Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Antoine R. Ramjaun"'
Autor:
Martin Wagner, Patricia H. Warne, Julian Downward, Kenneth Ryder, Patrick Michl, Corrado D'Arrigo, Andre Menke, Olivier E. Pardo, Richard Poulsom, Thomas M. Gress, Antoine R. Ramjaun
Publikováno v:
Cancer Cell. 7:521-532
SummaryCUTL1, also known as CDP, Cut, or Cux-1, is a homeodomain transcriptional regulator known to be involved in development and cell cycle progression. Here we report that CUTL1 activity is associated with increased migration and invasiveness in n
Autor:
Frédéric Checler, Antoine R. Ramjaun, Paula A.G. Garrido, Alain Beaudet, Franck Vandenbulcke, Emer S. Ferro, Bruno Vincent
Publikováno v:
DNA and Cell Biology. 18:323-331
Thimet oligopeptidase (EC 3.4.24.15; EP24.15) and neurolysin (EC 3.4.24.16; EP24.16) are closely related enzymes involved in the metabolic inactivation of bioactive peptides. Both of these enzymes were previously shown to be secreted from a variety o
Publikováno v:
FEBS Letters. 414:308-312
Amphiphysin I and II are nerve terminal-enriched proteins thought to function in synaptic vesicle endocytosis. In addition to a C-terminal SH3 domain, the proteins contain a highly conserved putative SH3 binding site and numerous consensus phosphoryl
Autor:
Kairbaan Hodivala-Dilke, Marianne Baker, Louise E. Reynolds, Madeline Parsons, Dylan T. Jones, Ian R. Hart, Graeme M. Birdsey, Anna M. Randi, Delphine M. Lees, Bernardo Tavora, Antoine R. Ramjaun, Vassiliki Kostourou, Tanguy Lechertier, Stephen D. Robinson
Publikováno v:
Nature communications
Kostourou, V, Lechertier, T, Reynolds, L E, Lees, D M, Baker, M, Jones, D T, Tavora, B, Ramjaun, A R, Birdsey, G M, Robinson, S D, Parsons, M, Randi, A M, Hart, I R & Hodivala-Dilke, K 2013, ' FAK-heterozygous mice display enhanced tumour angiogenesis ', Nature Communications, vol. 4, no. N/A, 2020 . https://doi.org/10.1038/ncomms3020
Scopus-Elsevier
Kostourou, V, Lechertier, T, Reynolds, L E, Lees, D M, Baker, M, Jones, D T, Tavora, B, Ramjaun, A R, Birdsey, G M, Robinson, S D, Parsons, M, Randi, A M, Hart, I R & Hodivala-Dilke, K 2013, ' FAK-heterozygous mice display enhanced tumour angiogenesis ', Nature Communications, vol. 4, no. N/A, 2020 . https://doi.org/10.1038/ncomms3020
Scopus-Elsevier
Genetic ablation of endothelial focal adhesion kinase (FAK) can inhibit pathological angiogenesis, suggesting that loss of endothelial FAK is sufficient to reduce neovascularization. Here we show that reduced stromal FAK expression in FAK-heterozygou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1486a4b8affdb899f94d88f6a8bd266c
http://hdl.handle.net/10044/1/73781
http://hdl.handle.net/10044/1/73781
Publikováno v:
The international journal of biochemistrycell biology. 41(3)
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is prevalent both during normal mammalian development and in certain pathological conditions such as tumor growth. It is stimulated and controlled by a complex network of
Autor:
Antoine R. Ramjaun, Julian Downward
Publikováno v:
Cell cycle (Georgetown, Tex.). 6(23)
Much progress has been made in understanding the myriad of intracellular signaling pathways responsible for control of cell physiology. Signalling downstream of receptor tyrosine kinases (RTKs) is probably the most studied signalling mechanism to dat
Autor:
Paula Haiko, Gordon Stamp, Kari Alitalo, Antoine R. Ramjaun, Emma Nye, Barbara Nicke, Yihua Wang, Julian Downward, Surbhi Gupta, Patricia H. Warne
Publikováno v:
Cell. 129(5)
Ras proteins signal through direct interaction with a number of effector enzymes, including type I phosphoinositide (PI) 3-kinases. Although the ability of Ras to control PI 3-kinase has been well established in manipulated cell culture models, evide
Publikováno v:
The Journal of biological chemistry. 279(12)
Endophilin A1 is an SH3 domain-containing protein functioning in membrane trafficking on the endocytic pathway. We have identified the E3 ubiquitin ligase itch/AIP4 as an endophilin A1-binding partner. Itch belongs to the Nedd4/Rsp5p family of protei
Autor:
Annie Angers, Valerie Legendre-Guillemin, Antoine R. Ramjaun, Peter S. McPherson, Xin-Kang Tong
Publikováno v:
The Journal of biological chemistry. 276(31)
The endophilin family of proteins function in clathrin-mediated endocytosis. Here, we have identified and cloned the rat germinal center kinase-like kinase (rGLK), a member of the GCK (germinal center kinase) family of c-Jun N-terminal kinase (JNK) a
Publikováno v:
The Journal of biological chemistry. 274(28)
Amphiphysin I and II are nerve terminal-enriched proteins containing SH3 domains that interact with dynamin and synaptojanin. The amphiphysins may function in synaptic vesicle endocytosis by targeting synaptojanin and dynamin to emerging endocytic bu