Structural and Functional Mapping of Mesenchymal Bodies

Autor: Sébastien Sart, Raphaël Tomasi, Antoine Barizien, Gabriel Amselem, Ana Cumano, Charles Baroud

Publikováno v: Bio-Protocol, Vol 11, Iss 19 (2021)

The formation of spheroids with mesenchymal stem/stromal cells (MSCs), mesenchymal bodies (MBs), is usually performed using bioreactors or conventional well plates. While these methods promote the formation of a large number of spheroids, they provid

Externí odkaz: https://doaj.org/article/f8b8f98ddc3345c798416868b08c4d04

Mapping the structure and biological functions within mesenchymal bodies using microfluidics

Autor: Ana Cumano, Charles N. Baroud, Sébastien Sart, Antoine Barizien, Raphaël F.-X. Tomasi, Gabriel Amselem

Publikováno v: Science Advances
Science Advances, 2020, 6 (10), pp.eaaw7853. ⟨10.1126/sciadv.aaw7853⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (10), pp.eaaw7853. ⟨10.1126/sciadv.aaw7853⟩

MSC spheroids self-organize in a hierarchical manner, resulting in a spatial patterning of the function of individual cells.
Organoids that recapitulate the functional hallmarks of anatomic structures comprise cell populations able to self-organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db91d1fec39eef7ac077182e4a2edb89
https://hal-pasteur.archives-ouvertes.fr/pasteur-02641655

Growing from a few cells: combined effects of initial stochasticity and cell-to-cell variability

Autor: M. S. Suryateja Jammalamadaka, Charles N. Baroud, Antoine Barizien, Gabriel Amselem

Publikováno v: Journal of the Royal Society Interface
Journal of the Royal Society Interface, 2019, 16 (153), pp.20180935. ⟨10.1098/rsif.2018.0935⟩
Journal of the Royal Society Interface, the Royal Society, 2019, 16 (153), pp.20180935. ⟨10.1098/rsif.2018.0935⟩

The growth of a cell population from a large inoculum appears deterministic, although the division process is stochastic at the single-cell level. Microfluidic observations, however, display wide variations in the growth of small populations. Here we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a4066e1f3c6f6f0b0c26a1da57ff22
https://hal-pasteur.archives-ouvertes.fr/pasteur-03328787

Model for the erosion onset of a granular bed sheared by a viscous fluid

Autor: Le Yan, Antoine Barizien, Matthieu Wyart

Publikováno v: Physical Review E. 93

We study theoretically the erosion threshold of a granular bed forced by a viscous fluid. We first introduce a novel model of interacting particles driven on a rough substrate. It predicts a continuous transition at some threshold forcing $\theta_c$,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2974b1e1fd12bde62f2083dd2667b8fa
https://doi.org/10.1103/physreve.93.012903