Zobrazeno 1 - 10
of 494
pro vyhledávání: '"Antiviral antibody"'
Autor:
Wangyang Li, Georgios D. Kitsios, William Bain, Chenxiao Wang, Tiao Li, Kristen V. Fanning, Rushikesh Deshpande, Xuebin Qin, Alison Morris, Janet S. Lee, Chunbin Zou
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has become a severe global public health crisis. Therefore, understanding the molecular details of SARS-C
Externí odkaz:
https://doaj.org/article/50250bd5b0e74c42b9c0fc21767e10ba
Autor:
Takahiro Hayakawa, Yoshio Nakano, Kana Hayakawa, Hiroaki Yoshimatu, Yoshikazu Hori, Kazuki Yamanishi, Hirofumi Yamanishi, Takayuki Ota, Tokuzo Fujimoto
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-4 (2019)
Abstract Background Fulminant type 1 diabetes is characterized by an intrinsic insulin deficiency resulting from the severe destruction of pancreatic β cells and it rapidly leads to ketoacidosis. However, the association between fulminant type 1 dia
Externí odkaz:
https://doaj.org/article/4132d8f155a84bb2a3e134fa2b65e046
Autor:
Dhuha H Nawab
Publikováno v:
Hum Vaccin Immunother
The coronavirus disease 2019 (COVID-19) pandemic highlights the urgent clinical need for efficient virus therapies and vaccines. Although the functional importance of antibodies is indisputable in viral infections, there are still significant unmet n
Autor:
Dirk Bauer, Mira Alt, Miriam Dirks, Anna Buch, Christiane S. Heilingloh, Ulf Dittmer, Bernd Giebel, André Görgens, Vivien Palapys, Maren Kasper, Anna M. Eis-Hübinger, Beate Sodeik, Arnd Heiligenhaus, Michael Roggendorf, Adalbert Krawczyk
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Herpes simplex virus (HSV) is a leading cause of blindness and viral encephalitis in the developed world. Upon reactivation from sensory neurons, HSV returns via axonal transport to peripheral tissues where it causes, e.g., severe, potentially blindi
Externí odkaz:
https://doaj.org/article/d3f76c485d3847d0b24e42eb30dad98f
Autor:
Xinghuan Wang, Shuang Guo, Jin Li, Gui Yang, Yirong Li, Yunbao Pan, Yueting Tang, Dongai Yao, Zhenshun Cheng, Xiaoyue Hong, Junli Fan, Yufeng Yuan, Xinran Li
Publikováno v:
Clinical Microbiology and Infection
Objectives The outbreak of the 2019 coronavirus disease (COVID-19) pandemic in Wuhan, China, has subsided after being hard hit by the disease and subsequent city lockdown. Information on the number of people involved in Wuhan is still inadequate. Thi
Autor:
Benjamin J. Doranz, Thomas Broge, Larissa B. Thackray, Lorellin A. Durnell, Cinque Soto, Peter Abbink, Edgar Davidson, Jacob Archer, Qing Tan, Steven G. Reed, Jenny Liang, Robert H. Carnahan, Joseph P. Nkolola, Caitlyn Linde, Elise Larson, Stacey Ertel, Jasmine Fuerte-Stone, Todd J. Suscovich, Michael S. Diamond, Robin G. Bombardi, Jesse H. Erasmus, Thomas C. Linnekin, Galit Alter, Rachel S. Nargi, Neal Van Hoeven, Vicky Roy, Matthew J. Gorman, James E. Crowe, Brian Granger, Pavlo Gilchuk, Mallorie E. Fouch, Taylor Jones, Amit P. Khandhar, Dan H. Barouch
Publikováno v:
Nature biomedical engineering
The emergence and re-emergence of highly virulent viral pathogens with the potential to cause a pandemic creates an urgent need for the accelerated discovery of antiviral therapeutics. Antiviral human monoclonal antibodies (mAbs) are promising candid
Autor:
Ariel S. Wirchnianski, Anna Z. Wec, Tony W. Ng, Steven A. Porcelli, Kartik Chandran, Hua-Xin Liao, J. Maximilian Fels, Christopher T. Johndrow, Kevin O. Saunders, John Chan, William R. Jacobs
Publikováno v:
The Journal of Immunology. 205:425-437
The continuing emergence of viral pathogens and their rapid spread into heavily populated areas around the world underscore the urgency for development of highly effective vaccines to generate protective antiviral Ab responses. Many established and n
Autor:
Stephen J. Elledge, Jane C. Burns, Mary Beth F. Son, Daniel Quiat, Zachary Pitkowsky, John T. Kanegaye, Chisato Shimizu, Adriana H. Tremoulet, Jane W. Newburger, Tomasz Kula
Publikováno v:
J Infect Dis
Clinical features of Kawasaki disease (KD) display overlap with common pediatric viral illnesses, leading some to hypothesize that a viral infection is the inciting event for KD. To investigate viral infection history in KD patients, we performed com
Autor:
David J. Sullivan, Andrew Pekosz, Andrew R. Crowley, Olivia Ajayi, Shmuel Shoham, Shiwei Xu, Ssavannah E. Butler, Andrew D. Redd, Arturo Casadevall, Ruchee Shrestha, Thomas C. Quinn, Margaret E. Ackerman, Kirsten Littlefield, Evan M. Bloch, Peter F. Wright, Harini Natarajan, Sarah E. Benner, Joshua A. Weiner, Ruth I. Connor, Wendy F. Weiland-Alter, Aaron A.R. Tobian
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Background While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. Methods We employ machine learning to
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