Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Anticancer compound"'
Autor:
Kanchan Birat, Reem Binsuwaidan, Tariq Omar Siddiqi, Showkat Rasool Mir, Nawaf Alshammari, Mohd Adnan, Rahila Nazir, Bushra Ejaz, Moien Qadir Malik, Rikeshwer Prasad Dewangan, Syed Amir Ashraf, Bibhu Prasad Panda
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1119 (2022)
Vincristine is an anti-cancer compound and one of the most crucial vinca alkaloids produced by the medicinal plant Catharanthus roseus (L.) G. Don. (Apocynaceae). This plant is home to hundreds of endophytic microbes, which produce a variety of bioac
Externí odkaz:
https://doaj.org/article/1f52f5f98f53446db001453fe05a9a5b
Akademický článek
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Autor:
David E. Mery, Amanda J. Compadre, Paola E. Ordóñez, Edward J. Selvik, Vladimir Morocho, Jorge Contreras, Omar Malagón, Darin E. Jones, Philip J. Breen, Michael J. Balick, Flavio G. Gaudio, Monica L. Guzman, Cesar M. Compadre
Publikováno v:
Molecules, Vol 27, Iss 9, p 2928 (2022)
A method to identify anticancer compounds in plants was proposed based on the hypothesis that these compounds are primarily present in plants to provide them with an ecological advantage over neighboring plants and other competitors. According to thi
Externí odkaz:
https://doaj.org/article/40f8a2a0e8cf443b9b3ef69fd55bc294
Autor:
Rabin Neupane, Saloni Malla, Mariam Sami Abou-Dahech, Swapnaa Balaji, Shikha Kumari, Digambar Kumar Waiker, N. S. Hari Narayana Moorthy, Piyush Trivedi, Charles R. Ashby, Chandrabose Karthikeyan, Amit K. Tiwari
Publikováno v:
Molecules, Vol 26, Iss 15, p 4417 (2021)
A novel series of 4-anilinoquinazoline analogues, DW (1–10), were evaluated for anticancer efficacy in human breast cancer (BT-20) and human colorectal cancer (CRC) cell lines (HCT116, HT29, and SW620). The compound, DW-8, had the highest anticance
Externí odkaz:
https://doaj.org/article/f9d33cedefe2484cbf2ef8031dc8093b
Autor:
José A. Carmona-Negrón, Mariola M. Flores-Rivera, Zaibeth Díaz-Reyes, Curtis E. Moore, Arnold L. Rheigold, Enrique Meléndez
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 6, Pp 868-871 (2016)
A new ferrocene complex, 16-ferrocenylmethyl-3β-hydroxyestra-1,3,5(10)-trien-17-one dimethyl sulfoxide monosolvate, [Fe(C5H5)(C24H27O2)]·C2H6OS, has been synthesized and structurally characterized by single-crystal X-ray diffraction techniques. The
Externí odkaz:
https://doaj.org/article/9d4db8c4ae474c07aca2cee9380ce146
Autor:
Hearn, Jessica M., Romero-Canelón, Isolda, Munro, Alison F., Fu, Ying, Pizarro, Ana M., Garnett, Mathew J., McDermott, Ultan, Carragher, Neil O., Sadler, Peter J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Jul . 112(29), E3800-E3805.
Externí odkaz:
https://www.jstor.org/stable/26466132
Publikováno v:
Marine Drugs, Vol 18, Iss 5, p 257 (2020)
Chlorophyll breakdown products are usually studied for their antioxidant and anti-inflammatory activities. The chlorophyll derivative Pheophorbide a (PPBa) is a photosensitizer that can induce significant anti-proliferative effects in several human c
Externí odkaz:
https://doaj.org/article/76b9cf518fc94e8e9a38951463128d9d
Autor:
Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Mutasem O. Taha, Salim S. Sabri, Jalal A. Zahra, Mohammad Azhar Aziz
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 1943-1957 (2015)
Background/Aims: The antileukemic potential of isoindigos make them desired candidates for understanding their mechanism of action. We have recently synthesized a novel group of pyridone-annelated isoindigos and identified the derivative 5'-Cl that i
Externí odkaz:
https://doaj.org/article/828e6706d5b9498d8c97266bc4b9de08
Autor:
Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Amre Nasr, Mohammad A. Aziz
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 1958-1974 (2015)
Background/Aims: In our quest to develop an isoindigo with improved efficacy and bioavailability, we recently synthesized a series of novel substituted pyridone-annelated isoindigo and evaluated their antiproliferative effects. We identified the comp
Externí odkaz:
https://doaj.org/article/b7ceffb93eb04401982e8506f8cc56be
Autor:
Claudio Luparello
Publikováno v:
Foundations. 1:3-20
It is known that in breast cancer biology, autophagy mainly plays a cytoprotective and anti-apoptotic role in vitro, being conceivably responsible for cell resistance to drug exposure and a higher metastatic attitude in vivo. Thus, the development of