Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Antibody receptor"'
Autor:
A. Petty, L. J. Glass, D. A. Rothmond, T. Purves-Tyson, A. Sweeney, Y. Kondo, S. Kubo, M. Matsumoto, C. Shannon Weickert
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background There is growing evidence that neuroinflammation may contribute to schizophrenia neuropathology. Elevated pro-inflammatory cytokines are evident in the midbrain from schizophrenia subjects, findings that are driven by a subgroup o
Externí odkaz:
https://doaj.org/article/f6aa88715eda4de59383c7e03a35f93a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Anti-drug antibody formation poses tremendous obstacles for optimal treatment of hemophilia A (HA). In this study, we sought to utilize chimeric receptor-modified natural regulatory T cells (Tregs) to target FVIII-specific memory B cells, which are r
Externí odkaz:
https://doaj.org/article/ba679ffdabd349ac97202bb5f125110c
Akademický článek
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Autor:
George W. Carnell, Martina Billmeier, Sneha Vishwanath, Maria Suau Sans, Hannah Wein, Charlotte L. George, Patrick Neckermann, Joanne Marie M. Del Rosario, Alexander T. Sampson, Sebastian Einhauser, Ernest T. Aguinam, Matteo Ferrari, Paul Tonks, Angalee Nadesalingam, Anja Schütz, Chloe Qingzhou Huang, David A. Wells, Minna Paloniemi, Ingo Jordan, Diego Cantoni, David Peterhoff, Benedikt Asbach, Volker Sandig, Nigel Temperton, Rebecca Kinsley, Ralf Wagner, Jonathan L. Heeney
Peer reviewed: True
The accelerated development of the first generation COVID-19 vaccines has saved millions of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The most successful vaccine candidates have used the
The accelerated development of the first generation COVID-19 vaccines has saved millions of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The most successful vaccine candidates have used the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf4852943e0706741ae2e8273b90f5
Autor:
Leo C. James, Leo Kiss
Publikováno v:
Seminars in Cell & Developmental Biology. 126:99-107
The cytosolic antibody receptor and RING E3 ligase TRIM21 targets intracellular, antibody-coated immune complexes for degradation and activates the immune system. Here we review how TRIM21 degrades diverse targets and how this activity can be exploit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff1ffb4d098c9e230d6a7fa4e1b1e50
https://doi.org/10.1016/j.semcdb.2021.11.005
https://doi.org/10.1016/j.semcdb.2021.11.005
Publikováno v:
Seminars in Cell & Developmental Biology. 126:138-149
Antibodies mediate the majority of their effects in the extracellular domain, or in intracellular compartments isolated from the cytosol. Under a growing list of circumstances, however, antibodies are found to gain access to the cytoplasm. Cytosolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5063e77d7de48209becb14d5307d81e3
https://doi.org/10.1016/j.semcdb.2021.09.012
https://doi.org/10.1016/j.semcdb.2021.09.012
Akademický článek
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Autor:
Cristiano Amarelli, Nina Pilat, Olivier Thaunat, Sophie Brouard, Christine S. Falk, Federica Casiraghi, Floriane Fusil, Nuria Montserrat, Katia Lefsihane, Katja Kotsch, Romy Steiner
Publikováno v:
Transplant International. 34:1594-1606
Cell therapy has emerged as an attractive therapeutic option in organ transplantation. During the last decade, the therapeutic potency of Treg immunotherapy has been shown in various preclinical animal models and safety was demonstrated in first clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f9a01c2871c860eedfc29e21c9ffee
https://doi.org/10.1111/tri.13972
https://doi.org/10.1111/tri.13972
Akademický článek
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Autor:
Hao Zheng, Dage Sun, Hai Yu, Hua Wang, Ning Kong, Wenzhen Qin, Yajuan Jiao, Xiaoyong Chen, Lingxue Yu, Tongling Shan, Guangzhi Tong, Sujie Dong, Wu Tong, Huanjie Zhai
Publikováno v:
Archives of Virology
Tripartite motif protein 21 (TRIM21) is an E3 ubiquitin ligase and cytosolic antibody receptor of the TRIM family. Previous reports have indicated that TRIM21 plays an important role during viral infection. This study aimed at examining the role of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9aac552e93466a1793d60ba4e0fc0e6
https://doi.org/10.1007/s00705-021-05080-4
https://doi.org/10.1007/s00705-021-05080-4