Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Antimicrobial Cationic Peptide"'
Akademický článek
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Autor:
Kiss, Cedric, Gall, Flavio M, Dreier, Birgit, Adams, Michael, Riedl, Rainer, Plückthun, Andreas, Mittl, Peer R E
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:1439-1450
Peptides comprising many hydrophobic amino acids are almost insoluble under physiological buffer conditions, which complicates their structural analysis. To investigate the three-dimensional structure of the hydrophobic leucinostatin derivative ZHAWO
Autor:
Rosa Bellavita, Annarita Falanga, Francesco Merlino, Gabriella D’Auria, Nicola Molfetta, Anella Saviano, Francesco Maione, Umberto Galdiero, Maria Rosaria Catania, Stefania Galdiero, Paolo Grieco, Emanuela Roscetto, Lucia Falcigno, Elisabetta Buommino
The increasing resistance of fungi to conventional antifungal drugs has prompted worldwide the search for new compounds. In this work, we investigated the antifungal properties of acylated Temporin L derivatives, Pent-1B and Dec-1B, against Candida a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7476417299f885afa7e9e39437a02f19
Autor:
Bruno Casciaro, Salvatore Di Maro, Floriana Cappiello, Stefania Galdiero, Alfonso Carotenuto, Maria Luisa Mangoni, Diego Brancaccio, Francesco Merlino, Tom N. Grossmann, Ettore Novellino, Paolo Grieco, Rosa Bellavita, Annarita Falanga, Elisabetta Buommino
Publikováno v:
Journal of medicinal chemistry, 64(15), 11675-11694. American Chemical Society
Journal of Medicinal Chemistry
Bellavita, R, Casciaro, B, Di Maro, S, Brancaccio, D, Carotenuto, A, Falanga, A, Cappiello, F, Buommino, E, Galdiero, S, Novellino, E, Grossmann, T N, Mangoni, M L, Merlino, F & Grieco, P 2021, ' First-in-Class Cyclic Temporin L Analogue : Design, Synthesis, and Antimicrobial Assessment ', Journal of medicinal chemistry, vol. 64, no. 15, pp. 11675-11694 . https://doi.org/10.1021/acs.jmedchem.1c01033
Journal of Medicinal Chemistry
Bellavita, R, Casciaro, B, Di Maro, S, Brancaccio, D, Carotenuto, A, Falanga, A, Cappiello, F, Buommino, E, Galdiero, S, Novellino, E, Grossmann, T N, Mangoni, M L, Merlino, F & Grieco, P 2021, ' First-in-Class Cyclic Temporin L Analogue : Design, Synthesis, and Antimicrobial Assessment ', Journal of medicinal chemistry, vol. 64, no. 15, pp. 11675-11694 . https://doi.org/10.1021/acs.jmedchem.1c01033
The pharmacodynamic and pharmacokinetic properties of bioactive peptides can be modulated by introducing conformational constraints such as intramolecular macrocyclizations, which can involve either the backbone and/or side chains. Herein, we aimed a
Autor:
Carla Zannella, Annalisa Chianese, Luciana Palomba, Maria Elena Marcocci, Rosa Bellavita, Francesco Merlino, Paolo Grieco, Veronica Folliero, Anna De Filippis, Marialuisa Mangoni, Lucia Nencioni, Gianluigi Franci, Massimiliano Galdiero
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2060
The COVID-19 pandemic has evidenced the urgent need for the discovery of broad-spectrum antiviral therapies that could be deployed in the case of future emergence of novel viral threats, as well as to back up current therapeutic options in the case o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6a6c8be8485ce9e6eff4dd4708c54b
https://hdl.handle.net/11588/901833
https://hdl.handle.net/11588/901833
Autor:
Annalisa Chianese, Carla Zannella, Alessandra Monti, Anna De Filippis, Nunzianna Doti, Gianluigi Franci, Massimiliano Galdiero
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 883
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 883, p 883 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 883, p 883 (2022)
Viral infections represent a serious threat to the world population and are becoming more frequent. The search and identification of broad-spectrum antiviral molecules is necessary to ensure new therapeutic options, since there is a limited availabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc2e28fd2485c16629b07022b368939
http://hdl.handle.net/11386/4780243
http://hdl.handle.net/11386/4780243
Autor:
Diana Carolina Henao Arias, Juan Felipe Osorio-Méndez, Germán Alberto Téllez Ramirez, Maribel Rojas-Montoya, Lily Johanna Toro S, Juliana Franco Castrillón, Jhon Carlos Castaño Osorio
Publikováno v:
Journal of Insect Science
The Coleoptera Scarabaeidae family is one of the most diverse groups of insects on the planet, which live in complex microbiological environments. Their immune systems have evolved diverse families of Host Defense Peptides (HDP) with strong antimicro
Autor:
Maria Elena Marcocci, Bianka Gabriela Jackowska, Carla Prezioso, Virginia Protto, Marta De Angelis, Francesco Saverio Di Leva, Bruno Casciaro, Alfonso Carotenuto, Maria Luisa Mangoni, Anna Teresa Palamara, Valeria Pietropaolo, Giovanna De Chiara, Lucia Nencioni
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7194
Herpes simplex virus type-1 (HSV-1) and John Cunningham polyomavirus (JCPyV) are widely distributed DNA viruses causing mainly asymptomatic infection, but also mild to very severe diseases, especially when these viruses reach the brain. Some drugs ha
Autor:
Antimo Di Maro, Angela Arciello, Renata Piccoli, Valeria Cafaro, Eliana Dell’Olmo, C. Valeria L. Giosafatto, Rosa Gaglione, Sara Ragucci, Raffaele Porta
Background Microbial transglutaminase (mTG) has been successfully used to produce site-specific protein conjugates derivatized at the level of Gln and/or Lys residues for different biotechnological applications. Here, a recombinant peptide identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3b718530bf8599fc820c392c5b09a3
http://hdl.handle.net/11588/833435
http://hdl.handle.net/11588/833435
Akademický článek
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