Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Antimo Gioiello"'
Autor:
Riccardo Ronchetti, Luigi Alfonso Pannone, Bruno Cerra, Emidio Camaioni, Gianfranco Lopopolo, Emanuele Attolino, Antimo Gioiello
Publikováno v:
Molecules, Vol 28, Iss 23, p 7859 (2023)
Mometasone furoate is a synthetic corticosteroid used in the treatment of skin inflammatory conditions, hay fever and asthma. The industrial manufacturing routes to mometasone furoate are generally accompanied by the formation of numerous process imp
Externí odkaz:
https://doaj.org/article/d976aa964adf42c7a81b6b6ca039c861
Autor:
Elisa Bianconi, Alessandra Riccio, Luana Ruta, Carlo Bigiotti, Andrea Carotti, Sonia Moretti, Bruno Cerra, Antimo Gioiello, Simone Ferlin, Efisio Puxeddu, Antonio Macchiarulo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5535 (2023)
PD-1/PD-L1 protein complex is attracting a great deal of interest as a drug target for the design of immune therapies able to block its assembly. Although some biologic drugs have entered clinical use, their poor response rate in patients are demandi
Externí odkaz:
https://doaj.org/article/390a90695a4140999d9d93d54335d7ae
Autor:
Desirée Bartolini, Anna Maria Stabile, Sabrina Bastianelli, Daniela Giustarini, Sara Pierucci, Chiara Busti, Carmine Vacca, Anna Gidari, Daniela Francisci, Roberto Castronari, Antonella Mencacci, Manlio Di Cristina, Riccardo Focaia, Samuele Sabbatini, Mario Rende, Antimo Gioiello, Gabriele Cruciani, Ranieri Rossi, Francesco Galli
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102041- (2021)
Viral infections sustain their replication cycle promoting a pro-oxidant environment in the host cell. In this context, specific alterations of the levels and homeostatic function of the tripeptide glutathione have been reported to play a causal role
Externí odkaz:
https://doaj.org/article/7277eccf2fff453cb26f76084edad457
Autor:
Francesco Galli, Giada Marcantonini, Daniela Giustarini, Maria Cristina Albertini, Anna Migni, Linda Zatini, Antimo Gioiello, Ranieri Rossi, Desirée Bartolini
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1366 (2022)
SARS-CoV-2 infection can cause a severe respiratory distress syndrome with inflammatory and thrombotic complications, the severity of which increases with patients’ age and presence of comorbidity. The reasons for an age-dependent increase in the r
Externí odkaz:
https://doaj.org/article/3cc4fdbaa5454e77bb642ae43deb1446
Autor:
Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Bruno Cerra, Antimo Gioiello, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1453-1459 (2018)
Bile acids have been shown to inhibit human (h) carbonic anhydrases (CA, EC 4.2.1.1) along the gastrointestinal tract, including hCA II. The elucidation of the hormonal inhibition mechanism of the bile acid cholate to hCA II was provided in 2014 by X
Externí odkaz:
https://doaj.org/article/c4da7939832b4fa48310ee9d70017d17
Autor:
Aldo Roda, Pierpaolo Greco, Patrizia Simoni, Valentina Marassi, Giada Moroni, Antimo Gioiello, Barbara Roda
Publikováno v:
Chemosensors, Vol 9, Iss 6, p 122 (2021)
A simple and versatile continuous air-segmented flow sensor using immobilized luciferase was designed as a general miniaturized platform based on sensitive biochemiluminescence detection. The device uses miniaturized microperistaltic pumps to deliver
Externí odkaz:
https://doaj.org/article/197a32280a444c18866acbd3131d9325
Autor:
Bruno Cerra, Antonio Macchiarulo, Andrea Carotti, Emidio Camaioni, Ina Varfaj, Roccaldo Sardella, Antimo Gioiello
Publikováno v:
Molecules, Vol 25, Iss 3, p 640 (2020)
In the present work, we illustrate the ability of high-performance liquid chromatography (HPLC) analysis to assist the synthesis of chiral imidazolines within our medicinal chemistry programs. In particular, a Chiralpak® IB® column containing cellu
Externí odkaz:
https://doaj.org/article/35ebf727cabf4c338062ba69c68d1d89
Autor:
Alessio Lodola, Silvia Rivara, Elisabetta Barocelli, Francesca De Franco, Paola Vicini, Antimo Gioiello, Carmine Giorgio, Iftiin Hassan-Mohamed, Riccardo Castelli, Daniele Pala, Matteo Incerti, Marco Mor, Massimiliano Tognolini, Simonetta Russo
Publikováno v:
Molecules, Vol 18, Iss 10, Pp 13043-13060 (2013)
The Eph–ephrin system plays a critical role in tumor growth and vascular functions during carcinogenesis. We had previously identified cholanic acid as a competitive and reversible EphA2 antagonist able to disrupt EphA2-ephrinA1 interaction and to
Externí odkaz:
https://doaj.org/article/f84fc8073c5b4103a212dfea3999704e
Autor:
Francesco Venturoni, Bruno Cerra, Maura Marinozzi, Emidio Camaioni, Antimo Gioiello, Roberto Pellicciari
Publikováno v:
Catalysts, Vol 8, Iss 12, p 600 (2018)
We report novel insights into the cascade rearrangement of destabilized vinyl cations deriving from the BF3·Et2O-induced decomposition of cyclic α-diazo-β-hydroxy ketones in turn prepared by aldol-type condensation of cycloalkanones with diazoacet
Externí odkaz:
https://doaj.org/article/68adca418a6d414886c9ff916466788c
Autor:
Antimo Gioiello, Antonio Macchiarulo, Roberto Pellicciari, Roberto Nuti, Roccaldo Sardella, Benedetto Natalini, Paola Sabbatini, Paolo Filipponi
Publikováno v:
Molecules, Vol 18, Iss 9, Pp 10497-10513 (2013)
Bile acids have emerged as versatile signalling compounds of a complex network of nuclear and membrane receptors regulating various endocrine and paracrine functions. The elucidation of the interconnection between the biological pathways under the bi
Externí odkaz:
https://doaj.org/article/8e4133ca8e6640ba9b50e69e84beee9c