Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Antje Fuchs"'
Publikováno v:
Reproductive Toxicology. 114:57-65
Lenalidomide is an immunomodulatory drug and is very effective in the management of a number of malignancies, including multiple myeloma. Like thalidomide, lenalidomide interacts with the cereblon E3 ligase complex, which results in targeted destruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e95702b0fa4bcfe4694077902a5468
https://doi.org/10.1016/j.reprotox.2022.10.005
https://doi.org/10.1016/j.reprotox.2022.10.005
Autor:
Sarah N. Campion, Christopher J. Bowman, Antje Fuchs, David Karanian, Payal Rana, Gregg D. Cappon
Publikováno v:
Birth defects researchREFERENCES.
Achondroplasia is an autosomal disorder caused by point mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) and resulting in gain of function. Recifercept is a potential disease modifying treatment for achondroplasia and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3261062f97b1f60d4f7ae6a010cfedae
https://pubmed.ncbi.nlm.nih.gov/36367445
https://pubmed.ncbi.nlm.nih.gov/36367445
Publikováno v:
Primate Biology. 7:1-4
Enhanced pre- and postnatal development (ePPND) studies have become the default developmental toxicity test for biopharmaceuticals if nonhuman primates represent the relevant species. Spontaneous pregnancy losses and infant deaths can be significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f3bc653dfff01233ebf3ac9a85b62c4
https://doi.org/10.5194/pb-7-1-2020
https://doi.org/10.5194/pb-7-1-2020
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 95
The incidence of spontaneous pregnancy/infant losses is highly variable in long-tailed macaques (cynomolgus monkey), making it potentially difficult to ascertain test item-related effects in developmental toxicity studies. Therefore, pregnancy normog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f55b284772948d09885bd1c4217cf91
https://pubmed.ncbi.nlm.nih.gov/32413491
https://pubmed.ncbi.nlm.nih.gov/32413491
Autor:
Kana Ishihara-Hattori, Ryuichi Katagiri, Werner Frings, Jun Amano, Shuichi Chiba, Antje Fuchs
Publikováno v:
Birth Defects Research. 109:843-856
Background SA237 is a humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody in which the constant and variable regions have been engineered for a longer plasma half-life. According to literature, blocking of IL-6 related functions could h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e96bbb13660ad80038342ea25e0f0caf
https://doi.org/10.1002/bdr2.1036
https://doi.org/10.1002/bdr2.1036
Publikováno v:
Reproductive Toxicology. 88:34-35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36cce5396abd8a7366dd1907a564ae2e
https://doi.org/10.1016/j.reprotox.2019.07.065
https://doi.org/10.1016/j.reprotox.2019.07.065
Autor:
Kohei Shiota, Weihua Li, Christof Schaefer, Martina Rauch, Yojiro Ooshima, Roland Solecki, Rupert Kellner, Gilbert Schönfelder, Aldert H. Piersma, Ibrahim Chahoud, A. Gall, Verena Heinrich, Ruth Clark, Jochen Buschmann, Antje Fuchs, Susan L. Makris, Thomas B. Knudsen, Beate Ulbrich, Francisco José Roma Paumgartten, Xuncheng Ding, Michael Oelgeschläger, Haidong Kan
Publikováno v:
Reproductive Toxicology. 57:140-146
This article is a report of the 8th Berlin Workshop on Developmental Toxicity held in May 2014. The main aim of the workshop was the continuing harmonization of terminology and innovations for methodologies used in the assessment of embryo- and fetot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6eb5f5a7ab42f38ff3f38d0c0abaf4
https://doi.org/10.1016/j.reprotox.2015.06.046
https://doi.org/10.1016/j.reprotox.2015.06.046
Autor:
Ryuichi, Katagiri, Kana, Ishihara-Hattori, Werner, Frings, Jun, Amano, Antje, Fuchs, Shuichi, Chiba
Publikováno v:
Birth defects research. 109(11)
SA237 is a humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody in which the constant and variable regions have been engineered for a longer plasma half-life. According to literature, blocking of IL-6 related functions could have an infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::490f089e06b2d4cb2d8f59de944c4dce
https://pubmed.ncbi.nlm.nih.gov/28504465
https://pubmed.ncbi.nlm.nih.gov/28504465
Publikováno v:
Documenta Ophthalmologica. 128:191-200
When visual acuity (VA) is assessed with spatially repetitive stimuli (e.g., gratings) in amblyopes, VA can be markedly overestimated. We evaluated to what extent this also applies to VEP-based objective acuity assessment, which typically uses gratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b4386410ad7d767262adaf47387fc1
https://doi.org/10.1007/s10633-014-9432-3
https://doi.org/10.1007/s10633-014-9432-3
Autor:
Wolfgang Lingk, Ali S. Faqi, Kohei Shiota, Steffen Schneider, Elkiane Macedo Rama, Sabine Kudicke, Roland Solecki, Ralph Gerspach, Mariska Tegelenbosch, Stephane Barbellion, Susan L. Makris, Heinrich Bürgin, Francisco José Roma Paumgartten, Ulrich Hübel, Samia Khalil, Helen Håkansson, Eva Tamborini, Ruth Clark, David Wise, Jochen Buschmann, Thomas B. Knudsen, Laura Comotto, Brigitte Bergmann, Barbara Heinrich-Hirsch, Konstanze Grote, Beate Ulbrich, Thelma Helena Inazaki, Verena Heinrich, Thomas Hofmann, Simone Müller, E.A.J. van Duijnhoven, Ibrahim Chahoud, Rudolf Pfeil, Antje Fuchs
Publikováno v:
Reproductive Toxicology. 35:48-55
This article summarizes the 7th Workshop on the Terminology in Developmental Toxicology held in Berlin, May 4-6, 2011. The series of Berlin Workshops has been mainly concerned with the harmonization of terminology and classification of fetal anomalie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beb7d4d921761fcd2ed182778e048f0
https://doi.org/10.1016/j.reprotox.2012.06.006
https://doi.org/10.1016/j.reprotox.2012.06.006