Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Antigens/metabolism"'
Autor:
Habets, Denise H. J., Al-Nasiry, Salwan, Nagelkerke, Sietse Q., Voorter, Christina E. M., Spaanderman, Marc E. A., Kuijpers, Taco W., Wieten, Lotte
Publikováno v:
Scientific Reports, 13(1):5232. Nature Publishing Group
Scientific reports, 13(1). Nature Publishing Group
Habets, D H J, Al-Nasiry, S, Nagelkerke, S Q, Voorter, C E M, Spaanderman, M E A, Kuijpers, T W & Wieten, L 2023, ' Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with CD16a expression and anti-HLA antibody status ', Scientific Reports, vol. 13, no. 1, 5232, pp. 5232 . https://doi.org/10.1038/s41598-023-32156-9
Scientific reports, 13(1). Nature Publishing Group
Habets, D H J, Al-Nasiry, S, Nagelkerke, S Q, Voorter, C E M, Spaanderman, M E A, Kuijpers, T W & Wieten, L 2023, ' Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with CD16a expression and anti-HLA antibody status ', Scientific Reports, vol. 13, no. 1, 5232, pp. 5232 . https://doi.org/10.1038/s41598-023-32156-9
Natural Killer (NK) cells have been implicated in recurrent pregnancy loss (RPL). The p.Val176Phe (or Val158Phe) Single Nucleotide Polymorphism (SNP) in the FCGR3A gene encoding the FcγRIIIA or CD16a receptor has been associated with an enhanced aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e051c1e4fa81426c2fa47ed20383c0a1
https://research.vumc.nl/en/publications/9557a9ce-0dff-4d01-9101-707550d2f73d
https://research.vumc.nl/en/publications/9557a9ce-0dff-4d01-9101-707550d2f73d
Autor:
Ramón Pérez-Núñez, Alejandro Chamorro, María Fernanda González, Pamela Contreras, Rocío Artigas, Alejandro H. Corvalán, Brigitte van Zundert, Christopher Reyes, Pablo R. Moya, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Journal of neuroinflammation, vol. 20, no. 1, pp. 5
Background In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can also cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb301e5d6b950fe73cff422018afa9d9
https://serval.unil.ch/notice/serval:BIB_9764A8B87F3E
https://serval.unil.ch/notice/serval:BIB_9764A8B87F3E
Autor:
Teunissen, M, Ahrens, N S, Snel, L, Narcisi, R, Kamali, S A, van Osch, G J V M, Meij, B P, Mastbergen, S C, Sivasubramaniyan, K, Tryfonidou, M A, CS_Locomotion, Chirurgie, Interne geneeskunde GD
Publikováno v:
Stem cell research & therapy, 13(1), 1. BioMed Central
STEM CELL RESEARCH & THERAPY, 13(1):457. BioMed Central Ltd.
STEM CELL RESEARCH & THERAPY, 13(1):457. BioMed Central Ltd.
Background Synovial membrane-derived mesenchymal progenitor cells (SM-MPCs) are a promising candidate for the cell-based treatment of osteoarthritis (OA) considering their in vitro and in vivo capacity for cartilage repair. However, the OA environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23cdae20dfa0a67014d344c13b269c1
https://doi.org/10.1186/s13287-022-03144-z
https://doi.org/10.1186/s13287-022-03144-z
Autor:
Demmers, Laura C., Kretzschmar, Kai, Van Hoeck, Arne, Bar-Epraïm, Yotam E., van den Toorn, Henk W.P., Koomen, Mandy, van Son, Gijs, van Gorp, Joost, Pronk, Apollo, Smakman, Niels, Cuppen, Edwin, Clevers, Hans, Heck, Albert J.R., Wu, Wei, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Tumor heterogeneity is a major cause of therapeutic resistance. Immunotherapy may exploit alternative vulnerabilities of drug-resistant cells, where tumor-specific human leukocyte antigen (HLA) peptide ligands are promising leads to invoke targeted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b44dcfe7d35bd9a39853a8fe316ef9
http://link.springer.com/article/10.1038/s41467-020-19142-9
http://link.springer.com/article/10.1038/s41467-020-19142-9
Autor:
Susanne Dechantsreiter, Ashley R. Ambrose, Jonathan D. Worboys, Joey M. E. Lim, Sylvia Liu, Rajesh Shah, M. Angeles Montero, Anne Marie Quinn, Tracy Hussell, Gillian M. Tannahill, Daniel M. Davis
Publikováno v:
Dechantsreiter, S, Ambrose, A R, Worboys, J D, Lim, J M E, Liu, S, Shah, R, Montero, M A, Quinn, A M, Hussell, T, Tannahill, G M & Davis, D M 2022, ' Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super-resolution microscopy ', Journal of Extracellular Vesicles, vol. 11, no. 4, e12215, pp. e12215 . https://doi.org/10.1002/jev2.12215
The diverse origins, nanometre-scale and invasive isolation procedures associated with extracellular vesicles (EVs) mean they are usually studied in bulk and disconnected from their parental cell. Here, we used super-resolution microscopy to directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ab40764f7116d8772cf4621a748d5e
https://pubmed.ncbi.nlm.nih.gov/35415881
https://pubmed.ncbi.nlm.nih.gov/35415881
Publikováno v:
Clinical and Experimental Immunology
Clinical and Experimental Immunology, Wiley, 2020, 200 (1), pp.89-104. ⟨10.1111/cei.13412⟩
Clin Exp Immunol
Clinical and Experimental Immunology, Wiley, 2020, 200 (1), pp.89-104. ⟨10.1111/cei.13412⟩
Clin Exp Immunol
Summary Chronic antigen stimulation can lead to immune exhaustion (a state of T cell dysfunction). Several phenotypical signatures of T cell exhaustion have been described in various pathological situations, characterized by aberrant expression of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224fd1281567a921d5b700e491fdcbe5
https://doi.org/10.1111/cei.13412
https://doi.org/10.1111/cei.13412
Autor:
Victoria Bingham, Manuel Salto-Tellez, R Stephen McCain, Eamon McCarron, Helen G Coleman, Chintapuza Chisambo, Stephanie G Craig, Eileen Parkes, Damian T. McManus, Stephen McQuaid, Richard C. Turkington, Nathan B. Reid, Jacqueline A James
Publikováno v:
McCain, R S, McManus, D T, McQuaid, S, James, J A, Salto-Tellez, M, Reid, N B, Craig, S, Chisambo, C, Bingham, V, McCarron, E, Parkes, E, Turkington, R C & Coleman, H G 2020, ' Alcohol intake, tobacco smoking, and esophageal adenocarcinoma survival: a molecular pathology epidemiology cohort study ', Cancer Causes and Control, vol. 31, no. 1, pp. 1-11 . https://doi.org/10.1007/s10552-019-01247-2
Cancer Causes & Control
Cancer Causes & Control
Purpose To investigate the association between cigarette smoking, alcohol consumption, and esophageal adenocarcinoma survival, including stratified analysis by selected prognostic biomarkers. Methods A population-representative sample of 130 esophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9feb1d24c680e0031cb59ff9dc8ebf54
https://doi.org/10.1007/s10552-019-01247-2
https://doi.org/10.1007/s10552-019-01247-2
Autor:
Martinez Sanz, Paula, van Rees, Dieke J, van Zogchel, Lieke M J, Klein, Bart, Bouti, Panagiota, Olsman, Hugo, Schornagel, Karin, Kok, Ivana, Sunak, Ali, Leeuwenburg, Kira, Timmerman, Ilse, Dierselhuis, Miranda P, Kholosy, Waleed M, Molenaar, Jan J, van Bruggen, Robin, van den Berg, Timo K, Kuijpers, Taco W, Matlung, Hanke L, Tytgat, Godelieve A M, Franke, Katka, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central
Journal for immunotherapy of cancer, 9(5):e002259. BioMed Central Ltd.
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central
Journal for immunotherapy of cancer, 9(5):e002259. BioMed Central Ltd.
BackgroundCurrent immunotherapy for patients with high-risk neuroblastoma involves the therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority of neuroblastoma tumors. Opsonized tumor cells are killed through antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8c22e38a8b458ee9e9cfac080fa47
https://doi.org/10.1136/jitc-2020-002259
https://doi.org/10.1136/jitc-2020-002259
Autor:
Ignacio Santecchia, Ivo G. Boneca, Frédérique Vernel-Pauillac, Ben Adler, Delphine Bonhomme, Gerald L. Murray, Martine Caroff, Pierre Germon, Catherine Werts
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 12, p e1009173 (2020)
PLoS Pathogens, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 8, p e1008639 (2020)
PLoS Pathogens, Public Library of Science, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 12, p e1009173 (2020)
PLoS Pathogens, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 8, p e1008639 (2020)
Leptospirosis is a worldwide re-emerging zoonosis caused by pathogenic Leptospira spp. All vertebrate species can be infected; humans are sensitive hosts whereas other species, such as rodents, may become long-term renal carrier reservoirs. Upon infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13a49d5e8b035c7e56a6269ac9a0d7
https://hal.inrae.fr/hal-02949538
https://hal.inrae.fr/hal-02949538
Autor:
Chensu Wang, Mathilde Allard, Grégory Verdeil, Michael Hebeisen, Darrell J. Irvine, Martin F. Bachmann, Nathalie Rufer, Daniel E. Speiser, Connie B. Gilfillan, Mona O. Mohsen
Publikováno v:
European Journal of Immunology
European journal of immunology, vol. 50, no. 4, pp. 505-514
Gilfillan, Connie B; Wang, Chensu; Mohsen, Mona O.; Rufer, Nathalie; Hebeisen, Michael; Allard, Mathilde; Verdeil, Grégory; Irvine, Darrell J; Bachmann, Martin F.; Speiser, Daniel E (2020). Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density. European journal of immunology, 50(4), pp. 505-514. Wiley-VCH 10.1002/eji.201948355
European journal of immunology, vol. 50, no. 4, pp. 505-514
Gilfillan, Connie B; Wang, Chensu; Mohsen, Mona O.; Rufer, Nathalie; Hebeisen, Michael; Allard, Mathilde; Verdeil, Grégory; Irvine, Darrell J; Bachmann, Martin F.; Speiser, Daniel E (2020). Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density. European journal of immunology, 50(4), pp. 505-514. Wiley-VCH 10.1002/eji.201948355
It is known that for achieving high affinity antibody responses, vaccines must be optimized for antigen dose/density, and the prime/boost interval should be at least 4 weeks. Similar knowledge is lacking for generating high avidity T‐cell responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b57974412bb6fed5b2be5cee05873