PHACTR1 and APOC1 genetic variants are associated with multi-vessel coronary artery disease

Autor: Cynthia Al Hageh, Siobhán O’Sullivan, Andreas Henschel, Antoine Abchee, Mireille Hantouche, Nantia Iakovidou, Taly Issa, Stephanie Chacar, Moni Nader, Pierre A. Zalloua

Publikováno v: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024)

Abstract Background Severe coronary artery disease (CAD) represents an advanced arterial narrowing, often associated with critical complications like myocardial infarction and angina. This study aimed to comprehensively investigate determinants of se

Externí odkaz: https://doaj.org/article/e1aa329fe8e84b218e1f9ea7b9a0905f

Non-familial cardiomyopathies in Lebanon: exome sequencing results for five idiopathic cases

Autor: Marwan M. Refaat, Sylvana Hassanieh, Jad A. Ballout, Patrick Zakka, Mostafa Hotait, Athar Khalil, Fadi Bitar, Mariam Arabi, Samir Arnaout, Hadi Skouri, Antoine Abchee, Bernard Abi-Saleh, Maurice Khoury, Andreas Massouras, Georges Nemer

Publikováno v: BMC Medical Genomics, Vol 12, Iss 1, Pp 1-11 (2019)

Abstract Background Cardiomyopathies affect more than 0.5% of the general population. They are associated with high risk of sudden cardiac death, which can result from either heart failure or electrical abnormalities. Although different mechanisms un

Externí odkaz: https://doaj.org/article/714bffd2095d4d429574eb50cab5284a

Genome-wide association analysis of HDL-C in a Lebanese cohort.

Autor: Rebecca Deek, Jason Nasser, Anthony Ghanem, Marc Mardelli, Georges Khazen, Angelique K Salloum, Antoine Abchee, Michella Ghassibe-Sabbagh, Pierre Zalloua

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218443 (2019)

Low serum levels of high-density lipoprotein cholesterol (HDL-C) have been shown to be a risk factor for coronary artery disease independent of low-density lipoprotein cholesterol (LDL-C) in different populations. In this study, we investigated genet

Externí odkaz: https://doaj.org/article/9a2728b855cb41f1b446bf12b5ab5ded

Objective Assessment of Covid-19 Severity Affecting the Vocal and Respiratory System Using a Wearable, Autonomous Sound Collar

Autor: Georges Nassar, S. Bin, Antoine Abche, H. Aziz, Dany Ishac, Sandrine Matta, Elie Karam

Publikováno v: Cellular and Molecular Bioengineering
Cellular and Molecular Bioengineering, 2022, 15, pp.67-86. ⟨10.1007/s12195-021-00712-w⟩
Cellular and Molecular Bioengineering, Spinger (en ligne) / BMES (imprimé), In press, ⟨10.1007/s12195-021-00712-w⟩

Introduction Since the outbreak began in January 2020, Covid-19 has affected more than 161 million people worldwide and resulted in about 3.3 million deaths. Despite efforts to detect human infection with the virus as early as possible, the confirmat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce042c610ba89936f9b90cd75466094d
https://doi.org/10.1007/s12195-021-00712-w

Abstract 202: The R21C Mutation in Troponin I Has a Founder Effect in South Lebanon and Causes Malignant Hypertrophic Cardiomyopathy

Autor: Samir Arnaout, Mariam Arabi, Athar Khalil, Jonathan G. Seidman, Akl C. Fahed, Steven R. DePalma, Christine E. Seidman, Manal Batrawi, James S. Ware, Fadi Bitar, Georges Nemer, Antoine Abche, Barbara McDonough

Publikováno v: Circulation Research. 125

Hypertrophic Cardiomyopathy (HCM) occurs in 1 of every 500 people and has a wide phenotypic variability. In the majority of cases, HCM is caused by known mutations in genes that code for sarcomere proteins. Although gene testing is widely available f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edf8b9db823b46a612482b04429017c2
https://doi.org/10.1161/res.125.suppl_1.202