Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Antigens, Protozoan/immunology"'
Autor:
Gemma Moncunill, Jason Carnes, William Chad Young, Lindsay Carpp, Stephen De Rosa, Joseph J Campo, Augusto Nhabomba, Maxmillian Mpina, Chenjerai Jairoce, Greg Finak, Paige Haas, Carl Muriel, Phu Van, Héctor Sanz, Sheetij Dutta, Benjamin Mordmüller, Selidji T Agnandji, Núria Díez-Padrisa, Nana Aba Williams, John J Aponte, Clarissa Valim, Daniel E Neafsey, Claudia Daubenberger, M Juliana McElrath, Carlota Dobaño, Ken Stuart, Raphael Gottardo
Publikováno v:
eLife, Vol 11 (2022)
eLife
eLife, vol. 11, pp. e70393
eLife
eLife, vol. 11, pp. e70393
Background:In a phase 3 trial in African infants and children, the RTS,S/AS01 vaccine (GSK) showed moderate efficacy against clinical malaria. We sought to further understand RTS,S/AS01-induced immune responses associated with vaccine protection.Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f39dda5f2f260731aea5887d8a00c2
Autor:
Webster Daniel, Hill Adrian V.S.
Publikováno v:
Bulletin of the World Health Organization, Vol 81, Iss 12, Pp 902-909 (2003)
Malaria is a parasitic disease of major global health significance that causes an estimated 2.7 million deaths each year. In this review we describe the burden of malaria and discuss the complicated life cycle of Plasmodium falciparum, the parasite r
Externí odkaz:
https://doaj.org/article/c201ccb16d244dca9708989da9329cf8
Autor:
Michael A. Miles, Tegwen Marlais, Sayda El-Safi, Shyam Sundar, Tapan Bhattacharyya, Andrew K. I. Falconar, Guy Mollett, Bruno C Bremer Hinckel, Om Prakash Singh, Pascal Mertens
Publikováno v:
Clinical infectious diseases
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Visceral leishmaniasis (VL), caused by the Leishmania donovani complex, is a fatal, neglected tropical disease that is targeted for elimination in India, Nepal, and Bangladesh. Improved diagnostic tests are required for early case detectio
Autor:
Anabela Cordeiro da Silva, Nuno Santarém, Célia G. Amorim, Hugo Lima de Carvalho, Nuno Lima de Carvalho, Óscar Felgueiras, Margarida Brito, Susana Sousa
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Canine leishmaniasis is a major veterinary issue and also a public health challenge due to its zoonotic potential. In this context, serological evaluation is essential for Canine leishmaniasis management. Several serological alternatives, such as rap
Autor:
E. J. Remarque, Vinod Sommandas, Sumera Younis, Christophe Barnier-Quer, Patrice M. Dubois, Martin Friede, Clemens H. M. Kocken, Nicole vd.Werff, Nicolas Collin, Simon Heuking, Livia Brunner
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Immunology
BMC immunology, vol. 19, no. 1, pp. 6
BMC Immunology
BMC immunology, vol. 19, no. 1, pp. 6
Background: The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development. Here we describe a method which may enable vaccine
Autor:
David E. Lanar, Giampietro Corradin, Peter Burkhard, Christopher P. Karch, Tais A. P. F. Doll, Issa Nebie, Sara M. Paulillo
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-10 (2017)
Journal of Nanobiotechnology
Journal of Nanobiotechnology, vol. 15, no. 1, pp. 62
Journal of Nanobiotechnology
Journal of Nanobiotechnology, vol. 15, no. 1, pp. 62
Background The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists. One approach to the development of a malaria vaccine is to target the asexual blood stage that results in clinical symptoms.
Autor:
Steven W. Wingett, Kassim Kamaka, Danika L. Hill, Martin S. Zand, Jiong Wang, Elizabeth F. Wallin, Catherine Mkindi, François Spertini, Wim Pierson, Régine Audran, Daniel J. Bolland, Said Jongo, Sophie Houard, Michelle A. Linterman, Anne E. Corcoran, Edward J. Carr, Claudia Daubenberger
Publikováno v:
The Journal of experimental medicine, vol. 216, no. 8, pp. 1857-1873
The Journal of Experimental Medicine
The Journal of Experimental Medicine
A rational strategy to achieve optimal vaccine responses is to potentiate Tfh cells and the germinal center response. This work shows the adjuvant GLA-SE enhances circulating Tfh cells and enduring antibody responses to a malaria vaccine in Tanzanian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02643e911e2eb9a88542a1b440cd038
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
Autor:
Anna Salvioni, Sophie Blanié, Virginie Vasseur, Nicolas Blanchard, Roland S. Liblau, Marcy Belloy, Ellen A. Robey, Elsa Suberbielle, Emilie Bassot, Vincent Cantaloube-Ferrieu, Aurore Lebourg
Publikováno v:
Cell Reports
Cell Reports, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell Reports, Elsevier Inc, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell reports, vol 27, iss 11
Cell Rep
Cell Reports, Vol 27, Iss 11, Pp 3254-3268.e8 (2019)
Cell Reports, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell Reports, Elsevier Inc, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell reports, vol 27, iss 11
Cell Rep
Cell Reports, Vol 27, Iss 11, Pp 3254-3268.e8 (2019)
Summary: Control of CNS pathogens by CD8 T cells is key to avoid fatal neuroinflammation. Yet, the modalities of MHC I presentation in the brain are poorly understood. Here, we analyze the antigen presentation mechanisms underlying CD8 T cell-mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b986ea5219ec9e06ea88a6de4a737a1c
https://hal.science/hal-02374306/document
https://hal.science/hal-02374306/document
Autor:
Gregory Nuel, Paulin Sonon, Adrian J. F. Luty, Gilles Cottrell, Ibrahim Sadissou, André Garcia, Roukiyath Amoussa, Tania d’Almeida, Ambaliou Sanni, Shirley Longacre, D. Courtin, Aziz Bouraima, Florence Migot-Nabias, Rafiou Adamou, Célia Dechavanne, Michael Theisen, Kabirou Moutairou, Edmond J. Remarque, Achille Massougbodji, Jacqueline Milet, Agnès Le Port
Publikováno v:
Malaria Journal
Malaria Journal, 2019, 18, pp.194. ⟨10.1186/s12936-019-2831-x⟩
Adamou, R, Dechavanne, C, Sadissou, I, d'Almeida, T, Bouraima, A, Sonon, P, Amoussa, R, Cottrell, G, Le Port, A, Theisen, M, Remarque, E J, Longacre, S, Moutairou, K, Massougbodji, A, Luty, A J F, Nuel, G, Migot-Nabias, F, Sanni, A, Garcia, A, Milet, J & Courtin, D 2019, ' Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort ', Malaria Journal, vol. 18, 194 . https://doi.org/10.1186/s12936-019-2831-x
Malaria Journal, BioMed Central, 2019, 18, pp.194. ⟨10.1186/s12936-019-2831-x⟩
Malaria Journal, Vol 18, Iss 1, Pp 1-11 (2019)
Malaria Journal, 2019, 18, pp.194. ⟨10.1186/s12936-019-2831-x⟩
Adamou, R, Dechavanne, C, Sadissou, I, d'Almeida, T, Bouraima, A, Sonon, P, Amoussa, R, Cottrell, G, Le Port, A, Theisen, M, Remarque, E J, Longacre, S, Moutairou, K, Massougbodji, A, Luty, A J F, Nuel, G, Migot-Nabias, F, Sanni, A, Garcia, A, Milet, J & Courtin, D 2019, ' Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort ', Malaria Journal, vol. 18, 194 . https://doi.org/10.1186/s12936-019-2831-x
Malaria Journal, BioMed Central, 2019, 18, pp.194. ⟨10.1186/s12936-019-2831-x⟩
Malaria Journal, Vol 18, Iss 1, Pp 1-11 (2019)
BACKGROUND: Substantial evidence indicates that cytophilic IgG responses to Plasmodium falciparum merozoite antigens play a role in protection from malaria. The specific targets mediating immunity remain unclear. Evaluating antibody responses in infa
Autor:
Tegwen Marlais, Tapan Bhattacharyya, Om Prakash Singh, Pascal Mertens, Quentin Gilleman, Caroline Thunissen, Bruno C. Bremer Hinckel, Callum Pearson, Bathsheba L. Gardner, Stephanie Airs, Marianne de la Roche, Kiera Hayes, Hannah Hafezi, Andrew K. Falconar, Osama Eisa, Alfarazdeg Saad, Basudha Khanal, Narayan Raj Bhattarai, Suman Rijal, Marleen Boelaert, Sayda El-Safi, Shyam Sundar, Michael A. Miles
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in cellular and infection microbiology
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Frontiers in cellular and infection microbiology
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Background: There is a recognized need for an improved diagnostic test to assess post-chemotherapeutic treatment outcome in visceral leishmaniasis (VL) and to diagnose post kala-azar dermal leishmaniasis (PKDL). We previously demonstrated by ELISA an