Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Antigen Processing & Recognition"'
Publikováno v:
F1000Research, Vol 6 (2017)
The cell’s ability to communicate with the extracellular environment, with other cells, and with itself is a crucial feature of eukaryotic organisms. In the immune system, T lymphocytes assemble a specialized structure upon contact with antigen-pre
Externí odkaz:
https://doaj.org/article/8c7e48ea96bb4bd7af46227d6962d0e3
Autor:
D. Branch Moody, Sara Suliman
Publikováno v:
F1000Research, Vol 6 (2017)
The human cluster of differentiation (CD)1 system for antigen display is comprised of four types of antigen-presenting molecules, each with a distinct functional niche: CD1a, CD1b, CD1c, and CD1d. Whereas CD1 proteins were thought solely to influence
Externí odkaz:
https://doaj.org/article/528ecb1d0dbc44a896d5607702818e94
Autor:
Antony J. Cutler, Joao Oliveira, Ricardo C. Ferreira, Ben Challis, Neil M. Walker, Sarah Caddy, Jia Lu, Helen E. Stevens, Deborah J. Smyth, Marcin L. Pekalski, Jane Kennet, Kara M.D. Hunter, Ian Goodfellow, Linda S. Wicker, John A. Todd, Frank Waldron-Lynch
Publikováno v:
Wellcome Open Research, Vol 2 (2017)
Background: The infection of a participant with norovirus during the adaptive study of interleukin-2 dose on regulatory T cells in type 1 diabetes (DILT1D) allowed a detailed insight into the cellular and cytokine immune responses to this prevalent g
Externí odkaz:
https://doaj.org/article/33207a608a7448449e1c7f84ab0c0e78
Autor:
Joe Grove, Ke Hu, Michelle J. Farquhar, Margaret Goodall, Lucas Walker, Mohammed Jamshad, Heidi E. Drummer, Roslyn M. Bill, Peter Balfe, Jane A. McKeating
Publikováno v:
Wellcome Open Research, Vol 2 (2017)
Background: Tetraspanins are small transmembrane proteins, found in all higher eukaryotes, that compartmentalize cellular membranes through interactions with partner proteins. CD81 is a prototypical tetraspanin and contributes to numerous physiologic
Externí odkaz:
https://doaj.org/article/f41961338a0f430a9ed88b5124c8416f
Autor:
David Voehringer
Publikováno v:
F1000Research, Vol 6 (2017)
Basophils are mainly known as pro-inflammatory effector cells associated with allergy and helminth infections. Although they were identified over 130 years ago, their in vivo functions are still poorly understood. New insights into basophil developme
Externí odkaz:
https://doaj.org/article/5903bd2ea3494486b9985d6c65e443d7
Publikováno v:
F1000Research, Vol 6 (2017)
The extracellular signal-regulated protein kinase (ERK) signalling pathway controls key cellular processes, such as cell cycle regulation, cell fate determination and the response to external stressors. Although ERK functions are well studied in a va
Externí odkaz:
https://doaj.org/article/a2ea0fa1549b49b3b7059552f93f09aa
Autor:
Antony J. Cutler, Joao Oliveira, Ricardo C. Ferreira, Ben Challis, Neil M. Walker, Sarah Caddy, Jia Lu, Helen E. Stevens, Deborah J. Smyth, Marcin L. Pekalski, Jane Kennet, Kara M.D. Hunter, Ian Goodfellow, Linda S. Wicker, John A. Todd, Frank Waldron-Lynch
Publikováno v:
Wellcome Open Research, Vol 2 (2017)
Background: The infection of a participant with norovirus during the adaptive study of interleukin-2 dose on regulatory T cells in type 1 diabetes (DILT1D) allowed a detailed insight into the cellular and cytokine immune responses to this prevalent g
Externí odkaz:
https://doaj.org/article/56ed1355e9ef4375b2cea85e1b46addf
Publikováno v:
F1000Research, Vol 6 (2017)
In contrast to conventional T lymphocytes, which carry an αβ T-cell receptor and recognize antigens as peptides presented by major histocompatibility complex class I or class II molecules, human γδ T cells recognize different metabolites such as
Externí odkaz:
https://doaj.org/article/5cce8a452f1b413d9335d041791a2e6f
Publikováno v:
F1000Research, Vol 6 (2017)
Lupus nephritis is a potentially reversible cause of severe acute kidney injury and is an important cause of end-stage renal failure in Asians and patients of African or Hispanic descent. It is characterized by aberrant exaggerated innate and adaptiv
Externí odkaz:
https://doaj.org/article/c5c2a2e8ab8c497f823716500e834eff
Publikováno v:
F1000Research, Vol 5 (2017)
Protein arrays are frequently used to profile antibody repertoires in humans and animals. High-throughput protein array characterisation of complex antibody repertoires necessitates the use of extensively validated secondary detection antibodies. Thi
Externí odkaz:
https://doaj.org/article/f88fefb8f4014d6dbfee72d2492dcfbc