Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Antigens, Bacterial/genetics/immunology"'
Autor:
Arjan W. Griffioen, Elisabeth J. M. Huijbers, Judy R. van Beijnum, Patrycja Nowak-Sliwinska, Chung T. Lê, Kevin H. Mayo, Sofya Langman
Publikováno v:
Vaccine, Vol. 36, No 21 (2018) pp. 3054-3060
Huijbers, E J M, van Beijnum, J R, Lê, C T, Langman, S, Nowak-Sliwinska, P, Mayo, K H & Griffioen, A W 2018, ' An improved conjugate vaccine technology; induction of antibody responses to the tumor vasculature ', Vaccine, vol. 36, no. 21, pp. 3054-3060 . https://doi.org/10.1016/j.vaccine.2018.03.064
Vaccine, 36(21), 3054-3060. Elsevier BV
Huijbers, E J M, van Beijnum, J R, Lê, C T, Langman, S, Nowak-Sliwinska, P, Mayo, K H & Griffioen, A W 2018, ' An improved conjugate vaccine technology; induction of antibody responses to the tumor vasculature ', Vaccine, vol. 36, no. 21, pp. 3054-3060 . https://doi.org/10.1016/j.vaccine.2018.03.064
Vaccine, 36(21), 3054-3060. Elsevier BV
The induction of an antibody response against self-antigens requires a conjugate vaccine technology, where the self-antigen is conjugated to a foreign protein sequence, and the co-application of a potent adjuvant. The choice of this foreign sequence
Autor:
Anne-Françoise Rochat, Claire-Anne Siegrist, Karen Lingnau, Else Marie Agger, Arun T. Kamath, Paul-Henri Lambert, Mario Paolo Valenti, Alexander von Gabain, Peter Andersen
Publikováno v:
European Journal of Immunology, Vol. 38, No 5 (2008) pp. 1247-56
Vaccine efficacy largely depends upon DC targeting and activation. The most potent TLR soluble ligands induce diffuse DC activation, which may be associated with marked pro-inflammatory responses and possibly adverse effects. This raises the concern