Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2 and CRASH-3) trials and UK trauma registry (Trauma and Audit Research Network) data

Autor: Tim Nutbeam, Ian Roberts, Lauren Weekes, Haleema Shakur-Still, Amy Brenner, Francois-Xavier Ageron

Publikováno v: British journal of anaesthesia, vol. 129, no. 2, pp. 191-199

BACKGROUND: Women are less likely than men to receive some emergency treatments. This study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients varies by sex and whether the receipt of TXA by trauma patients varies by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becdcf7aebd3f689d0a1405021dba28e
https://doi.org/10.1016/j.bja.2022.03.032

Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions

Autor: Robert J.J. van Es, Karin P M van Galen, Evelien P. Mauser-Bunschoten, Roger E. G. Schutgens, Eveline T. Engelen

Publikováno v: The Cochrane Library
Cochrane Database of Systematic Reviews, 12, CD011385. John Wiley and Sons Ltd
Cochrane Database of Systematic Reviews, 2019(4). John Wiley and Sons Ltd

Background Minor oral surgery or dental extractions (oral or dental procedures) are widely performed and can be complicated by hazardous oral bleeding, especially in people with an inherited bleeding disorder such as haemophilia or Von Willebrand dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee53049b1345cc79a087fc0b739c4e55
https://pubmed.ncbi.nlm.nih.gov/26704192

Predicting Venous Thromboembolic Events in Patients with Coronavirus Disease 2019 Requiring Hospitalization: an Observational Retrospective Study by the COVIDIC Initiative in a Swiss University Hospital

Autor: Eleftheria Kampouri, Paraskevas Filippidis, Benjamin Viala, Marie Méan, Olivier Pantet, Florian Desgranges, Jonathan Tschopp, Jean Regina, Eleftherios Karachalias, Christophe Bianchi, Maxime G. Zermatten, Katia Jaton, Salah Dine Qanadli, Pierre-Alexandre Bart, Jean-Luc Pagani, Benoit Guery, Lorenzo Alberio, Matthaios Papadimitriou-Olivgeris, null RegCOVID Research Group

Publikováno v: BioMed research international, vol. 2020, pp. 9126148
BioMed Research International, Vol 2020 (2020)
BioMed Research International

Background. Coronavirus disease 2019 (COVID-19) can result in profound changes in blood coagulation. The aim of the study was to determine the incidence and predictors of venous thromboembolic events (VTE) among patients with COVID-19 requiring hospi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d01a98560d919de12c6a94c1e6a5875
https://serval.unil.ch/notice/serval:BIB_458CAB0E5E15

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

Autor: Dániel Bereczki, Nikola Sprigg, Maia Beridze, Polly Scutt, Jegan Thanabalan, David J. Werring, Lelia Duley, David J. Seiffge, Alfonso Ciccone, Christine Roffe, Kailash Krishnan, Ian Roberts, Timothy J. England, Ann Charlotte Laska, Jason P. Appleton, Zhe Kang Law, Anna Członkowska, Hanne Christensen, Stuart J. Pocock, Rustam Al-Shahi Salman, Philip M.W. Bath, Ronan Collins, Juan José Egea-Guerrero, Thompson G. Robinson, Robert A. Dineen, Katie Flaherty, Şerefnur Öztürk, David K. Whynes

Publikováno v: Sprigg, N, Flaherty, K, Appleton, J P, Al-Shahi Salman, R, Bereczki, D, Beridze, M, Christensen, H, Ciccone, A, Collins, R, Czlonkowska, A, Dineen, R A, Duley, L, Egea-Guerrero, J J, England, T J, Krishnan, K, Laska, A C, Law, Z K, Ozturk, S, Pocock, S J, Roberts, I, Robinson, T G, Roffe, C, Seiffge, D, Scutt, P, Thanabalan, J, Werring, D, Whynes, D, Bath, P M & TICH-2 Investigators 2018, ' Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2) : an international randomised, placebo-controlled, phase 3 superiority trial ', Lancet Oncology, vol. 391, no. 10135, pp. 2107-2115 . https://doi.org/10.1016/S0140-6736(18)31033-X
Sprigg, N, Flaherty, K, Appleton, J P, Salman, R A S, Bereczki, D, Beridze, M, Christensen, H, Ciccone, A, Collins, R, Czlonkowska, A, Dineen, R A, Duley, L, Egea-Guerrero, J J, England, T J, Krishnan, K, Laska, A C, Law, Z K, Ozturk, S, Pocock, S J, Roberts, I, Robinson, T G, Roffe, C, Seiffge, D, Scutt, P, Thanabalan, J, Werring, D & Whynes, D & Bath, P M 2018, ' Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2) : an international randomised, placebo-controlled, phase 3 superiority trial ', The Lancet, vol. 391, no. 10135, pp. 2107-2115 . https://doi.org/10.1016/S0140-6736(18)31033-X

WOS: 000433257200026
PubMed: 29778325
Background Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in adul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abde10210c4f54bed5a84fb883b588dd
https://researchonline.lshtm.ac.uk/id/eprint/4647837/1/Tranexamic-acid-for-hyperacute-primary-IntraCerebral-Haemorrhage-TICH-2.pdf

The Effect of Tranexamic Acid and Gender on Intraoperative Bleeding in Orthognathic Surgery-A Randomized Controlled Trial

Autor: Else Marie Pinholt, Johannes Jakobsen Sidelmann, Jesper Jared Secher, Janne Ingerslev, Jens Jørgen Thorn

Publikováno v: Jared Secher, J, Sidelmann, J J, Ingerslev, J, Thorn, J J & Pinholt, E M 2018, ' The effect of Tranexamic acid and Gender on Intraoperative Bleeding in Orthognathic Surgery : A Randomized Controlled Trial ', Journal of Oral and Maxillofacial Surgery, vol. 76, no. 6, pp. 1327-1333 . https://doi.org/10.1016/j.joms.2017.11.015

Purpose: The purpose of this randomized trial was to measure the effect of intravenously administered tranexamic acid (TXA) on intraoperative blood loss (IOB) in patients undergoing bimaxillary orthognathic surgery (OS). Materials and Methods: The au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d313b78880f949dcf6fa203f7150ca6
https://pubmed.ncbi.nlm.nih.gov/29232560