Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Antje Krahn"'
Autor:
Rajan Somasundaram, Michael Höpfner, Detlef Schuppan, Bernhard Heine, Kerstin Maaser, Harald Stein, Martin Zeitz, Antje Krahn, Gesine Bradacs, Hans Scherübl, Kirsten Vormbrock, Patricia Grabowski, Andreas P. Sutter
Publikováno v:
Journal of Hepatology. 41:799-807
Background/Aims Hepatocellular carcinoma (HCC) is one of the most common causes of cancer deaths worldwide. Thus, novel therapies are urgently needed. A promising approach is the use of peripheral benzodiazepine receptor (PBR) ligands which inhibit t
Autor:
Patricia Grabowski, Andreas P. Sutter, Antje Krahn, Hans Scherübl, Michael Höpfner, Kerstin Maaser
Publikováno v:
Biochemical and Biophysical Research Communications. 324:878-886
Specific ligands of the peripheral benzodiazepine receptor (PBR) have been shown to induce both apoptosis and G1/G0 cell cycle arrest in colorectal cancers. The signaling pathways leading to cell cycle arrest are still unknown. Using cDNA array techn
Autor:
Michael Boshart, Regine Heilbronn, Stefan Weger, Antje Krahn, Christian Schetter, Markus Engstler
Publikováno v:
Nucleic Acids Research. 31:6206-6213
The subnuclear distribution of replication complex proteins is being recognized as an important factor for the control of DNA replication. Herpes simplex virus (HSV) single-strand (ss)DNA-binding protein, ICP8 (infected cell protein 8) accumulates in
Autor:
Antje Krahn, Kerstin Maaser, Harald Stein, Bernhard Heine, Martin Zeitz, Patricia Grabowski, Hans Scherübl, Yelda Oezdem, Heinz J. Buhr
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(5)
The peripheral benzodiazepine receptor (PBR) is overexpressed in a variety of cancers. In Unio Internationale Contra Cancrum (UICC) III colorectal cancers, a high level of PBR overexpression correlates with poor prognosis. However, little is known ab
Publikováno v:
Biochemical pharmacology. 67(9)
Specific ligands of the peripheral benzodiazepine receptor (PBR) activate pro-apoptotic and anti-proliferative signaling pathways. Previously, we found that PBR ligands activated the p38 mitogen-activated protein kinase (MAPK) pathway in esophageal c
Autor:
Ulrich Lass, Antje Krahn, Claus Jahrmarkt, Astrid Speer, Apard von Moers, Karl-Anton Kreuzer, Christian Schmidt, Stefanie Endesfelder
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 78(10)
Abnormalities in proliferation and differentiation of the dystrophin-deficient muscle are a controversial aspect of the pathogenesis of Duchenne muscular dystrophy (DMD). Analyses of molecules involved in cell cycle modulation do not exist in this co