Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antje, Pommereau"'
Autor:
Antje Pommereau, Francesca Sassone, Alessandro Poli, Marcella De Silvestris, Lia Scarabottolo, Yasmin Zuschlag, Thomas Licher, Felix Bärenz
Publikováno v:
SLAS Discovery, Vol 29, Iss 8, Pp 100193- (2024)
GLUT9/SLC2A9 is a urate transporter and takes a fundamental role in the maintenance of normal serum urate levels. GLUT9 is the sole transporter of reabsorbed urate from renal epithelial cells to blood, thus making it an ideal pharmacological target f
Externí odkaz:
https://doaj.org/article/f162151e35ae468983f878500b759ea0
Autor:
Daniela Digles, Alvaro Ingles-Prieto, Vojtech Dvorak, Tamara A. M. Mocking, Ulrich Goldmann, Andrea Garofoli, Evert J. Homan, Alberto Di Silvio, Lucia Azzollini, Francesca Sassone, Mario Fogazza, Felix Bärenz, Antje Pommereau, Yasmin Zuschlag, Jasper F. Ooms, Jeppe Tranberg-Jensen, Jesper S. Hansen, Josefina Stanka, Hubert J. Sijben, Helena Batoulis, Eckhard Bender, Riccardo Martini, Adriaan P. IJzerman, David B. Sauer, Laura H. Heitman, Vania Manolova, Juergen Reinhardt, Alexander Ehrmann, Philipp Leippe, Gerhard F. Ecker, Kilian V. M. Huber, Thomas Licher, Lia Scarabottolo, Tabea Wiedmer, Giulio Superti-Furga
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
With over 450 genes, solute carriers (SLCs) constitute the largest transporter superfamily responsible for the uptake and efflux of nutrients, metabolites, and xenobiotics in human cells. SLCs are associated with a wide variety of human diseases, inc
Externí odkaz:
https://doaj.org/article/d3ca8f18dbc2476ea3722a966b570ca6
Autor:
Elisabeth Speckmeier, Antje Pommereau, Kay-Christoph Grosser, Hartmut Mors, Thomas C. Maier, Thomas Licher, Felix Bärenz
Publikováno v:
SLAS Discovery, Vol 27, Iss 5, Pp 298-305 (2022)
Acoustic droplet ejection mass spectrometry (ADE-MS) has recently emerged as a promising label-free, MS-based readout method for high throughput screening (HTS) campaigns in early pharmaceutical drug discovery, since it enables high-speed analysis di
Externí odkaz:
https://doaj.org/article/3d7dc617e5834613884663dd47a709a9
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03918c78c4de9247cb14bc21ece320fe
https://doi.org/10.1002/cpz1.755
https://doi.org/10.1002/cpz1.755
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5026c16fc6c9190d85a6aa9937917718
https://doi.org/10.1002/cpz1.650
https://doi.org/10.1002/cpz1.650
Autor:
Patrick Shum, Thomas Licher, John L. Kane, Carolin Gerbeth-Kreul, Gerhard Hessler, Antje Pommereau, Sven Ruf, Christian Engel, Linli Wei, Joerg Czech, Theresa A Kuntzweiler
Publikováno v:
SLAS Discovery. 26:783-797
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e4fb083c4e35d492c537df0250e79a
https://doi.org/10.1177/24725552211011180
https://doi.org/10.1177/24725552211011180
Autor:
Carolin, Gerbeth-Kreul, Antje, Pommereau, Sven, Ruf, John L, Kane, Theresa, Kuntzweiler, Gerhard, Hessler, Christian K, Engel, Patrick, Shum, LinLi, Wei, Joerg, Czech, Thomas, Licher
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(6)
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9160baf68ccf7faf0016023ba5f4dc1
https://pubmed.ncbi.nlm.nih.gov/33955247
https://pubmed.ncbi.nlm.nih.gov/33955247
Publikováno v:
SLAS Discovery. 9:409-416
In this study, the authors have compared the performance of 2 high-throughput screening assays for a serin/threonine kinase: a microplate-based, bioluminescent assay that uses the luciferin/luciferase system to monitor ATP consumption, and a microflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b5ef2ea6d38635444a2c6a12784f9a
https://doi.org/10.1177/1087057104264175
https://doi.org/10.1177/1087057104264175
Publikováno v:
Journal of Biomolecular Screening; Aug2004, Vol. 9 Issue 5, p409-416, 8p
Publikováno v:
Current Protocols; Apr2023, Vol. 3 Issue 4, p1-1, 1p