Zobrazeno 1 - 10 of 68 pro vyhledávání: '"Antigen Encapsulation"'
1
IgG3 and IgM Identified as Key to SARS-CoV-2 Neutralization in Convalescent Plasma Pools
Autor: Christina Kober, Sandro Manni, Svenja Wolff, Thomas Barnes, Shatanik Mukherjee, Thomas Vogel, Lea Hoenig, Peter Vogel, Aaron Hahn, Michaela Gerlach, Martin Vey, Eleonora Widmer, Björn Keiner, Patrick Schuetz, Nathan Roth, Uwe Kalina
Publikováno v: PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0262162 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
Analysis of convalescent plasma derived from individuals has shown that IgG3 has the most important role in binding to SARS-CoV-2 antigens; however, this has not yet been confirmed in large studies, and the link between binding and neutralization has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05810268dfaadb1938980daeb2c94e43
http://europepmc.org/articles/PMC8726489
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2
Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms
Autor: Jaffer Alsolaiss, Nicholas R. Casewell, Edouard Crittenden, Nessrin Alomran, Stuart Ainsworth, Laura-Oana Albulescu, Robert A. Harrison
Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009659 (2021)
PLoS Neglected Tropical Diseases
Background Snakebite is a neglected tropical disease that causes high global rates of mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667c6e98cbb9374a7907833948e20cd6
https://doaj.org/article/7ac00559f88147a1afdb2e22c80d597c
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3
Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens
Autor: Zhifu Chen, Yue Yuan, Zhuo Zhao, Haiming Jing, Lang-Huan Lei, Xiaokai Zhang, Hao Zeng, Jinyong Zhang, Qingshan Xiong, Quanming Zou, Xiaoli Zhang, Qiang Gou, Jintao Zou
Publikováno v: PLoS Pathogens, Vol 17, Iss 7, p e1009752 (2021)
PLoS Pathogens
Highly immunogenic exotoxins are used as carrier proteins because they efficiently improve the immunogenicity of polysaccharides. However, their efficiency with protein antigens remains unclear. In the current study, the candidate antigen PA0833 from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1df5bb101aadbd58b20120f2de56ef8
https://doaj.org/article/ed48bfb67a2d44089ceaab1838503c02
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4
An inexpensive point-of-care immunochromatographic test for Talaromyces marneffei infection based on the yeast phase specific monoclonal antibody 4D1 and Galanthus nivalis agglutinin
Autor: Skorn Mongkolsuk, Akarin Intaramat, Sirida Youngchim, Anna Kaltsas, Kritsada Pruksaphon, Kavi Ratanabanangkoon, Pavinee Simsiriwong, Joshua D. Nosanchuk
Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009058 (2021)
PLoS Neglected Tropical Diseases
Talaromyces marneffei is a thermally dimorphic fungus that causes opportunistic systemic mycoses in patients with AIDS or other immunodeficiency syndromes. The purpose of this study was to develop an immunochromatographic strip test (ICT) based on a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c368a712874a0a7898f0438f2227a93
https://doaj.org/article/ca576bc5769643c88a9698bf890fa5b8
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5
Local autoimmune encephalomyelitis model in a rat brain with precise control over lesion placement
Autor: Lukasz Kalkowski, Dominika Golubczyk, Joanna Kwiatkowska, Malgorzata Domzalska, Piotr Walczak, Izabela Malysz-Cymborska
Publikováno v: PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262677 (2022)
Development of a novel, animal model for multiple sclerosis (MS) with reproducible and predictable lesion placement would enhance the discovery of effective treatments. Therefore, we would like to combine the advantages of the demyelination model wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ae14aef47a0c3313a0ae7a8bad8998
https://pubmed.ncbi.nlm.nih.gov/35061807
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7
Application of phage display technology for the production of antibodies against Streptococcus suis serotype 2
Autor: Pattarawadee Sulong, Suphachai Nuanualsuwan, Kannika Khantasup, Natsinee Anudit, Segura Mariela
Publikováno v: PLoS ONE, Vol 16, Iss 10, p e0258931 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
Streptococcus suis (S. suis) serotype 2 infection is a problem in the swine industry and responsible for most cases of human infection worldwide. Since current multiplex PCR cannot differentiate between serotypes 2 and 1/2, then serotype-specific ant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffa0ecc85296bcce78605e987c748e8
https://doaj.org/article/4fdd4cfd9b0c489dbccf7184a689f886
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8
In vitro evaluations on canine monocyte-derived dendritic cells of a nanoparticles delivery system for vaccine antigen against Echinococcus granulosus
Autor: Eyad Almouazen, Samira Azzouz-Maache, Nadège Milhau, Anne-Françoise Pétavy, T. Marchal, Imène Hellel-Bourtal, Sylvie E Bouteille, Uruguaysito Benavides
Publikováno v: PLoS ONE, Vol 15, Iss 2, p e0229121 (2020)
PLoS ONE
Since dogs play a central role in the contamination of humans and livestock with Echinococcus granulosus, the development of an effective vaccine for dogs is essential to control the disease caused by this parasite. For this purpose, a formulation ba
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9d18cca0f81f57763050f9653e84c2
https://doaj.org/article/11c81ec4c81d46e09fb61049612e3ad7
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9
Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses
Autor: Frederik, Walter, Elsa, Winter, Sascha, Rahn, Judith, Heidland, Saskia, Meier, Anna-Maria, Struzek, Marcus, Lettau, Lisa-Marie, Philipp, Silje, Beckinger, Lilli, Otto, Julia Luisa, Möller, Ole, Helm, Daniela, Wesch, Regina, Scherließ, Susanne, Sebens
Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0239369 (2020)
PLoS ONE
Cancer vaccinations sensitize the immune system to recognize tumor-specific antigens de novo or boosting preexisting immune responses. Dendritic cells (DCs) are regarded as the most potent antigen presenting cells (APCs) for induction of (cancer) ant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cbc32c90c31caa90885c75670682cd33
https://doaj.org/article/6e7ed2b478ca4a4f88e6a1f69cde7082
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10
Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes
Autor: Lori Garman, Hayati Demiraslan, Judith A. James, A. Darise Farris, Geert-Jan Boons, Rebecca J. Ingram, Uner Kayabas, Eric K. Dumas, Jimmy D. Ballard, Jason L. Larabee, Emily E. Muns, Rebecca M Sparks, Mehmet Doganay, Adriana Zamora
Publikováno v: PLoS One, 15(4), 1. Public Library of Science
PLoS ONE
Dumas, E K, Demiraslan, H, Ingram, R J, Sparks, R M, Muns, E, Zamora, A, Larabee, J, Garman, L, Ballard, J D, Boons, G-J, James, J A, Kayabas, U, Doganay, M & Farris, A D 2020, ' Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes ', PLoS ONE, vol. 15, no. 4, e0230782 . https://doi.org/10.1371/journal.pone.0230782
PLoS ONE, Vol 15, Iss 4, p e0230782 (2020)
Understanding immune responses to native antigens in response to natural infections can lead to improved approaches to vaccination. This study sought to characterize the humoral immune response to anthrax toxin components, capsule and spore antigens
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce36a6ffd7907e5cac03a3c9deecda17
https://dspace.library.uu.nl/handle/1874/421380
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