Zobrazeno 1 - 10
of 520
pro vyhledávání: '"Antoine Danchin"'
Autor:
Antoine Danchin
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 10, Pp 1888-1894 (2023)
Abstract Science is founded on a method based on critical thinking. A prerequisite for this is not only a sufficient command of language but also the comprehension of the basic concepts underlying our understanding of reality. This constraint implies
Externí odkaz:
https://doaj.org/article/1bba1c4cbae64bd19d6fef2c03f335c8
Autor:
Erhard Bremer, Alexandra Calteau, Antoine Danchin, Colin Harwood, John D. Helmann, Claudine Médigue, Bernhard O. Palsson, Agnieszka Sekowska, David Vallenet, Abril Zuniga, Cristal Zuniga
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 6, Pp 1203-1231 (2023)
Abstract The vast majority of genomic sequences are automatically annotated using various software programs. The accuracy of these annotations depends heavily on the very few manual annotation efforts that combine verified experimental data with geno
Externí odkaz:
https://doaj.org/article/6d5e102c8ead4c568a422a3bb01c5dde
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Thymidylate kinases (TMPKs) play an essential role in DNA biosynthesis across all domains of life by catalyzing dTMP phosphorylation to dTDP. In Pseudomonas putida KT2440, a model Gram-negative soil bacterium, tmk is disrupted by a 65-kb gen
Externí odkaz:
https://doaj.org/article/3028ca7db09342f291900aafd12e2812
Autor:
Antoine Danchin
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 1, Pp 42-64 (2022)
Summary Living systems are studied using three complementary approaches: living cells, cell‐free systems and computer‐mediated modelling. Progresses in understanding, allowing researchers to create novel chassis and industrial processes rest on a
Externí odkaz:
https://doaj.org/article/1913f61c8bdb428fa2436e03c9750acf
Autor:
Ida Lauritsen, Pernille Ott Frendorf, Silvia Capucci, Sophia A. H. Heyde, Sarah D. Blomquist, Sofie Wendel, Emil C. Fischer, Agnieszka Sekowska, Antoine Danchin, Morten H. H. Nørholm
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Microbial evolution often involves transient phenotypes and sequential development of multiple mutations of unclear relevance. Here, the authors show that the evolution of non-growing E. coli cells can be driven by alterations in pyrimidine nucleosid
Externí odkaz:
https://doaj.org/article/ddb79980ec96494cbf407a7e2b45ecb8
Autor:
Qing Pan, Zongjin Li, Xian Ju, Chaofan Hou, Yunzhu Xiao, Ruoping Shi, Chunxiang Fu, Antoine Danchin, Conghui You
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 3, Pp 1084-1106 (2021)
Summary How bacteria adjust gene expression to cope with variable environments remains open to question. Here, we investigated the way global gene expression changes in E. coli correlated with the metabolism of seven carbon substrates chosen to trigg
Externí odkaz:
https://doaj.org/article/1119107d4a9a430fb95cee49f6421698
Autor:
Antoine Danchin, André A. Fenton
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
The abstract basis of modern computation is the formal description of a finite state machine, the Universal Turing Machine, based on manipulation of integers and logic symbols. In this contribution to the discourse on the computer-brain analogy, we d
Externí odkaz:
https://doaj.org/article/700bb074b0fd4ad18a58b80cdf6cf69f
Autor:
Ye-Fan Hu, Jing-Chu Hu, Hua-Rui Gong, Antoine Danchin, Ren Sun, Hin Chu, Ivan Fan-Ngai Hung, Kwok Yung Yuen, Kelvin Kai-Wang To, Bao-Zhong Zhang, Thomas Yau, Jian-Dong Huang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
It has been reported that multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) including Alpha, Beta, Gamma, and Delta can reduce neutralization by antibodies, resulting in vaccine breakthrough infections.
Externí odkaz:
https://doaj.org/article/f3cd4e1825a3418ca89f77f950a187d6
Publikováno v:
Evolutionary Applications, Vol 13, Iss 8, Pp 1888-1905 (2020)
Abstract The probability D that a given clustered regularly interspaced short palindromic repeats (CRISPR)‐based gene drive element contaminates another, nontarget species can be estimated by the following Drive Risk Assessment Quantitative Estimat
Externí odkaz:
https://doaj.org/article/332bc841d7c444baa02a380cfc152743
Publikováno v:
Microbial Biotechnology, Vol 13, Iss 4, Pp 899-925 (2020)
Summary The translation process, central to life, is tightly connected to the one‐carbon (1‐C) metabolism via a plethora of macromolecule modifications and specific effectors. Using manual genome annotations and putting together a variety of expe
Externí odkaz:
https://doaj.org/article/302cb1f0413f4b9586f88f6013bc26da