Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Antiprotozoal Agents/chemistry"'
Autor:
F. Matthew Kuhlmann, Nicolas Fasel, Jahangheer S. Shaik, Suzanne M. Hickerson, Stephen M. Beverley, Haroun Zangger, Lon-Fye Lye, Erin A. Brettmann, Katherine Owens, Natalia S. Akopyants, Catherine Ronet, Dayna M. Oschwald
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 43, pp. 11998-12005
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 43, pp. 11998-12005
Many Leishmania (Viannia) parasites harbor the double-stranded RNA virus Leishmania RNA virus 1 (LRV1), which has been associated with increased disease severity in animal models and humans and with drug treatment failures in humans. Remarkably, LRV1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38901f3493f223efa5bc8b27ca72304
http://www.pnas.org/content/113/43/11998.long
http://www.pnas.org/content/113/43/11998.long
Autor:
Sanja Glisic, Filipa V. Sena, Andrej Perdih, Milan Sencanski, Ana M. Tomás, Strahinja Stevanovic, Filipe M. Sousa, Manuela M. Pereira, Margarida Duarte, Tom Solmajer
Publikováno v:
Molecules, Vol 23, Iss 4, p 772 (2018)
Molecules
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecules; Volume 23; Issue 4; Pages: 772
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecules; Volume 23; Issue 4; Pages: 772
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
There is an urgent need for the discovery of new antileishmanial drugs with a new mechanism of action. Type 2 NADH dehydrogenase from Leishmania infantum (LiNDH2) is an enzyme of the parasite’s respiratory system, which catalyzes the electron trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb72e7114e9a50d21f2e155a7cd3c73d
https://doi.org/10.3390/molecules23040772
https://doi.org/10.3390/molecules23040772
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
To characterize the production and application of carbohydrate functionalized poly(d,l-lactide-co-glycolide) (PLGA) nanospheres as immune-modulatory mediators in the treatment of visceral leishmaniasis (VL). Materials & methods: PLGA nanospheres were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c92d4d2fd5a3fef1b6e366a1323355
https://repositorio-aberto.up.pt/handle/10216/118191
https://repositorio-aberto.up.pt/handle/10216/118191
Autor:
Daniela Barros, Ricardo Jorge Dinis-Oliveira, Maria Teresa Baltazar, Anabela Cordeiro-da-Silva, Sofia A. Costa Lima, Joana Cunha, Ricardo Silvestre
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This work aims to develop poly(d,l-lactide-co-glycolide) (PLGA)-nanospheres containing amphotericin B (AmB) with suitable physicochemical properties and anti-parasitic activity for visceral leishmaniasis (VL) therapy. When compared with unloaded-PLGA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab938897999474dfed9a7da2525e1998
https://pubmed.ncbi.nlm.nih.gov/24412471
https://pubmed.ncbi.nlm.nih.gov/24412471