Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Antje Blank"'
Dose‐dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin
Autor:
Nicolas Hohmann, Anna S. Friedrichs, Jürgen Burhenne, Antje Blank, Gerd Mikus, Walter E. Haefeli
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract The dose dependence of the effect of enzyme inducers and the effect of the combined administration of two inducers that exert their effect via the same induction pathway (pregnane X receptor) have not been well studied. Using oral midazolam
Externí odkaz:
https://doaj.org/article/c52b7ca26c1344ab99e4623076718f5b
Autor:
Micha Rosenkranz, Kristin Fürle, Julia Hibbert, Anne Ulmer, Arin Ali, Thomas Giese, Antje Blank, Walter E. Haefeli, Ernst Böhnlein, Michael Lanzer, Richard Thomson-Luque
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Radical control of malaria likely requires a vaccine that targets both the asymptomatic liver stages and the disease-causing blood stages of the human malaria parasite Plasmodium falciparum. While substantial progress has been made towards l
Externí odkaz:
https://doaj.org/article/8a2370c07fb045ea9013c090061948cc
Autor:
Antje Blank, Nicolas Hohmann, Marlen Dettmer, Anette Manka‐Stuhlik, Gerd Mikus, Felicitas Stoll, Marlies Stützle‐Schnetz, Daniel Thomas, Evelyn Exner, Beate Schmitt‐Bormann, Torsten Schaller, Rico Laage, Oliver Schönborn‐Kellenberger, Michaela Arndt, Walter E. Haefeli, Jürgen Krauss
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 10, Pp 2366-2377 (2022)
Abstract HDIT101 is a first‐in‐class humanized monoclonal antibody recognizing a conserved epitope in glycoprotein B, a target present on the surface of herpes simplex virus 1 (HSV‐1) and HSV‐2 particles as well as on virus‐infected cells.
Externí odkaz:
https://doaj.org/article/76662fa3327b4df79ec9dca274ca9822
Autor:
Vanessa Zhu, Jürgen Burhenne, Johanna Weiss, Mathias Haag, Ute Hofmann, Matthias Schwab, Stephan Urban, Gerd Mikus, David Czock, Walter E. Haefeli, Antje Blank
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Bulevirtide is a first-in-class antiviral drug to treat chronic hepatitis B/D. We investigated the drug-drug interaction potential and pharmacokinetics of high-dose subcutaneous bulevirtide (5 mg twice daily) with organic anion transpor
Externí odkaz:
https://doaj.org/article/9dadd7a5884e42199ebe15eb6e6fa246
Autor:
Louise Benning, Christian Morath, Tessa Kühn, Marie Bartenschlager, Heeyoung Kim, Jörg Beimler, Mirabel Buylaert, Christian Nusshag, Florian Kälble, Marvin Reineke, Maximilian Töllner, Matthias Schaier, Katrin Klein, Antje Blank, Paul Schnitzler, Martin Zeier, Caner Süsal, Ralf Bartenschlager, Thuong Hien Tran, Claudius Speer
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Seroconversion rates after COVID-19 vaccination are significantly lower in kidney transplant recipients compared to healthy cohorts. Adaptive immunization strategies are needed to protect these patients from COVID-19. In this prospective observationa
Externí odkaz:
https://doaj.org/article/2bedda14e53d490b9ba13a28b946f3f5
Autor:
Nicolas Hohmann, Farastuk Bozorgmehr, Petros Christopoulos, Gerd Mikus, Antje Blank, Jürgen Burhenne, Michael Thomas, Walter E. Haefeli
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 487-491 (2021)
The inhibitor of anaplastic lymphoma kinase (ALK) crizotinib significantly increases survival in patients with ALK‐positive non‐small cell lung cancer (NSCLC). When evaluating crizotinib pharmacokinetics (PKs) in patients taking the standard flat
Externí odkaz:
https://doaj.org/article/c3263b190a004989afea2f5553ef2b93
Autor:
Margaux Fresnais, Rémi Longuespée, Max Sauter, Torsten Schaller, Michaela Arndt, Jürgen Krauss, Antje Blank, Walter E. Haefeli, Jürgen Burhenne
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24329-24339 (2020)
Externí odkaz:
https://doaj.org/article/e7c9c27da8eb4f9089f3fc091dd9fb20
Autor:
Happiness Pius Saronga, Els Duysburgh, Siriel Massawe, Maxwell Ayindenaba Dalaba, Peter Wangwe, Felix Sukums, Melkizedeck Leshabari, Antje Blank, Rainer Sauerborn, Svetla Loukanova
Publikováno v:
BMC Health Services Research, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background QUALMAT project aimed at improving quality of maternal and newborn care in selected health care facilities in three African countries. An electronic clinical decision support system was implemented to support providers comply with
Externí odkaz:
https://doaj.org/article/db7429f330bf4346b981abf867d9d6ae
Autor:
Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Kathrin I. Foerster, Simon Hermann, Katja Häußler, Amin Muhareb, Simone Hummler, Johanna Weiss, Jürgen Burhenne, Walter E. Haefeli
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-2 (2020)
Abstract Objectives Primary objective: Evaluation of the effect of the proton pump inhibitor (PPI) pantoprazole on the absorption of hydroxychloroquine (HCQ). Secondary objectives: • Evaluation of the relationship between HCQ concentrations in whol
Externí odkaz:
https://doaj.org/article/b49e7901ebe64f9c9e6d04fd9fc7090b
Autor:
Nathan Mensah, Felix Sukums, Timothy Awine, Andreas Meid, John Williams, Patricia Akweongo, Jens Kaltschmidt, Walter E. Haefeli, Antje Blank
Publikováno v:
Global Health Action, Vol 8, Iss 0, Pp 1-10 (2015)
Background: The implementation of new technology can interrupt established workflows in health care settings. The Quality of Maternal Care (QUALMAT) project has introduced an (eCDSS) for antenatal care (ANC) and delivery in rural primary health care
Externí odkaz:
https://doaj.org/article/5dce150041de415990a39bce1175eab3