BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination

Autor: Daniel E. Speiser, Pedro Romero, Laurent Derré, Camilla Jandus, Olivier Michielin, Daniel Olive, Sonia Pastor, Jean-Paul Rivals, Donata Rimoldi

Publikováno v: Journal of Clinical Investigation, vol. 120, no. 1, pp. 157-167
Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070

The function of antigen-specific CD8+ T cells, which may protect against both infectious and malignant diseases, can be impaired by ligation of their inhibitory receptors, which include CTL-associated protein 4 (CTLA-4) and programmed cell death 1 (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21284e9eff3c34c2f726a6abd031552
https://doi.org/10.1172/jci40070

Human Leukocyte Transmigration Across Galα(1,3)Gal-Negative Porcine Endothelium Is Regulated by Human CD18 and CD99

Autor: Mårten K J Schneider, Maddalena Ghielmetti, Daniel M. Rhyner, Maria Antsiferova, Jorg Dieter Seebach

Publikováno v: Transplantation, Vol. 87, No 4 (2009) pp. 491-499

BACKGROUND: In pig-to-human xenotransplantation cross-species receptor interactions mediate cellular infiltration and rejection of porcine grafts. However, the mechanisms responsible for recruitment of human leukocyte subsets across porcine endotheli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a77046a68b623cd2da059788a5dfbf
https://doi.org/10.1097/tp.0b013e318195fb8d

Both TNF receptors are required for direct TNF‐mediated cytotoxicity in microvascular endothelial cells

Autor: Rudolf Lucas, Gabriel Núñez, Georges E. Grau, Michael S. Pepper, Wim A. Buurman, Christine Giroud, Yves Donati, Lucie Fransen, Peter M. Suter, Marusa Hribar, Irene Garcia, Stefano J. Mandriota

Publikováno v: European Journal of Immunology, 28(11), 3577-3586. Wiley
European Journal of Immunology, Vol. 28, No 11 (1998) pp. 3577-3586

Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, University Medical Center, University of Geneva, Switzerland. lucas@cmu.unige.chThe conditions under which tumor necrosis factor-alpha (TNF) induces apoptosis in primary microva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913c38545717d7d2aef15e9610d62eb0
https://doi.org/10.1002/(sici)1521-4141(199811)28:11<3577::aid-immu3577>3.0.co

Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1

Autor: Sussan Nourshargh, Beat A. Imhof, Britta Engelhardt, Abigail Woodfin, Elisabetta Dejana, Mathieu-Benoit Voisin

Publikováno v: Blood, Vol. 113, No 24 (2009) pp. 6246-57

Leukocyte transmigration is mediated by endothelial cell (EC) junctional molecules, but the associated mechanisms remain unclear. Here we investigate how intercellular adhesion molecule-2 (ICAM-2), junctional adhesion molecule-A (JAM-A), and platelet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f12ee3b073bda02c33dbde69e07526
https://pubmed.ncbi.nlm.nih.gov/19520815