Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Antje Banning"'
Autor:
Ada-Sophia Clees, Verena Stolp, Björn Häupl, Dominik C. Fuhrmann, Frank Wempe, Marcel Seibert, Sarah Weber, Antje Banning, Ritva Tikkanen, Richard Williams, Bernhard Brüne, Hubert Serve, Frank Schnütgen, Ivana von Metzler, Nina Kurrle
Publikováno v:
Cells, Vol 11, Iss 2, p 292 (2022)
Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low oxygen levels (1–6% O2), known as hy
Externí odkaz:
https://doaj.org/article/deddf1251dd84b8d8b830f691dc2792f
Autor:
Antje Banning, Ritva Tikkanen
Publikováno v:
Cells, Vol 10, Iss 11, p 2813 (2021)
Splicing defects caused by mutations in the consensus sequences at the borders of introns and exons are common in human diseases. Such defects frequently result in a complete loss of function of the protein in question. Therapy approaches based on an
Externí odkaz:
https://doaj.org/article/d4e96def2f9f48ecb36882831720c586
Publikováno v:
Cells, Vol 10, Iss 5, p 1259 (2021)
Recombinant adeno-associated viruses (AAV) have emerged as an important tool for gene therapy for human diseases. A prerequisite for clinical approval is an in vitro potency assay that can measure the transduction efficiency of each virus lot produce
Externí odkaz:
https://doaj.org/article/bec499d86e1941a0a9d3a19f91cb3aae
Autor:
Miroslava Didiasova, Antje Banning, Heiko Brennenstuhl, Sabine Jung-Klawitter, Claudio Cinquemani, Thomas Opladen, Ritva Tikkanen
Publikováno v:
Cells, Vol 9, Iss 2, p 477 (2020)
Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is a genetic disorder that results from the aberrant metabolism of the neurotransmitter γ-amino butyric acid (GABA). The disease is caused by impaired activity of the mitochondrial enzyme succ
Externí odkaz:
https://doaj.org/article/2fe4b8fc534446b4beecf75e55f07846
Publikováno v:
Cells, Vol 3, Iss 1, Pp 129-149 (2014)
Flotillins are highly conserved proteins that localize into specific cholesterol rich microdomains in cellular membranes. They have been shown to be associated with, for example, various signaling pathways, cell adhesion, membrane trafficking and axo
Externí odkaz:
https://doaj.org/article/69ffc880ec2a4d21b5d9b9d8077ab3c2
Publikováno v:
Cells, Vol 7, Iss 4, p 28 (2018)
Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and flo
Externí odkaz:
https://doaj.org/article/2d32bf303579446cbb566bc05b521495
Publikováno v:
Cells, Vol 5, Iss 4, p 45 (2016)
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated sequence 9 (CRISPR/Cas9) system is widely used for genome editing purposes as it facilitates an efficient knockout of a specific gene in, e.g. cultured cells. Targeted
Externí odkaz:
https://doaj.org/article/3512e20841d54adcabfb03d24320923c
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84393 (2013)
Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting fu
Externí odkaz:
https://doaj.org/article/fb63a06146ca4b549cf7cfe54edf938b
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45514 (2012)
Flotillin-1 and flotillin-2 are important regulators of signal transduction pathways such as growth factor signaling. Flotillin expression is increased under pathological conditions such as neurodegenerative disorders and cancer. Despite their import
Externí odkaz:
https://doaj.org/article/902b77c578bf46c99c79ed047c25e0b3
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5722
Novel treatment strategies are emerging for rare, genetic diseases, resulting in clinical trials that require adequate biomarkers for the assessment of the treatment effect. For enzyme defects, biomarkers that can be assessed from patient serum, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43354cd3d0b2481b9449f70ea62ff89a
https://doi.org/10.3390/ijms24065722
https://doi.org/10.3390/ijms24065722