Výsledky vyhledávání - "Antoine Dardenne"

Prédispositions génétiques au cancer gastrique et leur association au type histologique

Autor: Antoine Dardenne, Laura Sirmai, Julie Metras, Diana Enea, Magali Svrcek, Patrick R. Benusiglio

Publikováno v: Bulletin du Cancer. 110:512-520

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::adecd06b20057df50a2d493da234d20c
https://doi.org/10.1016/j.bulcan.2022.06.010

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BRAF V600E/RAS Mutations and Lynch Syndrome in Patients With MSI-H/dMMR Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors

Autor: Raphael Colle, Sara Lonardi, Marine Cachanado, Michael J Overman, Elena Elez, Marwan Fakih, Francesca Corti, Priya Jayachandran, Magali Svrcek, Antoine Dardenne, Baptiste Cervantes, Alex Duval, Romain Cohen, Filippo Pietrantonio, Thierry André

Publikováno v: The Oncologist.

Background We pooled data from 2 cohorts of immune checkpoint inhibitors-treated microsatellite instability-high/mismatch repair-deficient (MSI/dMMR) metastatic colorectal cancer patients to evaluate the prognostic value of RAS/BRAFV600E mutations an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c88f6e7935ab7dc17c08dd5aa8b426a6
https://doi.org/10.1093/oncolo/oyad082

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Feasibility, safety and efficacy of human intra-tumoral immuno-therapy. Gustave Roussy's initial experience with its first 100 patients

Publikováno v: European journal of cancer (Oxford, England : 1990). 172

Many intratumoural (IT) immunotherapies are currently developed in the clinic with the aim of overcoming primary and secondary resistance and/or to limit on-target/off-tumour toxicities of immune checkpoint targeted therapies. This study aimed to des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1716ffaeda8e5e522837246cd3e00b
https://pubmed.ncbi.nlm.nih.gov/35724442

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Impact of Lynch syndrome, BRAFV600E, and RAS mutations on outcomes in MSI/dMMR metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors (ICI): Analysis of combined international cohorts

Autor: Raphael Colle, Sara Lonardi, Marine Cachanado, Michael J. Overman, Elena Elez, Marwan Fakih, Francesca Corti, Priya Jayachandran, Magali Svrcek, Antoine Dardenne, Alex Duval, Romain Cohen, Filippo Pietrantonio, Thierry Andre

Publikováno v: Journal of Clinical Oncology. 41:171-171

171 Background: ICI have demonstrated efficacy in patients (pts) with MSI/dMMR mCRC . Lynch (LS) vs sporadic (Sp) status, BRAFV600E and RAS mutations (mt) are known factors of clinical and molecular heterogeneity in this population. We aimed to evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e051586947b4e4af6925736ae7d5dc42
https://doi.org/10.1200/jco.2023.41.4_suppl.171

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Beyond the concept of cold and hot tumors for the development of novel predictive biomarkers and the rational design of immunotherapy combination

Autor: Antonin Saldmann, Lea Paolini, Céleste Lebbé, Eléonore De Guillebon, Sylvie Séguier, Antoine Dardenne, Thi Anh-Dao Tran, Eric Tartour

Publikováno v: International journal of cancerReferences. 147(6)

Immunotherapy has revolutionized the management of cancers. At the end of 2018, 1,716 clinical trials assessed regimen that combine program death-1 (PD-1)/program death ligand-1 (PD-L1) blockers with other cancer therapies (tyrosine kinase inhibitor,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57db7c7af844b97f36c6faa09924a18
https://pubmed.ncbi.nlm.nih.gov/31997345

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