Presence of benznidazole conjugated metabolites in urine identified by β-glucuronidase treatment

Autor: Facundo García Bournissen, Jaime Altcheh, María Elena Marson, Guido Mastrantonio, Guillermo Moscatelli, Samantha Moroni

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e18034, Published: 16 MAR 2020
Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e18034
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e18034
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Paediatrics Publications
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)

Chagas disease is a serious public health problem in Latin America and, due to migration, in other nonendemic regions. Benznidazole (BNZ) is first choice drug in pediatric therapeutics. However, little is known regarding its metabolism in humans. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293b9447909ff6344dc4283106eab35a
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100520&lng=en&tlng=en

Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination

Autor: Chaccour, C.J. (Carlos J.), Kobylinsk, K.C. ( Kevin C.), Bassat, Q. (Quique), Bousema, T. (Teun), Drakeley, C. (Chris), Alonso, P. (Pedro), Foy, B.D. (Brian D.)

Publikováno v: Malaria Journal, 12, 153
Malaria Journal, 12, pp. 153
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

Contains fulltext : 118709.pdf (Publisher’s version ) (Open Access) BACKGROUND: The heterogeneity of malaria transmission makes widespread elimination a difficult goal to achieve. Most of the current vector control measures insufficiently target ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ba5eee87828f99e872a739c95fdae82f
http://hdl.handle.net/2066/118709