Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Anticancer immunity"'
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1191 (2024)
Background: Compared with conventional chemotherapy and targeted therapy, immunotherapy has improved the treatment outlook for a variety of solid tumors, including lung cancer, colorectal cancer (CRC), and melanoma. However, it is effective only in c
Externí odkaz:
https://doaj.org/article/0402489f166c40bd83c7dca161293a2a
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite advances in cancer treatment, hepatocellular carcinoma (HCC), the most common form of liver cancer, remains a major public health problem worldwide. The immune microenvironment plays a critical role in regulating tumor progression and resista
Externí odkaz:
https://doaj.org/article/6ac78626cdcc44068032b4f5fa5cd2f9
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-28 (2023)
Abstract The diagnosis of brain metastasis (BrM) has historically been a dooming diagnosis that is nothing less than a death sentence, with few treatment options for palliation or prolonging life. Among the few treatment options available, brain radi
Externí odkaz:
https://doaj.org/article/0a9b32d84cda46b2ad98407dc5ba2e5a
Autor:
Tongyuan Qu, Wenshuai Zhang, Chenhui Yan, Danyang Ren, Yalei Wang, Yuhong Guo, Qianru Guo, Jinpeng Wang, Liren Liu, Lei Han, Lingmei Li, Qiujuan Huang, Lu Cao, Zhaoxiang Ye, Bin Zhang, Qiang Zhao, Wenfeng Cao
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Immunocheckpoint inhibitors (ICIs) have been widely used in the clinical treatment of lung cancer. Although clinical studies and trials have shown that patients can benefit significantly after PD-1/PD-L1 blocking therapy, less tha
Externí odkaz:
https://doaj.org/article/94717a917bd849f7bfab1dec7cfb6998
Autor:
Chengcheng Wang, Zheng He
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Despite advances in comprehending cancer biology, malignant gliomas remain incurable. The present work conducted a multi-omics analysis for investigating the significance of chloride intracellular channel 1 (CLIC1) in gliomas.Methods: M
Externí odkaz:
https://doaj.org/article/cee464851708413e9244ad66f27899fc
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundInflammatory cell death is a form of programmed cell death (PCD) that induces inflammatory mediators during the process. The production of inflammatory mediators during cell death is beneficial in standard cancer therapies as it can break t
Externí odkaz:
https://doaj.org/article/158079aed3334d56a0b6175fe9c93fd9
Autor:
Yangyang Ma, Yanli Xing, Hongmei Li, Ting Yuan, Bing Liang, Rongrong Li, Jianyu Li, Zhonghai Li, Shuying Li, Lizhi Niu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIrreversible electroporation (IRE) is a novel local tumor ablation approach with the potential to stimulate an antitumor immune response. However, it is not effective in preventing distant metastasis in isolation. This study aimed to compar
Externí odkaz:
https://doaj.org/article/bea1d740f3d14245b75998911585c6fb
Akademický článek
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Autor:
Hong Kyu Lee, Min-Woo Nam, Ryeo-Eun Go, Jihye Koo, Tae Hun Kim, Jun-Eui Park, Kyung-Chul Choi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114212- (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with high mortality and recurrence rate. In this study, we generated a human immune system mouse model by transplanting human peripheral blood mononuclear cells into NSG-B
Externí odkaz:
https://doaj.org/article/4bd55cf84e11420f81af692f73eef29b
Autor:
Zuodong Ye, Yiding Xiong, Wang Peng, Wenjie Wei, Lihong Huang, Juliana Yue, Chunyuan Zhang, Ge Lin, Feng Huang, Liang Zhang, Songguo Zheng, Jianbo Yue
Publikováno v:
Advanced Science, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract The aberrant regulation of PD‐L1 in tumor cells remains poorly understood. Here, the authors systematically investigate the endosomal trafficking of plasma membrane PD‐L1 in tumor cells. They show that plasma membrane PD‐L1 is continuo
Externí odkaz:
https://doaj.org/article/aaa98cb1d8e7493f91504c9aa69051c5