Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Antoine Kichler"'
Autor:
Victor Lehot, Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Igor Dovgan, Sylvain Ursuegui, Sarah Cianférani, Antoine Kichler, Guilhem Chaubet, Alain Wagner
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1643 (2023)
Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is of
Externí odkaz:
https://doaj.org/article/3b1c23f633864d7a9b898ed3a61b0eff
Autor:
Conor McCartin, Juliette Blumberger, Candice Dussouillez, Patricia Fernandez de Larrinoa, Monique Dontenwill, Christel Herold-Mende, Philippe Lavalle, Béatrice Heurtault, Stéphane Bellemin-Laponnaz, Sylvie Fournel, Antoine Kichler
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 1, p 17 (2022)
Cationic polymers such as polyethylenimine (PEI) have found a pervasive place in laboratories across the world as gene delivery agents. However, their applications are not limited to this role, having found a place as delivery agents for drugs, in co
Externí odkaz:
https://doaj.org/article/962abe61aa1a417e8a03750be30437e2
Autor:
Lorène Tallet, Emilie Frisch, Mégane Bornerie, Claire Medemblik, Benoît Frisch, Philippe Lavalle, Gilles Guichard, Céline Douat, Antoine Kichler
Publikováno v:
Molecules, Vol 27, Iss 5, p 1749 (2022)
There is an urgent need to develop new therapeutic strategies to fight the emergence of multidrug resistant bacteria. Many antimicrobial peptides (AMPs) have been identified and characterized, but clinical translation has been limited partly due to t
Externí odkaz:
https://doaj.org/article/de093bcfb9fe49988b72c4705e47d313
Different Biological Activities of Histidine-Rich Peptides Are Favored by Variations in Their Design
Publikováno v:
Toxins, Vol 13, Iss 5, p 363 (2021)
The protein transduction and antimicrobial activities of histidine-rich designer peptides were investigated as a function of their sequence and compared to gene transfection, lentivirus transduction and calcein release activities. In membrane environ
Externí odkaz:
https://doaj.org/article/1997e35c0d4f45b5a6538ce8ac6d07c9
Autor:
David Fenard, Dina Ingrao, Ababacar Seye, Julien Buisset, Sandrine Genries, Samia Martin, Antoine Kichler, Anne Galy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Gene transfer into hCD34+ hematopoietic stem/progenitor cells (HSCs) using human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors (LVs) has several promising therapeutic applications. Yet, efficiency, safety, and cost of LV gene therapy
Externí odkaz:
https://doaj.org/article/e392f8866970436db36cede8926c7a9f
Autor:
Xavier Gerard, Isabelle Perrault, Sylvain Hanein, Eduardo Silva, Karine Bigot, Sabine Defoort-Delhemmes, Marlèene Rio, Arnold Munnich, Daniel Scherman, Josseline Kaplan, Antoine Kichler, Jean-Michel Rozet
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Leber congenital amaurosis (LCA) is a severe hereditary retinal dystrophy responsible for congenital or early-onset blindness. The most common disease-causing mutation (>10%) is located deep in intron 26 of the CEP290 gene (c.2991+1655A>G). It create
Externí odkaz:
https://doaj.org/article/4c6ac99f7bf04c2eb9a5d0e5fd83e9c1
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15576 (2010)
BackgroundAdeno-associated virus has attracted great attention as vehicle for body-wide gene delivery. However, for the successful treatment of a disease such as Duchenne muscular dystrophy infusion of very large amounts of vectors is required. This
Externí odkaz:
https://doaj.org/article/f1de877734aa451f83ba586ae2ea074a
Autor:
Wagner, Victor Lehot, Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Igor Dovgan, Sylvain Ursuegui, Sarah Cianférani, Antoine Kichler, Guilhem Chaubet, Alain
Publikováno v:
Pharmaceutics; Volume 15; Issue 6; Pages: 1643
Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is of
Autor:
Maria Vittoria Spanedda, Marcella De Giorgi, Béatrice Heurtault, Antoine Kichler, Line Bourel-Bonnet, Benoît Frisch
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629536
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee8617e2258ecf334c974edc35eb94f4
https://doi.org/10.1007/978-1-0716-2954-3_15
https://doi.org/10.1007/978-1-0716-2954-3_15
Autor:
Conor McCartin, Eric Mathieu, Monique Dontenwill, Christel Herold-Mende, Ahmed Idbaih, Anna Bonfiglio, Matteo Mauro, Sylvie Fournel, Antoine Kichler
Cancer stem cells (CSCs) represent a difficult to treat cellular niche within tumours due to their unique characteristics, which give them a high propensity for resistance to classical anti-cancer treatments and the ability to re-populate the tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe86d03632c17b159991ec9bc2b407fd
https://linkinghub.elsevier.com/retrieve/pii/S0009279722003726
https://linkinghub.elsevier.com/retrieve/pii/S0009279722003726