Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Antje Brouwer"'
An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression.
Autor:
Marc Leushacke, Ralf Spörle, Christof Bernemann, Antje Brouwer-Lehmitz, Johannes Fritzmann, Mirko Theis, Frank Buchholz, Bernhard G Herrmann, Markus Morkel
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23381 (2011)
In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Here, we identified a set of 21 genes, including FGF9, as determinants of tumor cell mo
Externí odkaz:
https://doaj.org/article/61c4d04199884c3696add6a3c54a6b40
Publikováno v:
Mechanisms of Development. 120(2):241-252
Aristaless-related genes encode a structurally defined group of homeoproteins that share a C-terminal stretch of amino acids known as the OAR- or aristaless domain. Many aristaless-related genes have been linked to major developmental functions, but
Autor:
Derk ten Berge, Antje Brouwer, Fons J. Verbeek, Mark Reijnen, Jeroen Korving, Frits Meijlink, Estia J. van Raaij, William Gaffield
Publikováno v:
Development. 128:2929-2938
The aristaless -related homeobox genes Prx1 and Prx2 are required for correct skeletogenesis in many structures. Mice that lack both Prx1 and Prx2 functions display reduction or absence of skeletal elements in the skull, face, limbs and vertebral col
Autor:
Frits Meijlink, Antje Brouwer, Estia J. van Raaij, J. B. Antoine Maintz, Derk ten Berge, Willem Hage, Fons J. Verbeek
Publikováno v:
Cytometry. 45:13-18
Background Cell proliferation is often studied using the incorporation of bromodeoxyuridine (BrdU). Immunohistochemical staining is then used to detect BrdU in the nucleus. To circumvent the observer bias and labor-intensive nature of manually counti
Autor:
Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Liesbeth van Iperen, Antje Brouwer, Beerend P. Hierck
Publikováno v:
Developmental Dynamics. 207:39-103
Using immunohistochemical techniques as well as in situ hybridization we were able to elicit the expression pattern of the beta 4 integrin subunit in the murine heart during development. We show that beta 4 is not expressed in the heart before E13 an
Autor:
Beerend P. Hierck, Antje Brouwer, Liesbeth van Iperen, Robert E. Poelmann, Adriana C. Gittenberger-de Groot
Publikováno v:
Developmental Dynamics. 206:100-111
The development of the heart from a single heart tube to a four chambered organ with two separated unidirectional flows is a highly complex process. Events like looping, septation, tissue remodelling, and development of valves take place in a time pe
Autor:
Antje Brouwer, Adriana C. Gittenberger-de Groot, Bertil Leussink, Robert E. Poelmann, Mohamed El Khattabi, Frits Meijlink
Publikováno v:
Mechanisms of Development. 52(1):51-64
Prx1 and Prx2 (previously called MHox and S8, respectively) are the members of a small subfamily of vertebrate homeobox genes expressed during embryogenesis from gastrulation onwards. We directly compared the expression domains of the Prx genes in de
Autor:
Sophie I. Candille, Sanne Kuijper, Antje Brouwer, Annemiek Beverdam, Carla Kroon, Gregory S. Barsh, Frits Meijlink
Publikováno v:
Development (Cambridge, England). 132(7)
The diverse cellular contributions to the skeletal elements of the vertebrate shoulder and pelvic girdles during embryonic development complicate the study of their patterning. Research in avian embryos has recently clarified part of the embryologica
Publisher Summary Paired (Prd)-type homeobox genes make up one of the major classes of the homeobox superfamily. Within this Prd class, a number of diverse sub-classes can be distinguished based on sequence similarities, including the presence of add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f6e35683a8574232aa4bda6b126776
https://doi.org/10.1016/s1569-1799(03)13005-5
https://doi.org/10.1016/s1569-1799(03)13005-5
Publikováno v:
Development (Cambridge, England). 128(20)
A group of mouse aristaless-related genes has been implicated in functions in the development of the craniofacial skeleton. We have generated an Alx3 mutant allele in which the lacZ coding sequence is inserted in-frame in the Alx3 gene and the sequen