Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Antoine Menoret"'
Autor:
Crystal Morales Del Valle, Joseph R. Maxwell, Maria M. Xu, Antoine Menoret, Payal Mittal, Naomi Tsurutani, Adam J. Adler, Anthony T. Vella
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1434-1445.e3 (2019)
Summary: Chronic exposure to tumor-associated antigens inactivates cognate T cells, restricting the repertoire of tumor-specific effector T cells. This problem was studied here by transferring TCR transgenic CD4 T cells into recipient mice that const
Externí odkaz:
https://doaj.org/article/942b5316a64a413e811e6982067fb4b9
Autor:
Daniel W. Rosenberg, Anthony T. Vella, David C. Montrose, Shingo Miyamoto, Takuji Tanaka, Antoine Menoret, Masako Nakanishi
PDF file - 1.84 MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8733e7ca38a39143bf8b479f6fe63d62
https://doi.org/10.1158/1940-6207.22524332.v1
https://doi.org/10.1158/1940-6207.22524332.v1
Autor:
Pearl A. Sutter, Cory M. Willis, Antoine Menoret, Alexandra M. Nicaise, Anthony Sacino, Arend. H. Sikkema, Evan Jellison, Kyaw K. Win, David K. Han, William Church, Wia Baron, Anthony T. Vella, Stephen J. Crocker
Publikováno v:
bioRxiv
Astrocyte activation is associated with neuropathology and the production of tissue inhibitor of metalloproteinase-1 (TIMP1). TIMP1 is a pleiotropic extracellular protein that functions both as a protease inhibitor and as a growth factor. We have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16abc3721668b894d532a6440c9706f
https://europepmc.org/articles/PMC9949145/
https://europepmc.org/articles/PMC9949145/
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The search for dementia treatments, including treatments for neuropsychiatric lupus (NPSLE), has not yet uncovered useful therapeutic targets that mitigate underlying inflammation. Currently, NPSLE’s limited treatment options are often acc
Externí odkaz:
https://doaj.org/article/25e88789dddd4480a02f0d67db2b4f57
Autor:
Jessica Hensel, Sarah-Anne Nicholas, Omar Omar, Amy Kimble, Arjun Nagpal, Antoine Menoret, Evan R Jellison, Annabelle Rodriguez, Manabu Ozawa, Anthony Vella, Patrick A Murphy
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
NFκB mediated endothelial activation drives leukocyte recruitment and atherosclerosis, in part through upregulation of adhesion molecules Icam1 and Vcam. The endothelium is primed for cytokine activation of NFκB by exposure to low and disturbed blo
Publikováno v:
The Journal of Immunology. 208:55.11-55.11
Boosting T cell activation through costimulation directs defense against cancer and viral infections. Despite many studies targeting costimulation in clinical trials, the increased potency and reprogramming of T cells endowed by costimulation is poor
Autor:
William C. Theune, Ju Chen, Eileen Victoria Theune, Xiaoyang Ye, Antoine Ménoret, Anthony T. Vella, Kepeng Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundInterleukin-17 (IL-17) family cytokines promote protective inflammation for pathogen resistance, but also facilitate autoimmunity and tumor development. A direct signal of IL-17 to regulatory T cells (Tregs) has not been reported and may he
Externí odkaz:
https://doaj.org/article/bf87f7da59524d10bc5a24ee0e7274b2
Autor:
Ashley Jean Russo, Swathy Vasudevan, Antoine Menoret, Shivalee Duduskar, Margaret Fettis, Chuan Li, Santiago Mendez Huergo, Puja Kumari, Karthik Chandran, Sivapriya Kailasan Vanaja, Michael Bauer, Christoph Sponholz, Gabriel Rabinovich, Gregory Hudalla, Anthony Vella, Sachin Deshmukh, Beiyan Zhou, Vijay Rathinam
Publikováno v:
The Journal of Immunology. 204:68.23-68.23
Activation of inflammatory caspases, such as caspase-11 and caspase-4, by lipopolysaccharide (LPS) from Gram-negative bacteria, is a key mechanism of innate immune defense against infections. This cytosolic LPS sensing pathway results in activation o
Autor:
Ashley Jean Russo, Antoine Menoret, Shivalee Duduskar, Gabriel Rabinovich, Sachin D Deshmukh, Anthony T Vella, Vijay Rathinam
Publikováno v:
The Journal of Immunology. 202:126.36-126.36
Sepsis is a life-threatening disease caused by the immune system’s response to infection that results in excessive inflammation, organ damage and often death. In fact, sepsis is the leading cause of death in intensive care units and is responsible
Autor:
Vijay Rathinam, Ashley Russo, Antoine Menoret, Gabriel Rabinovich, Shivalee Duduskar, Sachin Deshmukh, Anthony T Vella
Publikováno v:
The Journal of Immunology. 202:63.14-63.14
Intracellular sensing of LPS by inflammatory caspases such as caspase-11 has emerged as a key mechanism of innate immune activation during Gram-negative bacterial infections. Cytosolic recognition of LPS by caspase-11 leads to inflammatory cell death