Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Antigens, CD80/immunology"'
Publikováno v:
Transplant International, Vol. 21, No 11 (2008) pp. 1015-1028
Transplantation of cells, tissues and vascularized solid organs is a successful therapeutic intervention for many end-stage chronic diseases. The combination of co-stimulatory blockade with the delivery of negative signals to T cells through co-inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad2e3f2b409182beeaa656104df3d8b
https://doi.org/10.1111/j.1432-2277.2008.00726.x
https://doi.org/10.1111/j.1432-2277.2008.00726.x
Autor:
Jiong Tian, Pablo Ramírez, Gang Mai, Maria-Luisa del Rio, Jose-Ignacio Rodriguez-Barbosa, Leo Buhler
Publikováno v:
Xenotransplantation, Vol. 14, No 3 (2007) pp. 243-8
We have previously demonstrated that costimulatory blockade with anti-CD40L monoclonal antibody (mAb) prolongs the survival of non-vascularized concordant rat to mouse islet xenografts. Here, we examine whether signaling through the PD-1/PD-1L pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db1ca4bb6f137ada5ee17e636867b51
https://archive-ouverte.unige.ch/unige:35014
https://archive-ouverte.unige.ch/unige:35014
Autor:
Mario P. Colombo, Iñigo Tirapu, Mikel Zaratiegui, Jesús Prieto, Carmen Berasain, Ignacio Melero, Pedro Berraondo, Puri Fortes, Oihana Murillo, Alvaro Gonzalez, Ainhoa Arina, Eduardo Huarte, Lieping Chen, Cristiana Guiducci
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Artificially enforced expression of CD80 (B7-1) and CD86 (B7-2) on tumor cells renders them more immunogenic by triggering the CD28 receptor on T cells. The enigma is that such B7s interact with much higher affinity with CTLA-4 (CD152), an inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612a10add79d6ee2858a53fa6926a004
https://hdl.handle.net/10171/21800
https://hdl.handle.net/10171/21800