Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Antoine A. Noujaim"'
Autor:
Beatrice Leveugle, Richard B. Alexander, Antoine A. Noujaim, Kathleen A. Berlyn, Birgit Schultes, Dean L. Mann
Publikováno v:
Clinical Immunology. 101:276-283
Dendritic cells (DC) acquire antigens through a number of cell surface structures including receptors for the Fc portion of immunoglobulins and mannose. Little is known about the effects of antigen uptake via these receptors on antigen processing and
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 16:187-203
The murine monoclonal anti-CA125 antibody MAb-B43.13 has previously been administered as an immunoscintigraphic agent in order to monitor recurrence of ovarian cancer in patients, and a long-term follow-up demonstrated a survival benefit for these pa
Publikováno v:
Journal of Pharmaceutical Sciences. 87:1375-1378
The use of biodegradable poly(lactic-co-glycolic acid) (PLGA) microspheres as a cancer vaccine delivery system for induction of anti-idiotypic responses has been investigated using a single chain antibody scFv-pDL10, which recognizes the human ovaria
Publikováno v:
Cancer Immunology, Immunotherapy. 46:201-212
Intravenous injection of the murine monoclonal anti-CA125 antibody B43.13 (Ovarex: Ab1) into ovarian cancer patients led to the induction of an idiotypic network. Of the 75 patients who received one to ten injections of a 2-mg dose of the antibody, 4
Publikováno v:
Hybridoma. 16:41-45
Various immunological parameters were studied in 100 ovarian cancer patients injected with the OVAREX therapeutic vaccine (the functional component of which is anti-CA125 MAb-B43.13) to explain the serendipitous observation of prolonged survival afte
Autor:
F.T. Kreutz, David S. Wishart, Mavanur R. Suresh, Antoine A. Noujaim, D.C. Jette, Bruce A. Malcolm
Publikováno v:
Clinical Chemistry. 42:1961-1969
Prostate-specific antigen (PSA) is a widely used marker for screening and monitoring prostate cancer. We identified and characterized the epitopes of two anti-PSA monoclonal antibodies (mAbs) designated B80 and B87. The epitopes were initially mapped
Publikováno v:
Applied Radiation and Isotopes. 47:71-77
The covalent attachment of the bifunctional chelating agent 2-( p -aminobenzyl)-1,3-propanediamine-N,N,N′,N′-tetraacetic acid to proteins through a new linking arm containing an aldehyde function for the purpose of labeling proteins and monoclona
Autor:
James Diakur, Antoine A. Noujaim
Publikováno v:
Journal of Carbohydrate Chemistry. 13:777-797
The total synthesis of the tetrasaccharide sequence of the ganglioside GD3 (α-D-Neup5Ac-(2→8)-α-D-Neup5Ac-(2→3)-β-D-Galp-(1→4)-β-D-Glcp-) as the 4-methyl-3-pentenyl glycoside (13) has been accomplished in a relatively straightforward manner
Publikováno v:
Applied Radiation and Isotopes. 45:293-299
A method of quantitating stannous ion [Sn(II)] suitable for radiopharmaceutical kits, based on indirect iodometric titration, is described. The method is based on the oxidation of Sn(II) using a known excess of iodine and the excess unreacted iodine
Publikováno v:
Nuclear Medicine and Biology. 20:453-459
Two carbohydrates, N -acetylgalactosamine (GalNAc) and galactose-β -1,3-GalNAc have been attached to human IgG (hIgG) by a novel linking reagent, hexafluoroglutaric acid dimethyl ester. Fluorine-19 NMR signals were used for the determination of the