Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Antoine Dufour"'
Autor:
Nicole L. Rosin, Tara M. L. Winstone, Margaret Kelley, Jeff Biernaskie, Antoine Dufour, Dennis J. Orton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Collagen is the most abundant protein in mammals and a major structural component of the extracellular matrix (ECM). Changes to ECM composition occur as a result of numerous physiological and pathophysiological causes, and a common means to
Externí odkaz:
https://doaj.org/article/be1493e152b24c85b6b6a2cbf28b0991
Autor:
Patrizia Leone, Eleonora Malerba, Marcella Prete, Antonio Giovanni Solimando, Giorgio Alberto Croci, Paolo Ditonno, Marco Tucci, Nicola Susca, Afshin Derakhshani, Antoine Dufour, Valli De Re, Nicola Silvestris, Vito Racanelli
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background Activation of CD28 on multiple myeloma (MM) plasma cells, by binding to CD80 and CD86 on dendritic cells, decreases proteasome subunit expression in the tumor cells and thereby helps them evade being killed by CD8+ T cells. Unders
Externí odkaz:
https://doaj.org/article/7813f36d6cc1412998d9de3a30416ef1
Autor:
Ejaife O. Agbani, Daniel Young, Si An Chen, Sophie Smith, Adrienne Lee, Alastair W. Poole, Antoine Dufour, Man-Chiu Poon
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background The Montreal platelet syndrome kindred (MPS) with VWF p.V1316M mutation (2B-VWDMPS) is an extremely rare disorder. It has been associated with macrothrombocytopenia, spontaneous platelet clumping, mucocutaneous, and other bleeding
Externí odkaz:
https://doaj.org/article/57f3e9bbe2d9459d9003041ef4514fd5
Autor:
Roman J. Krawetz, Leila Larijani, Jessica May Corpuz, Nicoletta Ninkovic, Nabangshu Das, Alexandra Olsen, Nicholas Mohtadi, Alexander Rezansoff, Antoine Dufour
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Osteoarthritis (OA) is a chronic debilitating disease impacting a significant percentage of the global population. While there are numerous surgical and non-invasive interventions that can postpone joint replacement, there are no
Externí odkaz:
https://doaj.org/article/f0e94d7d37bb452a82633e24c25869b6
Autor:
Nabangshu Das, Luiz G. N. de Almeida, Afshin Derakhshani, Daniel Young, Kobra Mehdinejadiani, Paul Salo, Alexander Rezansoff, Gregory D. Jay, Christian P. Sommerhoff, Tannin A. Schmidt, Roman Krawetz, Antoine Dufour
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Altered expression and function of the extracellular matrix protein PRG4 have been associated with osteoarthritis. Here, the authors show that mast cell tryptase β cleaves PRG4, resulting in a reduction of lubrication and activation of inflammation
Externí odkaz:
https://doaj.org/article/acd1e0dd071f4882af74316106133957
Autor:
Ravi Holani, Chathurika Rathnayaka, Graham A.D. Blyth, Anshu Babbar, Priyoshi Lahiri, Daniel Young, Antoine Dufour, Morley D. Hollenberg, Derek M. McKay, Eduardo R. Cobo
Publikováno v:
Journal of Innate Immunity, Pp 1-18 (2022)
Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood. Herein, analyses with the attaching/effacin
Externí odkaz:
https://doaj.org/article/ba4d2e7029b243e9afdccaf552cfcee9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The colonic mucus bilayer is the first line of innate host defense that at the same time houses and nourishes the commensal microbiota. The major components of mucus secreted by goblet cells are MUC2 mucin and the mucus-associated protein, FCGBP (IgG
Externí odkaz:
https://doaj.org/article/720f84378b0f47b0bf7e7366cc5873f7
Autor:
Lisa Gamsjäger, Karina M. Cirone, Steffany Schluessel, Mackenzie Campsall, Aydin Herik, Priyoshi Lahiri, Daniel Young, Antoine Dufour, Panagiotis Sapountzis, Saria Otani, Diego E. Gomez, M. Claire Windeyer, Eduardo R. Cobo
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionCalves are highly susceptible to gastrointestinal infection with Cryptosporidium parvum (C. parvum), which can result in watery diarrhea and eventually death or impaired development. With little to no effective therapeutics, understanding
Externí odkaz:
https://doaj.org/article/1bc03cea11c541a2afb7c5cce34a8cca
Publikováno v:
Animal Microbiome, Vol 4, Iss 1, Pp 1-17 (2022)
Abstract Background Eukaryotic microbes can modulate mammalian host health and disease states, yet the molecular contribution of gut fungi remains nascent. We previously showed that mice exclusively colonised with fungi displayed increased sensitivit
Externí odkaz:
https://doaj.org/article/7cf3a346dc534511bf13c8b65886214f
Autor:
Veronika Kuchařová Pettersen, Luis Caetano Martha Antunes, Antoine Dufour, Marie-Claire Arrieta
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 274-286 (2022)
Humans have a long-standing coexistence with microorganisms. In particular, the microbial community that populates the human gastrointestinal tract has emerged as a critical player in governing human health and disease. DNA and RNA sequencing techniq
Externí odkaz:
https://doaj.org/article/b4b89d3027734936b78cc6b4d89c5c0b