Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Antje, Lebrecht"'
Autor:
Ina Shehaj, Slavomir Krajnak, Katrin Almstedt, Yaman Degirmenci, Sophia Herzog, Antje Lebrecht, Valerie Catherine Linz, Roxana Schwab, Kathrin Stewen, Walburgis Brenner, Annette Hasenburg, Marcus Schmidt, Anne-Sophie Heimes
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1361 (2024)
Breast cancer (BC) poses a challenge in establishing new treatment strategies and identifying new prognostic and predictive markers due to the extensive genetic heterogeneity of BC. Very few studies have investigated the impact of mRNA expression of
Externí odkaz:
https://doaj.org/article/436bd216dafe4472bd66a3ed096dbda2
Autor:
Anne-Sophie Heimes, Katrin Almstedt, Slavomir Krajnak, Anne Runkel, Annika Droste, Roxana Schwab, Kathrin Stewen, Antje Lebrecht, Marco J. Battista, Walburgis Brenner, Annette Hasenburg, Mathias Gehrmann, Jan G. Hengstler, Marcus Schmidt
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2656 (2022)
Background: Monoclonal antibodies against PD-1 or PD-L1 have been established in clinical practice for the treatment of both early and advanced/metastatic triple-negative breast cancer. Beyond the established immune checkpoints (ICPs) (PD-1 and CTLA-
Externí odkaz:
https://doaj.org/article/34dbf5ecf98d4a23af271fabb54d11b1
Autor:
Marcus Schmidt, Veronika Weyer-Elberich, Jan G. Hengstler, Anne-Sophie Heimes, Katrin Almstedt, Aslihan Gerhold-Ay, Antje Lebrecht, Marco J. Battista, Annette Hasenburg, Ugur Sahin, Konstantine T. Kalogeras, Pirkko-Liisa Kellokumpu-Lehtinen, George Fountzilas, Ralph M. Wirtz, Heikki Joensuu
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background The clinical importance of tumor-infiltrating cluster of differentiation 4 (CD4) T cells is incompletely understood in early breast cancer. We investigated the clinical significance of CD4, forkhead box P3 (FOXP3), and B cell attr
Externí odkaz:
https://doaj.org/article/da0cf538b47445d3a9ca8a1909d519c0
Autor:
Jan G. Hengstler, Jörg Rahnenführer, Patrick Micke, Mathias Gehrmann, Heinz Koelbl, Ugur Sahin, Hans-Anton Lehr, Hans Bojar, Ralf Kronenwett, Martin Sebastian, Christina Cotarelo, Aslihan Gerhold-Ay, Volkmar Müller, Thomas Karn, Johan Botling, Anders Isaksson, Mats Lambe, Anders Berglund, Achim Rody, Hanna Göransson Kultima, Karolina Edlund, Lars Holmberg, Christine Solbach, Joanna D. Stewart, Rosemarie Marchan, Cristina Cadenas, Antje Lebrecht, Ilka Petry, Susanne Gebhard, Daniel Boehm, Zonglin Chen, Miriam Lohr, Amnah Othman, Seddik Hammad, Birte Hellwig, Marcus Schmidt
PDF file - 76K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f051a32af805aa209a9c56643365f9
https://doi.org/10.1158/1078-0432.22443738
https://doi.org/10.1158/1078-0432.22443738
Autor:
Jan G. Hengstler, Jörg Rahnenführer, Patrick Micke, Mathias Gehrmann, Heinz Koelbl, Ugur Sahin, Hans-Anton Lehr, Hans Bojar, Ralf Kronenwett, Martin Sebastian, Christina Cotarelo, Aslihan Gerhold-Ay, Volkmar Müller, Thomas Karn, Johan Botling, Anders Isaksson, Mats Lambe, Anders Berglund, Achim Rody, Hanna Göransson Kultima, Karolina Edlund, Lars Holmberg, Christine Solbach, Joanna D. Stewart, Rosemarie Marchan, Cristina Cadenas, Antje Lebrecht, Ilka Petry, Susanne Gebhard, Daniel Boehm, Zonglin Chen, Miriam Lohr, Amnah Othman, Seddik Hammad, Birte Hellwig, Marcus Schmidt
PDF file - 79K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b204b0392c0bda0d36ff90b7f73acaf
https://doi.org/10.1158/1078-0432.22443735
https://doi.org/10.1158/1078-0432.22443735
Autor:
Jan G. Hengstler, Marcus Schmidt, Jörg Rahnenführer, Agapios Sachinidis, Sibylle Loibl, Karsten E. Weber, Berno Tanner, Mathias Gehrmann, Christine Solbach, Heinz Koelbl, Annette Hasenburg, Walburgis Brenner, Rosemarie Marchan, Cristina Cadenas, Susanne Gebhard, Kathrin Stewen, Martina Seehase, Marco Battista, Daniel Boehm, Hans-Christian Kolberg, Manfred Hofmann, Gerald Hoffmann, Henryk Pilch, Bahriye Aktas, Antje Lebrecht, Katrin Madjar, Karolina Edlund
Genes with a significantly lower expression in patients predicted to not achieve a pCR with an extremely low predicted probability of pCR (a) and enes with a significantly higher expression in patients predicted to not achieve a pCR with an extremely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4b833c729694cddb6dbc921273bf8c
https://doi.org/10.1158/1078-0432.22483448
https://doi.org/10.1158/1078-0432.22483448
Autor:
Jan G. Hengstler, Marcus Schmidt, Jörg Rahnenführer, Agapios Sachinidis, Sibylle Loibl, Karsten E. Weber, Berno Tanner, Mathias Gehrmann, Christine Solbach, Heinz Koelbl, Annette Hasenburg, Walburgis Brenner, Rosemarie Marchan, Cristina Cadenas, Susanne Gebhard, Kathrin Stewen, Martina Seehase, Marco Battista, Daniel Boehm, Hans-Christian Kolberg, Manfred Hofmann, Gerald Hoffmann, Henryk Pilch, Bahriye Aktas, Antje Lebrecht, Katrin Madjar, Karolina Edlund
Purpose:Expression-based classifiers to predict pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) are not routinely used in the clinic. We aimed to build and validate a classifier for pCR after NACT.Patients and Methods:We perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b21909c9a063c83e0d5556165ec0ce
https://doi.org/10.1158/1078-0432.c.6531146
https://doi.org/10.1158/1078-0432.c.6531146
Autor:
Jan G. Hengstler, Marcus Schmidt, Jörg Rahnenführer, Agapios Sachinidis, Sibylle Loibl, Karsten E. Weber, Berno Tanner, Mathias Gehrmann, Christine Solbach, Heinz Koelbl, Annette Hasenburg, Walburgis Brenner, Rosemarie Marchan, Cristina Cadenas, Susanne Gebhard, Kathrin Stewen, Martina Seehase, Marco Battista, Daniel Boehm, Hans-Christian Kolberg, Manfred Hofmann, Gerald Hoffmann, Henryk Pilch, Bahriye Aktas, Antje Lebrecht, Katrin Madjar, Karolina Edlund
Published classifiers for prediction of pCR (a), study centers that contributed to the EXPRESSION trial (b), baseline characteristics of patients in the EXPRESSION trial (c), publicly available breast cancer datasets (d), comparison of patients who a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d43e9231b9b68c10de3abe61a9488eb
https://doi.org/10.1158/1078-0432.22483442
https://doi.org/10.1158/1078-0432.22483442
Autor:
Martin Schuler, Jan G. Hengstler, Heinz Koelbl, Hans-Anton Lehr, Mathias Gehrmann, Henryk Pilch, Susanne Gebhard, Ilka Schiffer-Petry, Wolfgang Weikel, Wulf Siggelkow, Antje Lebrecht, Eric Steiner, Cristina Cotarelo, Daniel Boehm, Mitra Schaeffer, Dirk Hasenclever, Marcus Schmidt
Supplementary Data from Prognostic Effect of Epithelial Cell Adhesion Molecule Overexpression in Untreated Node-Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51e40440ee69b12fc56d52da07d6442
https://doi.org/10.1158/1078-0432.22439754
https://doi.org/10.1158/1078-0432.22439754
Autor:
Jan G. Hengstler, Jörg Rahnenführer, Patrick Micke, Mathias Gehrmann, Heinz Koelbl, Ugur Sahin, Hans-Anton Lehr, Hans Bojar, Ralf Kronenwett, Martin Sebastian, Christina Cotarelo, Aslihan Gerhold-Ay, Volkmar Müller, Thomas Karn, Johan Botling, Anders Isaksson, Mats Lambe, Anders Berglund, Achim Rody, Hanna Göransson Kultima, Karolina Edlund, Lars Holmberg, Christine Solbach, Joanna D. Stewart, Rosemarie Marchan, Cristina Cadenas, Antje Lebrecht, Ilka Petry, Susanne Gebhard, Daniel Boehm, Zonglin Chen, Miriam Lohr, Amnah Othman, Seddik Hammad, Birte Hellwig, Marcus Schmidt
CCR Translation for This Article from A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45451058ad2be9525703af13d5467241
https://doi.org/10.1158/1078-0432.22443744.v1
https://doi.org/10.1158/1078-0432.22443744.v1