Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Antineoplastic/toxicity"'
1
Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy
Autor: da Silva Ferreira, A R, van der Aa, S A J, Wehkamp, T, Wardill, H R, Ten Klooster, J P, Garssen, J, Harthoorn, L F, Hartog, A, Harmsen, H J M, Tissing, W J E, van Bergenhenegouwen, J, Afd Pharmacology, Pharmacology
Publikováno v: Scientific Reports, 11(1), 1. NLM (Medline)
Scientific Reports
Scientific Reports, 11:22911. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific reports
Background: Gastrointestinal mucositis remains a significant complication of anticancer treatment, with limited anti-mucositis interventions. Currently, there are few validated in vitro systems suitable to study the mechanisms of mucosal injury. Ther
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f0be1bb49864df41a96eba18f87645
https://dspace.library.uu.nl/handle/1874/419704
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2
Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes
Autor: Taina Palosaari, Jochem Louisse, Pilar Prieto, Francesca Pistollato, Rob C. I. Wüst, Susanne Bremer, Manuela Barilari, Peter Macko
Publikováno v: Toxicology in Vitro, 42, 182-190. Elsevier Limited
Louisse, J, Wüst, R C I, Pistollato, F, Palosaari, T, Barilari, M, Macko, P, Bremer, S & Prieto, P 2017, ' Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes ', Toxicology in Vitro, vol. 42, pp. 182-190 . https://doi.org/10.1016/j.tiv.2017.04.023
Toxicology in vitro, 42, 182-190. Elsevier Limited
The present study assesses acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs), with the aim to obtain in vitro biomarkers that can be used as readouts to predict in vivo cardiotoxicity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12badb039aa75c4161220a991025aafc
http://www.scopus.com/inward/record.url?scp=85018349514&partnerID=8YFLogxK
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3
Dissertation/ Thesis
Toxicidade e ação antitumoral de um derivado do quimioterápico etoposídeo (oleato de etoposídeo) associado a uma microemulsão rica em colesterol
Autor: Prete, Ana Cristina Lo
Ao utilizar uma microemulsão lipídica artificial rica em colesterol (LDE), como transportador de fármacos antineoplásicos, é possível aumentar a dose administrada com redução dos efeitos tóxicos. Quando injetada na circulação, a LDE liga-s
Externí odkaz: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-24022015-073248/
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4
Akademický článek
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5
Akademický článek
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6
Protective effect of carvedilol alone and coadministered with diltiazem and prednisolone on doxorubicin and 5-fluorouracil-induced hepatotoxicity and nephrotoxicity in rats
Autor: Gabriel O. Oludadepo, Kennedy I. Amagon, Abidemi J. Akindele, Daniel D. Osiagwu, Dhirendra Pratap Singh
Publikováno v: Pharmacology Research & Perspectives
This study investigated the protective effects of carvedilol alone and coadministered with prednisolone and diltiazem on doxorubicin (DOX) and 5‐fluorouracil (5‐FU)‐induced toxicity. Each of 2 pools of 70 female rats were randomly allotted into
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4370acd2624ae1c0fa90674e3b9cbb76
https://doi.org/10.1002/prp2.381
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7
Akademický článek
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9
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes
Autor: Ken Mackie, Mohanraj Rajesh, Yoshihiro Kashiwaya, Partha Mukhopadhyay, Sandor Batkai, Oleg V. Evgenov, Lucas Liaudet, Vivek Patel, György Haskó, Pal Pacher
Publikováno v: Cardiovascular Research, vol. 85, no. 4, pp. 773-784
Aims Here we investigated the mechanisms by which cardiovascular CB1 cannabinoid receptors may modulate the cardiac dysfunction, oxidative stress, and interrelated cell death pathways associated with acute/chronic cardiomyopathy induced by the widely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed29e81108260d4753bceae0486ffb6
https://pubmed.ncbi.nlm.nih.gov/19942623
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10
Dissertation/ Thesis
Toxicidade e ação antitumoral de um derivado do quimioterápico etoposídeo (oleato de etoposídeo) associado a uma microemulsão rica em colesterol
Autor: Ana Cristina Lo Prete
Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Ao utilizar uma microemulsão lipídica artificial rica em colesterol (LDE), como transportador de fármacos antineoplásicos, é possível aumentar a dose administrada com redução dos efeitos tóxicos. Quando injetada na circulação, a LDE liga-s
Externí odkaz: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-24022015-073248/
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