Zobrazeno 1 - 10
of 3 751
pro vyhledávání: '"Antiplasmodial"'
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background The most widely used anti-malarial drug artemisinin (ART) is metabolized extensively, but the therapeutic capacity of its major metabolite remains unknown. Whether the major metabolite of ART (ART-M) contributes to its antiplasmod
Externí odkaz:
https://doaj.org/article/7c42943e75f8407594a7f225885404ce
Autor:
Sujeet Singh, Hemant Arya, Welka Sahu, K. Sony Reddy, Surendra Nimesh, Bader Saud Alotaibi, Mohammed Ageeli Hakami, Hassan H. Almasoudi, Khater Balatone Gezira Hessien, Mohammad Raghibul Hasan, Summya Rashid, Tarun Kumar Bhatt
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 238-249 (2024)
AbstractMalaria is a mosquito-borne infectious disease that is caused by the Plasmodium parasite. Most of the available medication are losing their efficacy. Therefore, it is crucial to create fresh leads to combat malaria. Green silver nanoparticles
Externí odkaz:
https://doaj.org/article/d7fd68e73f2b446caf8b0989d856cd51
Autor:
David Chinemerem Nwobodo, Nkeoma Nkasi Okoye, Mahasin Sifir Mudkhur, Joseph Chinedu Ikem, Peter Maduabuchi Eze, Festus Basden Chiedu Okoye, Morteza Saki, Charles Okechukwu Esimone
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Ethnomedicinal plants are thought to have better prospects of harboring endophytes that produce natural products with pharmacological activities. This study aimed to investigate the antiplasmodial and anticancer properties of secondary metab
Externí odkaz:
https://doaj.org/article/3142d9c6e45b486194cbc86d5f0cb255
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 10, Iss 3, Pp 213-223 (2024)
Background & Aims: Malaria disease imposes a substantial global health burden, urging the search for effective treatments amid escalating drug resistance. This study investigates the antiplasmodial potential of Azanza garckeana root bark extract in P
Externí odkaz:
https://doaj.org/article/c2efafdd83ed40e0ba25ba109908395c
Autor:
Atthaphon Konyanee, Prapaporn Chaniad, Arnon Chukaew, Apirak Payaka, Abdi Wira Septama, Arisara Phuwajaroanpong, Walaiporn Plirat, Chuchard Punsawad
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Malaria is a major global health concern, particularly in tropical and subtropical countries. With growing resistance to first-line treatment with artemisinin, there is an urgent need to discover novel antimalarial drugs. Mesua fe
Externí odkaz:
https://doaj.org/article/03bf435cacb24790aaa8b62839af3885
Publikováno v:
Asia Pacific Journal of Medical Toxicology, Vol 13, Iss 2, Pp 49-55 (2024)
Background: In the midst of transient conquests by medications against malaria, Plasmodium parasites are the foremost public health problem globally. The emergence of drug-resistant parasites has worsened the condition, emphasizing the need for effec
Externí odkaz:
https://doaj.org/article/a877fbdfee9f4644bd74c5fcd3375119
Publikováno v:
Green Processing and Synthesis, Vol 13, Iss 1, Pp 154-62 (2024)
Externí odkaz:
https://doaj.org/article/869717d02e084207a3943f4a8560852d
Publikováno v:
Trends in Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-14 (2024)
Malaria is a prevalent infectious disease that is transmitted by parasites through the bite of infected mosquitoes. Despite advancements in medical science, malaria is still a significant global health challenge, especially in regions like northern N
Externí odkaz:
https://doaj.org/article/d8d9b914de414ee5861190db53846424
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundDespite the widely reported potentials of n-Hexadecanoic acid (HA) as a bioactive, its multi-stage antiplasmodial activity and toxicity profiles remain largely unknown.MethodologyThus, this study uses a combination of in silico approaches a
Externí odkaz:
https://doaj.org/article/7a925e2a40024ce28b73a5ea4d108dbc
Autor:
Isaac Damilare Asiyanbola, Michael Oluwatoyin Daniyan, Tivere Susan Opoggen, Ifedolapo Olabisi Olayemi, Olufunso Bayo Adeoye, Victor Olukayode Ekundina, Idris Ajayi Oyemitan
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 3, Pp 100581- (2024)
Background: One of the three principles that govern the pathogenesis of cerebral malaria (CM) is the activation of immunological and systemic inflammatory responses. Available reports have revealed the anti-inflammatory and antioxidant activity of th
Externí odkaz:
https://doaj.org/article/cb1b147e59e746e6806e08309cbc2487