Human Ubiquitin-Specific Peptidase 18 Is Regulated by microRNAs via the 3'Untranslated Region, A Sequence Duplicated in Long Intergenic Non-coding RNA Genes Residing in chr22q11.21

Autor: Erminia Rubino, Melania Cruciani, Nicolas Tchitchek, Anna Le Tortorec, Antoine D. Rolland, Önay Veli, Leslie Vallet, Giulia Gaggi, Frédérique Michel, Nathalie Dejucq-Rainsford, Sandra Pellegrini

Publikováno v: Frontiers in Genetics, Vol 11 (2021)

Ubiquitin-specific peptidase 18 (USP18) acts as gatekeeper of type I interferon (IFN) responses by binding to the IFN receptor subunit IFNAR2 and preventing activation of the downstream JAK/STAT pathway. In any given cell type, the level of USP18 is

Externí odkaz: https://doaj.org/article/b448cf2f9988430391a12e4d7dd91174

MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian Follicles

Autor: Marina G. Yefimova, Celia Ravel, Antoine D. Rolland, Nicolas Bourmeyster, Bernard Jégou

Publikováno v: Cells, Vol 10, Iss 6, p 1443 (2021)

Timely and efficient elimination of apoptotic substrates, continuously produced during one’s lifespan, is a vital need for all tissues of the body. This task is achieved by cells endowed with phagocytic activity. In blood-separated tissues such as

Externí odkaz: https://doaj.org/article/13c348098e6148d88d10af436f4bcda4

Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole

Autor: Indusha Kugathas, Hanna K. L. Johansson, Edith Chan Sock Peng, Maryne Toupin, Bertrand Evrard, Thomas A. Darde, Julie Boberg, Monica K. Draskau, Antoine D. Rolland, Séverine Mazaud-Guittot, Frédéric Chalmel, Terje Svingen

Publikováno v: Kugathas, I, Johansson, H K L, Chan Sock Peng, E, Toupin, M, Evrard, B, Darde, T A, Boberg, J, Draskau, M K, Rolland, A D, Mazaud-Guittot, S, Chalmel, F & Svingen, T 2023, ' Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole ', Archives of Toxicology, vol. 97, pp. 849-863 . https://doi.org/10.1007/s00204-023-03442-2
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩

Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are not sensitive enou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc064d00a0564016fb619e64450e33a
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671

Profiling of androgen response in rainbow trout pubertal testis: relevance to male gonad development and spermatogenesis.

Autor: Antoine D Rolland, Aurélie Lardenois, Anne-Sophie Goupil, Jean-Jacques Lareyre, Rémi Houlgatte, Frédéric Chalmel, Florence Le Gac

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e53302 (2013)

The capacity of testicular somatic cells to promote and sustain germ cell differentiation is largely regulated by sexual steroids and notably androgens. In fish species the importance of androgens is emphasized by their ability to induce sex reversal

Externí odkaz: https://doaj.org/article/e8fc4c83403a49daba66abc968a91fe8

CLPH, a Novel Casein Kinase 2-Phosphorylated Disordered Protein, Is Specifically Associated with Postmeiotic Germ Cells in Rat Spermatogenesis.

Autor: Pierre Calvel, Christine Kervarrec, Régis Lavigne, Virginie Vallet-Erdtmann, Myriam Guerrois, Antoine D. Rolland, Frédéric Chalmel, Bernard Jégou, Charles Pineau

Publikováno v: Journal of Proteome Research; Jun2009, Vol. 8 Issue 6, p2953-2965, 13p