Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Antis G. George"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Sudden unexpected death in epilepsy (SUDEP) is the leading epilepsy-related cause of premature mortality in people with intractable epilepsy, who are 27 times more likely to die than the general population. Impairment of the central control
Externí odkaz:
https://doaj.org/article/83a6b645b38c407fa366f4a129208f31
Autor:
Renaud C. Gom, Dhyey Bhatt, Bianca R. Villa, Antis G. George, Alexander W. Lohman, Richelle Mychasiuk, Jong M. Rho, G. Campbell Teskey
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105335- (2021)
Objectives: A prolonged vasoconstriction/hypoperfusion/hypoxic event follows self-terminating focal seizures. The ketogenic diet (KD) has demonstrated efficacy as a metabolic treatment for intractable epilepsy and other disorders but its effect on lo
Externí odkaz:
https://doaj.org/article/160750426e64448285582cddf18a1ed6
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Seizures can result in a severe hypoperfusion/hypoxic attack that causes postictal memory and behavioral impairments. However, neither postictal changes to microvasculature nor Ca2+ changes in key cell types controlling blood perfusion have been visu
Externí odkaz:
https://doaj.org/article/1887ad402b024477bcbfdef289570e19
Autor:
Antis G. George, Jordan S. Farrell, Roberto Colangeli, Alexandra K. Wall, Renaud C. Gom, Mitchell T. Kesler, Cristiane Rodriguez de la Hoz, Bianca R. Villa, Tefani Perera, Jong M. Rho, Deborah Kurrasch, G. Campbell Teskey
Publikováno v:
Neuropharmacology. 231:109513
Autor:
Sydney A. Harris, Antis G. George, Karlene T. Barrett, Morris H. Scantlebury, G. Campbell Teskey
Publikováno v:
EpilepsiaREFERENCES. 63(10)
In adult brain tissue, oxygen levels typically remain in the normoxic zone, but status epilepticus results in hyperoxia, whereas brief self-terminating seizures lead to postictal hypoxia. The dynamic changes in oxygen levels and the underlying mechan
Autor:
Antis G. George, Jordan S. Farrell, Roberto Colangeli, Alexandra K. Wall, Renaud C. Gom, Mitchell T. Kesler, Cristiane L de la Hoz, Tefani Perera, Jong M. Rho, Deborah Kurrasch, G. Campbell Teskey
Epilepsy is at times a fatal disease. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of mortality in people with intractable epilepsy and is defined by exclusion; non-accidental, non-toxicologic, and non-anatomic causes of death. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8167e32e0647f715c4ffd36f4aad5c3c
https://doi.org/10.1101/2022.03.25.485818
https://doi.org/10.1101/2022.03.25.485818
Autor:
Richelle Mychasiuk, Jong M. Rho, G. Campbell Teskey, Bianca R. Villa, Antis G. George, Alexander W. Lohman, Renaud C. Gom, Dhyey Bhatt
Publikováno v:
Neurobiology of Disease, Vol 154, Iss, Pp 105335-(2021)
Objectives A prolonged vasoconstriction/hypoperfusion/hypoxic event follows self-terminating focal seizures. The ketogenic diet (KD) has demonstrated efficacy as a metabolic treatment for intractable epilepsy and other disorders but its effect on loc
Autor:
Jordan S. Farrell, Roberto Colangeli, Antis G. George, Sachin Patel, Yulong Li, Keith A. Sharkey, Kaikai He, Ao Dong, Philip J. Kingsley, Maria Morena, Ivan Soltesz, Lawrence J. Marnett, G. Campbell Teskey, Marshal D. Wolff, Toni A. Patrick, Barna Dudok, Matthew N. Hill, Kwaku Addo-Osafo
Publikováno v:
Neuron
Summary The brain’s endocannabinoid system is a powerful controller of neurotransmitter release, shaping synaptic communication under physiological and pathological conditions. However, our understanding of endocannabinoid signaling in vivo is limi
Autor:
Thomas J. Phillips, Marshal D. Wolff, Alexandra K. Wall, Paolo Federico, Antis G. George, Roberto Colangeli, G. Campbell Teskey, Jordan S. Farrell
Publikováno v:
Epilepsia. 58:1493-1501
Summary A recent article by Farrell et al. characterizes the phenomenon, mechanisms, and treatment of a local and severe hypoperfusion/hypoxia event that occurs in brain regions following a focal seizure. Given the well-established role of cerebral i
Previously we showed that seizures result in a severe hypoperfusion/hypoxic attack that results in postictal memory and behavioral impairments (Farrell et al., 2016). However, neither postictal changes in microvasculature nor Ca2+ changes in key cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8eba093e7955108043cdae7d92d1b6
https://doi.org/10.1101/644039
https://doi.org/10.1101/644039