Výsledky vyhledávání - "Antje, Roetger"

Akademický článek

The Expression and Action of Decay-Accelerating Factor (CD55) in Human Malignancies and Cancer Therapy

Autor: Jan-Henrik Mikesch, Kathrin Schier, Antje Roetger, Ronald Simon, Horst Buerger, Burkhard Brandt

Publikováno v: Cellular Oncology, Vol 28, Iss 5-6, Pp 223-232 (2006)

Decay-accelerating factor (DAF, CD55) is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. Here DAF seems to exert different functions beyond its immunological role such as e.g. promo

Externí odkaz: https://doaj.org/article/056f3be651234baa885c576f3214ab2f

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The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy

Autor: Ronald Simon, Burkhard Brandt, Horst Buerger, Kathrin Schier, Jan-Henrik Mikesch, Antje Roetger

Publikováno v: Cellular Oncology : the Official Journal of the International Society for Cellular Oncology
Scopus-Elsevier
Cellular Oncology, Vol 28, Iss 5-6, Pp 223-232 (2006)
Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595c35dbb9eab46935ba86f81f6aa5c2
https://pubmed.ncbi.nlm.nih.gov/17167176

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Double- and Competitive-Differential PCR for Gene Dosage Quantitation

Autor: Alf Beckmann, Antje Roetger, Burkhard Brandt, Frank Gebhardt

An association of a loss of DNA replication control and the activation of erbB oncogenes can be deduced from studies with different cancers (1-5). In the first study on ovarian cancer 26% of the tumors had c-erbB-2 amplifications (6). The correlation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::090c9d009cb29e0b5b067231f369c6d6
https://doi.org/10.1385/1-59259-071-3:347

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Early placenta insulin-like growth factor (pro-EPIL) is overexpressed and secreted by c-erbB-2-positive cells with high invasion potential

Autor: Burkhard, Brandt, Antje, Roetger, Jean-Michel, Bidart, Jens, Packeisen, Katrin, Schier, Jan-Hendrik, Mikesch, Dirk, Kemming, Werner, Boecker, Dihua, Yu, Horst, Buerger

Publikováno v: Cancer research. 62(4)

By differential-display PCR a subclone of the SKBR3 cell line with high in vitro transendothelial invasiveness was identified to express increased levels of the INSL-4 gene. This new member of the insulin-like growth factor family encodes for a pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6754a09d2beec86d0fc984fb631bbe76
https://pubmed.ncbi.nlm.nih.gov/11861376

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c-erbB-2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells

Autor: Kurt S. Zaenker, Gerd Nikolai, Matthes Seeling, Jerzy-Roch Nofer, Gerd Assmann, Ralf Junker, Anja Merschjann, Gunda Dehmer-Möller, Thomas Dittmar, Burkhard Brandt, Antje Roetger

Publikováno v: Scopus-Elsevier

Separate mechanisms for oncogenesis and metastasis have been postulated. We show here that prolonged and invasive cell migration, a key mechanism in cancer metastasis, is linked to c-erbB-2 signaling. Cell lines with c-erbB-2 and EGFR expression and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6d7c46c588e4d3375a0b19800c317c
https://pubmed.ncbi.nlm.nih.gov/10544177

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Isolation of blood-borne epithelium-derived c-erbB-2 oncoprotein-positive clustered cells from the peripheral blood of breast cancer patients

Autor: Antje Roetger, Gerd Assmann, Stefan Heidl, Burkhard Brandt, Kurt S. Zänker, Christian Jackisch, Ralf J. Lelle

Publikováno v: International journal of cancer. 76(6)

Clinical studies including thousands of breast cancer patients have shown that c-erbB-2 is amplified and overexpressed in 20–30% of invasive human breast cancers and that it is associated with distant metastasis in specified patient subgroups. To i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74b3858c56c00c846783771473f2ca3
https://pubmed.ncbi.nlm.nih.gov/9626348

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Competitive-differential polymerase chain reaction for gene dosage estimation of erbB-1 (egfr), erbB-2, and erbB-3 oncogenes

Autor: Burkhard Brandt, Antje Roetger, Angelika Barnekow

Publikováno v: DNA and cell biology. 16(4)

Increases in the average gene copy number (AGCN) of the erbB oncogenes, especially the erbB-2 gene, have been found in a variety of human cancers. Such information is useful with respect to prognosis of the disease. Poor reproducibility and DNA damag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f909fc05a6038d5d006e8386a354c86
https://pubmed.ncbi.nlm.nih.gov/9150431

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