Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Antje Wengner"'
Autor:
Stefan Gradl, Sooncheol Lee, Martin Lange, Xiaoyun Wu, Silvia Goldoni, Timothy Lewis, Charlotte Kopitz, Colin Garvie, Philip Lienau, Stephanie Hoyt, Henrik Seidel, Stephan Kaulfuss, Manuel Ellermann, Luc de Waal, Adrian Tersteegen, Sven Golfier, Detlev Suelzle, Christa Hegele-Hartung, James Carr, Frederick Brookfield, Michael Bruening, Melanie Berthold, Thibaud Jourdan, Monica Schenone, Galen Gao, Joseph McGaunn, Antje Wengner, Elisa Aquilanti, Franziska Siegel, Marine Garrido, Annette Walter, Isabelle Genvresse, Andrew Cherniack, Stuart Schreiber, Knut Eis, Ashley Eheim, Matthew Meyerson, Heidi Greulich
Publikováno v:
Cancer Research. 82:ND04-ND04
Velcrin compounds are a class of small molecules that induce complex formation between PDE3A and SLFN12, killing cancer cells that express elevated levels of these two proteins by a mechanism independent of PDE3A enzymatic inhibition. Instead, PDE3A
Autor:
Pascale Lejeune, Antje Wengner, Simon J. Baumgart, Ekaterina Nevedomskaya, Eva Corey, Dominik Mumberg, Bernard Haendler
Publikováno v:
Cancer Research. 79:924-924
Darolutamide is a structurally unique androgen receptor (AR) antagonist which has recently completed a pivotal clinical phase 3 trial. Here we explored the efficacy of darolutamide in different prostate cancer models and in combination with the ATR i
Publikováno v:
Microbiology. 151:835-840
A single gene cluster encoding components of a putative ATP-binding cassette (ABC) transporter for basic amino acids was identified in the incomplete genome sequence of the thermophilic Gram-positive bacteriumGeobacillus stearothermophilusbyblastsear
Publikováno v:
Archives of Biochemistry and Biophysics. 400:171-179
In living organisms a permanent oxidation of protein oxidation occurs. The degradation of intracellular oxidized proteins is intensively studied, but knowledge about the fate of oxidatively modified extracellular proteins is still limited. We studied
Autor:
Antje Wengner, Peter Ellinghaus, Arne Scholz, Kerstin Berhoerster, Andrea Haegebarth, Michael Haerter, Susanne Greschat, Holger Hess-Stumpp
Publikováno v:
Cancer Research. 71:4503-4503
Hypoxia is a hallmark of solid tumors and is associated with local invasion, metastatic spread and resistance to radio- as well as chemotherapy (Vaupel et al., 2004). Furthermore, hypoxia constitutes an independent negative prognostic factor in a div