Zobrazeno 1 - 10
of 20 626
pro vyhledávání: '"Antimalarial"'
Autor:
Bernard K. Turkson, Isaac K. Amponsah, Alfred Ofori Agyemang, Merlin L. K. Mensah, Reinhard I. Nketia, Desmond Nkrumah, Michael F. Baidoo, Abraham Y. Mensah, Emmanuel Achaab, Burnett Tetteh Accam
Publikováno v:
Clinical Phytoscience, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The use of herbal products for the treatment of malaria, has increased globally. However, inadequate scientific studies about the safety and effectiveness of such herbal products have been raised. Also, the reduced sensitivity of the malaria
Externí odkaz:
https://doaj.org/article/f0c44a8a1ae44f3a9811bbdbc733795d
Autor:
Swaraj Kumar Babu, Sameer Maharana, Satyaranjan Chhatria, Dibya Ranjan Sahoo, Ashirbad Nanda, Satish Kanhar, Prativa K. Behera, Sanjib Mohanty, Pradeep Kumar Naik, Praveen Kishore Sahu
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 8, Pp 350-358 (2024)
Objective: To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain (Pf3D7), its clinical isolate (Pf140/SS), and Plasmodium berghei ANKA (PbA). Methods: Using ring-stage survival assay, phenotypic assessments, and
Externí odkaz:
https://doaj.org/article/0a6f21f5bb4d4356b5362a2383390550
Autor:
Getu Habte, Sisay Habte, Oda Jilo, Wondwosen Alemu, Kedir Eyasu, Welela Meka, Getabalew Shifera, Wubishet Gezimu, Milkias Dugasa, Sanbato Tamiru, Meta Mamo, Abiyot Kelecha
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background Malaria continues to wreak havoc on the well-being of the community. Resistant parasites are jeopardizing the treatment. This is a wake-up call for better medications. Folk plants are the key starting point for antimalarial drug d
Externí odkaz:
https://doaj.org/article/e68bd77f10c841abb70fd33fa4f30033
Autor:
Awet Alem Teklemichael, Aiko Teshima, Asahi Hirata, Momoko Akimoto, Mayumi Taniguchi, Gholam Khodakaramian, Takashi Fujimura, Fuyuki Tokumasu, Kenji Arakawa, Shusaku Mizukami
Publikováno v:
Tropical Medicine and Health, Vol 52, Iss 1, Pp 1-11 (2024)
Abstract Background Natural products play a key role as potential sources of biologically active substances for the discovery of new drugs. This study aimed to identify secondary metabolites from actinomycete library extracts that are potent against
Externí odkaz:
https://doaj.org/article/d497c2553d3142a18b877ee7299c7af5
Autor:
Reagan M. Mogire, Silviane A. Miruka, Dennis W. Juma, Case W. McNamara, Ben Andagalu, Jeremy N. Burrows, Elodie Chenu, James Duffy, Bernhards R. Ogutu, Hoseah M. Akala
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Drug discovery is an intricate and costly process. Repurposing existing drugs and active compounds offers a viable pathway to develop new therapies for various diseases. By leveraging publicly available biomedical information, it is possible
Externí odkaz:
https://doaj.org/article/9abd7be432b44ac9ad401606323a2e80
Autor:
Ameyo Monique Dorkenoo, Marian Warsame, Essoham Ataba, Manani Hemou, Kossi Yakpa, Efoe Sossou, M’badi Mitigmsagou, Carmel Diwaba Teou, Emmanuelle Caspar, Laurence Ma, Koffi Edem Djadou, Tinah Atcha-Oubou, Charlotte Rasmussen, Didier Menard
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) are the currently recommended first- and second-line therapies for uncomplicated Plasmodium falciparum infections in Togo. This study assessed the efficacy of th
Externí odkaz:
https://doaj.org/article/84a2192568d44c24b6bbd91ca6b741bc
Publikováno v:
Cogent Public Health, Vol 11, Iss 1 (2024)
Malaria is an infectious disease caused protozoa in genus Plasmodium. In spite of the efforts made in the fight against malaria, this tropic infectious disease is still one of the most common vector borne disease in the WHO African region. Therefore,
Externí odkaz:
https://doaj.org/article/8bb8d5c8837b42f48cbd2ae172f3537e
Autor:
Pathy B. Lokole, Galilée G. Byamungu, Paulin K. Mutwale, Nadège K. Ngombe, Celestin N. Mudogo, Rui W. M. Krause, Christian I. Nkanga
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Malaria is one of the most devastating diseases across the globe, particularly in low-income countries in Sub-Saharan Africa. The increasing incidence of malaria morbidity is mainly due to the shortcomings of preventative measures such as the lack of
Externí odkaz:
https://doaj.org/article/41081c707d324e2da89d06d71c272418
Autor:
Ruotong Liu, Guoming Li, Mei Li, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Ruhe Liao, Qin Xu, Zhu-Chun Bei, Yabin Song
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Naphthoquine is a promising candidate for antimalarial combination therapy. Its combination with artemisinin has demonstrated excellent efficacy in clinical trials conducted across various malaria-endemic areas. A co-formulated combination o
Externí odkaz:
https://doaj.org/article/96a54aa90e314be9a031f5d890a34312
Autor:
Prapaporn Chaniad, Arnon Chukaew, Prasit Na-ek, Gorawit Yusakul, Litavadee Chuaboon, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Abdi Wira Septama, Chuchard Punsawad
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The potent antiplasmodial activity of 1-hydroxy-5,6,7-trimethoxyxanthone (HTX), isolated from Mammea siamensis T. Anders. flowers, has previously been demonstrated in vitro. However, its in vivo activity has not been reported. The
Externí odkaz:
https://doaj.org/article/fcb52c5479704bf5b1f038b1d11e54b5