Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.

Autor: Olivier Cases, Antoine Joseph, Antoine Obry, Mathieu D Santin, Sirine Ben-Yacoub, Michel Pâques, Sabine Amsellem-Levera, Ana Bribian, Manuel Simonutti, Sébastien Augustin, Thomas Debeir, José Alain Sahel, Annabel Christ, Fernando de Castro, Stéphane Lehéricy, Pascal Cosette, Renata Kozyraki

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129518 (2015)

Myopia is a common ocular disorder generally due to increased axial length of the eye-globe. Its extreme form high myopia (HM) is a multifactorial disease leading to retinal and scleral damage, visual impairment or loss and is an important health iss

Externí odkaz: https://doaj.org/article/7cb50aef3a594c39b4e88744e38346f4

Impact of chlorhexidine digluconate and temperature on curli production in Escherichia coli—consequence on its adhesion ability

Autor: Laurence Mora, Ali Othmane, Laurent Coquet, Julie Hardouin, Thierry Jouenne, Antoine Obry, Nabil Borghol

Publikováno v: AIMS Microbiology. 3:915-937

Chlorhexidine-Digluconate (CHX-Dg) is a biocide widely used as disinfectant or antiseptic in clinical and domestic fields. It is often found in the formulation of solutions to treat superficial wounds. Nevertheless, few studies have focused on its ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fd27fbddc86efd0a8d55aa6fffc77d3
https://doi.org/10.3934/microbiol.2017.4.915

Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice

Autor: Pascal Cosette, Sébastien Augustin, Sirine Ben-Yacoub, Antoine Obry, Manuel Simonutti, Géraldine Toutirais, Renata Kozyraki, Olivier Cases, Antoine Joseph, Annabel Christ

Publikováno v: Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2017, 1863 (6), pp.1242-1254. ⟨10.1016/j.bbadis.2017.03.022⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2017, 1863 (6), pp.1242-1254. ⟨10.1016/j.bbadis.2017.03.022⟩
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2017, 1863 (6), pp.1242-1254. ⟨10.1016/j.bbadis.2017.03.022⟩

International audience; High myopia (HM) is one of the main causes of visual impairment and blindness all over the world and an unsolved medical problem. Persons with HM are predisposed to other eye pathologies such as retinal detachment, myopic reti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c61c7d7d5366472ac000a390975680
https://doi.org/10.1016/j.bbadis.2017.03.022

Overexpression of MHC class I in muscle of lymphocyte-deficient mice causes a severe myopathy with induction of the unfolded protein response

Autor: François-Jérôme Authier, Olivier Boyer, Laurent Drouot, Manuel Fréret, Claire Dauly, Pascal Cosette, Antoine Obry, Sandra Ahmed-Lacheheb, Sahil Adriouch

Publikováno v: The American journal of pathology. 183(3)

Muscle fibers do not normally express major histocompatibility complex class I (MHC-I) molecules, and their reexpression is a hallmark of inflammatory myopathies. It has been shown in mice that overexpression of MHC-I induces a poorly inflammatory my

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88643de56fc1a8744c6582bb22bf748d
https://pubmed.ncbi.nlm.nih.gov/23850081

Identification of a set of eight proteins able to predict the response to methotrexate/etanercept in rheumatoid arthritis patients

Autor: P. Morel, Pascal Cosette, P. Fardellone, P Chan Tchi Tsong, C Dauly, R.M. Flipo, X. Le Loët, Olivier Vittecoq, Antoine Obry, Thierry Lequerré, J Siemowski, Olivier Boyer, Christian Marcelli

Publikováno v: Annals of the Rheumatic Diseases. 71:A88.2-A89

Background The number of biologic agents in rheumatoid arthritis (RA) is continuously increasing. However, clinicians observe that around 30–40% of treated patients fail to respond to tumour necrosis factor α blocking agents. One way to optimise t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b7252b5401f9074cf7e4e9b9bfa9b5d
https://doi.org/10.1136/annrheumdis-2011-201239.8