Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Antineoplastic Agents, Immunological/pharmacology"'
1
G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment
Autor: Martinez Sanz, Paula, van Rees, Dieke J, van Zogchel, Lieke M J, Klein, Bart, Bouti, Panagiota, Olsman, Hugo, Schornagel, Karin, Kok, Ivana, Sunak, Ali, Leeuwenburg, Kira, Timmerman, Ilse, Dierselhuis, Miranda P, Kholosy, Waleed M, Molenaar, Jan J, van Bruggen, Robin, van den Berg, Timo K, Kuijpers, Taco W, Matlung, Hanke L, Tytgat, Godelieve A M, Franke, Katka, Afd Pharmaceutics, Pharmaceutics
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central
Journal for immunotherapy of cancer, 9(5):e002259. BioMed Central Ltd.
BackgroundCurrent immunotherapy for patients with high-risk neuroblastoma involves the therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority of neuroblastoma tumors. Opsonized tumor cells are killed through antibo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8c22e38a8b458ee9e9cfac080fa47
https://doi.org/10.1136/jitc-2020-002259
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2
Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints
Autor: Pedro Romero, Marion Bossennec, Isabelle Durand, Bertrand Dubois, Christelle Machon, David Bauché, Julien Faget, Nicolas Gourdin, Christophe Caux, Jérôme Guitton, Julien C. Marie, Camilla Jandus, Nicolas Chopin, Olivier Tredan, Christine Ménétrier-Caux, Céline Rodriguez, Selena Vigano
Publikováno v: Cancer Research, Vol. 78, No 13 (2018) pp. 3604-3618
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Cancer research, vol. 78, no. 13, pp. 3604-3618
Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
The production of CD73-derived adenosine (Ado) by Tregs has been proposed as a resistance mechanism to anti-PD-1 therapy in murine tumor models. We reported that human Tregs express the ectonucleotidase CD39, which generates AMP from ATP, but do not
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375fbfa2c51d166ee5ae1ba8adac560
https://doi.org/10.1158/0008-5472.can-17-2405
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3
Immune Effector Functions of Human IgG2 Antibodies against EGFR
Autor: Steffen Kahle, Francesca Montenegro, Frank J. Beurskens, Hanke L. Matlung, Thies Rösner, J. H. Marco Jansen, Thomas Valerius, Mitchell Evers, Jeanette H. W. Leusen, Timo K. van den Berg
Publikováno v: Molecular cancer therapeutics, 18(1), 75-88. American Association for Cancer Research Inc.
MOLECULAR CANCER THERAPEUTICS, 18(1), 75. American Association for Cancer Research Inc.
Molecular Cancer Therapeutics, 18(1), 75-88. American Association for Cancer Research Inc.
Rösner, T, Kahle, S, Montenegro, F, Matlung, H L, Jansen, J H M, Evers, M, Beurskens, F, Leusen, J H W, van den Berg, T K & Valerius, T 2019, ' Immune effector functions of human IgG2 antibodies against EGFR ', Molecular Cancer Therapeutics, vol. 18, no. 1, pp. 75-88 . https://doi.org/10.1158/1535-7163.MCT-18-0341
Three FDA-approved epidermal growth factor receptor (EGFR) antibodies (cetuximab, panitumumab, necitumumab) are clinically available to treat patients with different types of cancers. Interestingly, panitumumab is of human IgG2 isotype, which is ofte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692caaf503db12710c08d5729c4e4a0
https://pure.amc.nl/en/publications/immune-effector-functions-of-human-igg2-antibodies-against-egfr(b301d497-2553-4fca-aedd-daa513223dbd).html
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4
Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy
Autor: Bialkowski, Lukasz, Van Der Jeught, Kevin, Bevers, Sanne, Tjok Joe, Patrick, Renmans, Dries, Heirman, Carlo, Aerts, Joeri L, Thielemans, Kris
Improved understanding of cancer immunology has provided insight into the phenomenon of frequent tumor recurrence after initially successful immunotherapy. A delicate balance exists between the capacity of the immune system to control tumor growth an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3848::0bd02733dcb6ba1bffc6575823d6af05
https://hdl.handle.net/20.500.14017/fea8fbae-3684-443d-b0c5-eb3e2c5fae1c
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5
Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth
Autor: Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak-Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan-Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl-Henrik, Cao, Yihai, Griffioen, Arjan W
Publikováno v: Thijssen, V L J L, Paulis, Y W J, Nowak-Sliwinska, P, Deumelandt, K L, Hosaka, K, Soetekouw, P M M B, Cimpean, A M, Raica, M, Pauwels, P, van den Oord, J J, Tjan-Heijnen, V C G, Hendrix, M J, Heldin, C-H, Cao, Y & Griffioen, A W 2018, ' Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth ', Journal of Pathology, vol. 246, no. 4, pp. 447-458 . https://doi.org/10.1002/path.5152
Journal of Pathology, 246(4), 447-458. Wiley
The Journal of Pathology
Journal of Pathology, 246(4), 447-458. John Wiley and Sons Ltd
The Journal of Pathology, Vol. 246, No 4 (2018) pp. 447-458
The journal of pathology
Aggressive tumor cells can adopt an endothelial cell-like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis. This adoptive mechanism is referred to as vascular mimicry and it is associated with poor s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5435e58f79198e5e138f84ce9e9101ff
https://research.vumc.nl/en/publications/0a2bde55-0895-49ee-9b6a-f1d907174034
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6
Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma
Autor: Lisbet Hölmich Rosenkrantz, Marco Donia, Rikke Andersen, Jon Bjoern, Inge Marie Svane, Rikke Birgitte Lyngaa, Sine Reker Hadrup
Publikováno v: Bjoern, J, Lyngaa, R, Andersen, R, Rosenkrantz, L H, Hadrup, S R, Donia, M & Svane, I M 2017, ' Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma ', OncoTarget, vol. 8, no. 16, pp. 27062-27074 . https://doi.org/10.18632/oncotarget.16003
Bjørn, J, Lyngaa, R B, Andersen, R, Rosenkrantz, L H, Hadrup, S R, Donia, M & Svane, I M 2017, ' Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma ', OncoTarget, vol. 8, no. 16, pp. 27062-27074 . https://doi.org/10.18632/oncotarget.16003
Oncotarget
// Jon Bjoern 1, 2 , Rikke Lyngaa 3, 1 , Rikke Andersen 1, 2 , Lisbet Holmich Rosenkrantz 4 , Sine Reker Hadrup 3, 1 , Marco Donia 1, 2 , Inge Marie Svane 1, 2 1 Center for Cancer Immune Therapy, Herlev Hospital, University of Copenhagen, Copenhagen,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7471d7341b5e1be9ac8c2d2d2b691f5a
https://curis.ku.dk/portal/da/publications/influence-of-ipilimumab-on-expanded-tumour-derived-t-cells-from-patients-with-metastatic-melanoma(a922dd04-bba2-4ccc-adac-af06273d2557).html
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