Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Antisense Orientation"'
Autor:
Nan Wu, Albert Yee, Ling Fang, Jian Ma, Burton B. Yang, Kaixuan Zeng, William W. Du, Juanjuan Lyu
Publikováno v:
Mol Ther
Circular RNAs (circRNAs) represent a large group of non-coding RNAs that are widely detected in mammalian cells. Although most circRNAs are generated in a sense orientation, there is a group of circRNAs that are synthesized in an antisense orientatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d02a5d14304cc6c596bbf833c6aeae3
https://doi.org/10.1016/j.ymthe.2021.08.002
https://doi.org/10.1016/j.ymthe.2021.08.002
Publikováno v:
Molecular Biology. 54:633-638
Long nonconding RNAs (lncRNAs) perform a variety of functions: they are involved in chromatin organization, regulation of gene expression at the transcriptional and post-transcriptional levels, and regulation of activity and stability of some protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d779108b121da1afdccab71445eb1633
https://doi.org/10.1134/s0026893320050106
https://doi.org/10.1134/s0026893320050106
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Evidence of the involvement of long noncoding RNAs (lncRNAs) in the pathogenesis of chronic obstructive pulmonary disease (COPD) is growing but still largely unknown. This study aims to explore the expression, functions and molecular mechanisms of Fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16ad40ec1ae88b985e398b7bb6da2f2
http://europepmc.org/articles/PMC8456124
http://europepmc.org/articles/PMC8456124
Autor:
Stefania Fedele, Francesca Persichetti, Raffaella Calligaris, Claudio Santoro, Piero Carninci, Yoshihide Hayashizaki, Silvia Zucchelli, Peter Heutink, Stefano Gustincich, Hideya Kawaji, Alistair R. R. Forrest, Timo Lassmann, Masayoshi Itoh, Patrizia Rizzu, Paolo Vatta
Publikováno v:
Molecular Neurobiology
Molecular neurobiology 56(8), 5392-5415 (2019). doi:10.1007/s12035-018-1465-2
Molecular Neurobiology, 56(8), 5392-5415. Humana Press
Zucchelli, S, Fedele, S, Vatta, P, Calligaris, R, Heutink, P, Rizzu, P, Itoh, M, Persichetti, F, Santoro, C, Kawaji, H, Lassmann, T, Hayashizaki, Y, Carninci, P, Forrest, A R R, Gustincich, S & FANTOM Consortium 2019, ' Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases ', Molecular Neurobiology, vol. 56, no. 8, pp. 5392-5415 . https://doi.org/10.1007/s12035-018-1465-2
Molecular neurobiology 56(8), 5392-5415 (2019). doi:10.1007/s12035-018-1465-2
Molecular Neurobiology, 56(8), 5392-5415. Humana Press
Zucchelli, S, Fedele, S, Vatta, P, Calligaris, R, Heutink, P, Rizzu, P, Itoh, M, Persichetti, F, Santoro, C, Kawaji, H, Lassmann, T, Hayashizaki, Y, Carninci, P, Forrest, A R R, Gustincich, S & FANTOM Consortium 2019, ' Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases ', Molecular Neurobiology, vol. 56, no. 8, pp. 5392-5415 . https://doi.org/10.1007/s12035-018-1465-2
Natural antisense transcripts are common features of mammalian genes providing additional regulatory layers of gene expression. A comprehensive description of antisense transcription in loci associated to familial neurodegenerative diseases may ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120ea6efe086086ac3137d6fc47f8071
http://europepmc.org/articles/PMC6614138
http://europepmc.org/articles/PMC6614138
Autor:
David J. Gallagher, Vikas Rai, Michael P. Farrell, Yirong Li, Magan Trottier, Erin E. Salo-Mullen, Liying Zhang, Heleen M. van der Klift, Zsofia K. Stadler, Ciyu Yang
Germline mutations in the DNA mismatch repair (MMR) genes cause Lynch syndrome (LS). Insertions of retrotransposons in MMR genes have been reported as a rare cause of LS. Here, we present a novel SINE-VNTR-Alu (SVA) insertion in exon 12 of MSH2 in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d29f3503f918e1486ee203c7639f133
https://doi.org/10.22541/au.160619405.59308303/v1
https://doi.org/10.22541/au.160619405.59308303/v1
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
BMC Genomics
BMC Genomics
Background In contrast to unidirectional promoters wherein antisense transcription results in short transcripts which are rapidly degraded, bidirectional promoters produce mature transcripts in both sense and antisense orientation. To understand the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942f299319d9c6e509fa67afd6dd40cc
http://link.springer.com/article/10.1186/s12864-018-4697-7
http://link.springer.com/article/10.1186/s12864-018-4697-7
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Frontiers in Plant Science
Frontiers in Plant Science, Vol 11 (2020)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
Universitat Autònoma de Barcelona
Frontiers in Plant Science
Frontiers in Plant Science, Vol 11 (2020)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
LTR-retrotransposons share a common genomic organization in which the 5′ long terminal repeat (LTR) is followed by the gag and pol genes and terminates with the 3′ LTR. Although GAG-POL-encoded proteins are considered sufficient to accomplish the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf8863b04a97051f7626a0837ac657e
https://pubmed.ncbi.nlm.nih.gov/32528484
https://pubmed.ncbi.nlm.nih.gov/32528484
Autor:
Michael J. Davis, Zhentu Ying
Publikováno v:
Plant disease. 88(4)
Papaya (Carica papaya) was transformed via Agrobacterium-mediated transformation with four constructs containing either the unmodified or modified coat protein (CP) gene of Florida isolate H1K of Papaya ringspot virus (PRSV). The CP genes were in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52590efd21e06a0db9c1bbae7df53370
https://pubmed.ncbi.nlm.nih.gov/30812613
https://pubmed.ncbi.nlm.nih.gov/30812613
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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1863:194647
In plants, posttranscriptional gene silencing (PTGS) is induced by small RNAs (sRNAs) generated from various dsRNA precursors. To assess the impact of dsRNA origin, we compared downregulation of GFP expression triggered by inverted repeat (IR), antis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425023448fa30320786ec383cc5099fc
https://doi.org/10.1016/j.bbagrm.2020.194647
https://doi.org/10.1016/j.bbagrm.2020.194647