Stereotyped spatial patterns of functional synaptic connectivity in the cerebellar cortex

Autor: Antoine M Valera, Francesca Binda, Sophie A Pawlowski, Jean-Luc Dupont, Jean-François Casella, Jeffrey D Rothstein, Bernard Poulain, Philippe Isope

Publikováno v: eLife, Vol 5 (2016)

Motor coordination is supported by an array of highly organized heterogeneous modules in the cerebellum. How incoming sensorimotor information is channeled and communicated between these anatomical modules is still poorly understood. In this study, w

Externí odkaz: https://doaj.org/article/fecce531808b42f48ff88f06ee8abd0d

Precompensation of 3D field distortions in remote focus two-photon microscopy

Autor: R. Angus Silver, Antoine M. Valera, John E. Mitchell, Paul Anthony Kirkby, Fiona C. Neufeldt

Publikováno v: Biomedical Optics Express

Remote focusing is widely used in 3D two-photon microscopy and 3D photostimulation because it enables fast axial scanning without moving the objective lens or specimen. However, due to the design constraints of microscope optics, remote focus units a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f1b6f98b6202ae06962bbbab0b50f0
http://arxiv.org/abs/2103.10499

Cerebellar Modules and Their Role as Operational Cerebellar Processing Units

Autor: Martijn Schonewille, Douglas R. Wylie, Philippe Isope, Tom J. H. Ruigrok, Amanda M Brown, Charlotte Lawrenson, Elizabeth P. Lackey, Richard Apps, Jan Voogd, Bridget M. Lumb, Roy V. Sillitoe, Sho Aoki, Ludovic Spaeth, Timothy J. Ebner, Richard Hawkes, Henrik Jörntell, Izumi Sugihara, Fredrik Bengtsson, Gang Chen, Antoine M. Valera

Publikováno v: The Cerebellum
The Cerebellum, Springer, 2018, 17 (5), pp.654-682. ⟨10.1007/s12311-018-0952-3⟩
Cerebellum (London, England)
The Cerebellum, Taylor & Francis Ltd., 2018, 17 (5), pp.654-682. ⟨10.1007/s12311-018-0952-3⟩
The Cerebellum, 17(5), 654-682. Springer New York
Apps, R, Hawkes, R, Aoki, S, Bengtsson, F, Brown, A M, Chen, G, Ebner, T J, Isope, P, Jörntell, H, Lackey, E P, Lawrenson, C, Lumb, B, Schonewille, M, Sillitoe, R V, Spaeth, L, Sugihara, I, Valera, A, Voogd, J, Wylie, D R & Ruigrok, T J H 2018, ' Cerebellar Modules and Their Role as Operational Cerebellar Processing Units ', Cerebellum . https://doi.org/10.1007/s12311-018-0952-3

The compartmentalization of the cerebellum into modules is often used to discuss its function. What, exactly, can be considered a module, how do they operate, can they be subdivided and do they act individually or in concert are only some of the key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970ca1d3d684fdf0a31ce9fdd540ba8c
https://hal-cnrs.archives-ouvertes.fr/hal-02400531/file/Apps2018_Article_CerebellarModulesAndTheirRoleA.pdf

A frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity

Autor: Bernard Poulain, Hartmut Schmidt, Kevin Dorgans, Antoine M. Valera, Frédéric Doussau, Philippe Isope

The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pool which are differentially poised for exocytosis shapes short-term plasticity at depressing synapses. Here, we used in vitro recording and modeling of synaptic activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f605b2fbb28033a2cb85ac20a1c34f2f
https://doi.org/10.1101/146753

Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge

Autor: Clément Léna, Daniela Popa, Fekrije Selimi, Vanessa Gautheron, Nicolas Guyon, Stéphane Dieudonné, Jean-Christophe Cassel, Frédéric Doussau, Joseph Chaumont, Guillaume P. Dugué, Jean-Luc Dupont, Bernard Poulain, Aline Stephan, Antoine M. Valera, Philippe Isope, Païkan Marcaggi, Michel Barrot, Sophie Reibel-Foisset

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (40), pp.16223-16228. ⟨10.1073/pnas.1302310110⟩

Climbing fibers, the projections from the inferior olive to the cerebellar cortex, carry sensorimotor error and clock signals that trigger motor learning by controlling cerebellar Purkinje cell synaptic plasticity and discharge. Purkinje cells target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7074f4286299e7e183624ef36822e611
https://doi.org/10.1073/pnas.1302310110